Navigation Links
Common Preterm Labor Drug Has More Side Effects Than Alternative,,Finds Study from Packard Children's Hospital and Stanford

Preterm labor is defined as labor before 37 weeks' gestation. Although it's not always possible to prevent premature birth, physicians strive to delay delivery for at least 48 hours. The extra time allows a doctor to arrange to transfer the woman to a medical facility experienced in treating premature infants and helps maximize the effectiveness of steroids used to help the fetus to prepare for the harsh outside world.

Magnesium sulfate, nifedipine and other preterm labor treatments, called tocolytics, are thought to work by relaxing overactive uterine muscles and halting ongoing cervical changes that may lead to delivery. But it's not been clear if one is better than the others. Force of habit has dictated the use of magnesium sulfate by many physicians in the absence of a compelling reason to choose an alternative.

Lyell and El-Sayed and their collaborators randomly assigned 192 patients at Packard Children's or Santa Clara Valley Medical Center who were in preterm labor to receive either magnesium sulfate, which is an intravenous treatment, or nifedipine, an oral treatment. They found that magnesium sulfate was more effective in achieving the study's primary outcome--preventing delivery for 48 hours with uterine quiescence. But there were no significant differences in the treatments' ability to delay delivery, in the gestational age of the newborn or in the birth weight of the infants. The researchers speculate that this seeming contradiction could be explained if nifedipine, rather than stopping a woman's contractions, simply renders them clinically ineffective.

However, two-thirds of the women who received magnesium sulfate experienced mild to severe side effects such as shortness of breath and fluid build-up in the lungs during the treatment. In contrast, one-third of the women who received nifedipine experienced side effects of the treatment, including headaches. Nifedipine is commonly used to treat high blood pressure and heart disease.<
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types
2. Encouraging Clinical Activity of GSKs Novel Cancer Immunotherapeutic Confirmed in Phase II Study in Patients with Most Common Form of Lung Cancer
3. Blood Levels of Paliperidone Extended-Release Tablets are Not Increased by Common Antidepressant
4. Researchers Discover a Common Variation in a Gene Segment that Increases the Risk for Prostate Cancer
5. Trichomoniasis: Most Common Curable STD in U.S. Affects 7.4 Million Annually
6. One-Third of Patients Discontinue Common Breast Cancer Therapy
7. New Study in Journal of Pediatrics Suggests Synagis (Palivizumab) May Reduce Subsequent Recurrent Wheezing in Preterm Infants
8. Preterm Infants with Respiratory Distress Syndrome: Incidence Rates of Death when Treated with Surfactant Replacement Therapies
9. Columbia Laboratories Reports Preliminary Findings from the Ongoing Data Analysis of the Phase III Clinical Study of PROCHIEVE 8% (progesterone gel) to Prevent Preterm Birth
10. New Quality Control Systems for Every Laboratory Application
11. Immunoassay Systems - Your Laboratory Workhorse
Post Your Comments:
(Date:7/10/2014)... 10, 2014  RESMED INC. (NYSE: RMD ) ... fiscal year ended June 30, 2014 results on Thursday, July ... A press release with ResMed,s results will be issued after ... a webcast to discuss operating results and future outlook. ... p.m. US Pacific Time and the live webcast of the ...
(Date:7/10/2014)... , July 10, 2014  Decision Resources ... surveyed infectious disease (ID) specialists are willing to ... Orbactiv (oritavancin) for use as OPAT, approximately two-thirds ... these agents to their hospital inpatients. However, our ... OPAT patients are initiated on OPAT following hospital ...
(Date:1/15/2014)... -- ChinaMarketResearchReports.com adds "China Orthopedic Instrument Industry Report, 2013-2015" ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) Benefiting from aging ... China,s orthopedic instrument industry has seen rapid ... from 3.28 billion yuan in 2006 to 9.85 billion ...
Breaking Medicine Technology:ResMed To Announce Fourth Quarter And Fiscal Year-End 2014 Results 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 3Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3
... DecisionView Inc., a leading provider of software ... sciences companies, today announced the release of StudyOptimizer ... solution for patient enrollment planning, tracking and forecasting. ... site performance and cost projections, StudyOptimizer 4.3 significantly ...
... Mich., July 19, 2011 Terumo Heart, Inc., a ... a patient implanted with the DuraHeart™ Left Ventricular Assist ... the mechanical circulatory support device.  Helga Gieseke, living in ... German Heart Institute Berlin) and is now one of ...
Cached Medicine Technology:DecisionView StudyOptimizer 4.3™ Enhances Market-Leading Enrollment Optimization Solution With Greater Visibility Into Site Performance and Cost Forecasting 2DecisionView StudyOptimizer 4.3™ Enhances Market-Leading Enrollment Optimization Solution With Greater Visibility Into Site Performance and Cost Forecasting 3German Patient Surpasses 5 Years of Support on DuraHeart™ Left Ventricular Assist Device 2German Patient Surpasses 5 Years of Support on DuraHeart™ Left Ventricular Assist Device 3
(Date:7/13/2014)... BC (PRWEB) July 13, 2014 Victorian ... excitement by promoting the rental of bikes for its ... historic downtown Victorian Hotel to tour the area using ... plus tax. Bicycle enthusiasts love to call Vancouver home, ... options for cycle travel and picturesque journeys through the ...
(Date:7/13/2014)... July 13, 2014 Fuel additives are ... gasoline, diesel, jet fuel, kerosene, and so on, in ... responsible for reducing the corrosion effects caused by fuels ... added to any fuel, provide economies of scale in ... escalate the overall cost of the fuel products. , ...
(Date:7/13/2014)... The Pearland, Texas location of The Little Gym, a ... to 12 years of age that offers everything from gymnastics, ... Summer Camps, is now under new ownership. , Kevin Berry ... spending over six years at The Little Gym of Bellaire ... Berry has over ten years of experience working with children, ...
(Date:7/13/2014)... July 13, 2014 Recently, MyDressCity.com, one ... women’s special occasion outfits, has released its new range ... the new products are available at discounted prices. Worldwide ... 2014. , In the company’s online shop, there ... of them are made with great materials. MyDressCity.com’s hot ...
(Date:7/13/2014)... Seattle, WA (PRWEB) July 13, 2014 According ... Vkool.com, this is a step by step guide on what ... impairment easily and quickly. Vkool writes in its review ... what foods to eat to revitalize their kidney health. Vkool ... book can help people reverse their damaged kidney functions naturally. ...
Breaking Medicine News(10 mins):Health News:Victorian Hotel Creates Excitement by Adding "Cycle the City" Bike Rentals for Its Vancouver Hotel Rooms 2Health News:North America Fuel Additives Market is Expected to Reach $8,100 Million by 2017 - New Report by MicroMarket Monitor 2Health News:North America Fuel Additives Market is Expected to Reach $8,100 Million by 2017 - New Report by MicroMarket Monitor 3Health News:North America Fuel Additives Market is Expected to Reach $8,100 Million by 2017 - New Report by MicroMarket Monitor 4Health News:The Little Gym of Pearland, TX Now Under New Ownership and Management 2Health News:Cheap Elegant Quinceanera Dresses Unveiled by MyDressCity.com 2Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 2Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 3
... HealthDay Reporter , MONDAY, Oct. 11 (HealthDay News) -- ... study involving human embryonic stem cells has been injected ... The patient, being cared for at the Shepherd Center ... injury. The center specializes in treating these types of ...
... outreach program staffed by current and former sex workers ... drug treatment among women in street-based sex work, according ... Excellence in HIV/AIDS (BC-CfE) and the University of British ... peer-reviewed medical journal Drug and Alcohol Dependence, ...
... cancer can lead some people to wonder if their risk ... than 85,000 postmenopausal women observed that regular physical activity, maintaining ... risk for women with, and without a family history of ... published online Oct. 12, 2010, by the journal Breast ...
... cancer who experience pain or depression also have a ... mouth and nausea, according to a report in the ... , one of the JAMA/Archives journals. Having many ... patients in primary care settings and those with chronic ...
... by the body becomes less effective in reducing blood ... risk of stroke in individuals without diabetes, according to ... of Neurology , one of the JAMA/Archives journals. ... sedentary lifestyle and obesity, according to background information in ...
... (AMD)including an intravitreous (into the eye) injection of a ... for use against the eye diseasedo not appear to ... or death when compared with existing therapies, according to ... of Ophthalmology , one of the JAMA/Archives journals. ...
Cached Medicine News:Health News:First Patient Treated in U.S.-Approved Embryonic Stem Cell Trial 2Health News:First Patient Treated in U.S.-Approved Embryonic Stem Cell Trial 3Health News:Peer-based outreach services for sex workers assist entry into detox and drug treatment 2Health News:Peer-based outreach services for sex workers assist entry into detox and drug treatment 3Health News:Breast-healthy lifestyle worthwhile, URMC study confirms 2Health News:Physical symptoms common, disabling among patients with cancer and pain or depression 2Health News:Insulin resistance may be associated with stroke risk 2Health News:Insulin resistance may be associated with stroke risk 3Health News:Certain new therapies for age-related eye disease do not appear to increase heart risks 2
The Tag-It™ Cystic Fibrosis ASR reagents can be used by high complexity CLIA approved laboratories for detection of up to 70 mutations and 6 variants (polymorphisms) in the cystic fibrosis tran...
Paraffin Block Storage System...
The Modular Storage Drawers provide permanent storage and identification of up to 165 embedding rings or 250 cassettes per drawer....
Improving on the technology that the world has come to expect from the original SHUR/Mark® Cassette and Slide Labelers, SHUR/Mark® PLUS offers many added enhancements....
Medicine Products: