Navigation Links
Common Preterm Labor Drug Has More Side Effects Than Alternative,,Finds Study from Packard Children's Hospital and Stanford

Preterm labor is defined as labor before 37 weeks' gestation. Although it's not always possible to prevent premature birth, physicians strive to delay delivery for at least 48 hours. The extra time allows a doctor to arrange to transfer the woman to a medical facility experienced in treating premature infants and helps maximize the effectiveness of steroids used to help the fetus to prepare for the harsh outside world.

Magnesium sulfate, nifedipine and other preterm labor treatments, called tocolytics, are thought to work by relaxing overactive uterine muscles and halting ongoing cervical changes that may lead to delivery. But it's not been clear if one is better than the others. Force of habit has dictated the use of magnesium sulfate by many physicians in the absence of a compelling reason to choose an alternative.

Lyell and El-Sayed and their collaborators randomly assigned 192 patients at Packard Children's or Santa Clara Valley Medical Center who were in preterm labor to receive either magnesium sulfate, which is an intravenous treatment, or nifedipine, an oral treatment. They found that magnesium sulfate was more effective in achieving the study's primary outcome--preventing delivery for 48 hours with uterine quiescence. But there were no significant differences in the treatments' ability to delay delivery, in the gestational age of the newborn or in the birth weight of the infants. The researchers speculate that this seeming contradiction could be explained if nifedipine, rather than stopping a woman's contractions, simply renders them clinically ineffective.

However, two-thirds of the women who received magnesium sulfate experienced mild to severe side effects such as shortness of breath and fluid build-up in the lungs during the treatment. In contrast, one-third of the women who received nifedipine experienced side effects of the treatment, including headaches. Nifedipine is commonly used to treat high blood pressure and heart disease.<
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Largest Cervical Cancer Vaccine Efficacy Trial Shows Cervarix Provides Excellent Protection Against Lesions Caused by Most Common Cancer-Causing Virus Types
2. Encouraging Clinical Activity of GSKs Novel Cancer Immunotherapeutic Confirmed in Phase II Study in Patients with Most Common Form of Lung Cancer
3. Blood Levels of Paliperidone Extended-Release Tablets are Not Increased by Common Antidepressant
4. Researchers Discover a Common Variation in a Gene Segment that Increases the Risk for Prostate Cancer
5. Trichomoniasis: Most Common Curable STD in U.S. Affects 7.4 Million Annually
6. One-Third of Patients Discontinue Common Breast Cancer Therapy
7. New Study in Journal of Pediatrics Suggests Synagis (Palivizumab) May Reduce Subsequent Recurrent Wheezing in Preterm Infants
8. Preterm Infants with Respiratory Distress Syndrome: Incidence Rates of Death when Treated with Surfactant Replacement Therapies
9. Columbia Laboratories Reports Preliminary Findings from the Ongoing Data Analysis of the Phase III Clinical Study of PROCHIEVE 8% (progesterone gel) to Prevent Preterm Birth
10. New Quality Control Systems for Every Laboratory Application
11. Immunoassay Systems - Your Laboratory Workhorse
Post Your Comments:
(Date:1/23/2015)... LONDON and BOSTON , January ... structure-guided drug discovery and development company, is delighted to announce ... has been awarded to Miles Congreve (Vice President ... co-founder) and Malcolm Weir (Chief Executive Officer and ...
(Date:1/22/2015)... UPI ), a medical device company that develops, ... dysfunctions, today reported financial results for the fiscal 2015 ... for the Company,s Urgent ®  PC Neuromodulation System grew ... as compared to $3.9 million in the third quarter ...
(Date:1/22/2015)... , Jan. 22, 2015  Bio-Techne Corporation (NASDAQ: ... the first member of the new Simple Plex platform ... This launch represents the re-branding of the previously acquired ... Plex platform is a transformative immunoassay technology which integrates ...
Breaking Medicine Technology:Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 2Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 4Uroplasty Reports Record Revenue in Fiscal Third Quarter 2Uroplasty Reports Record Revenue in Fiscal Third Quarter 3Uroplasty Reports Record Revenue in Fiscal Third Quarter 4Uroplasty Reports Record Revenue in Fiscal Third Quarter 5Uroplasty Reports Record Revenue in Fiscal Third Quarter 6Uroplasty Reports Record Revenue in Fiscal Third Quarter 7Uroplasty Reports Record Revenue in Fiscal Third Quarter 8Uroplasty Reports Record Revenue in Fiscal Third Quarter 9Uroplasty Reports Record Revenue in Fiscal Third Quarter 10Uroplasty Reports Record Revenue in Fiscal Third Quarter 11Uroplasty Reports Record Revenue in Fiscal Third Quarter 12Uroplasty Reports Record Revenue in Fiscal Third Quarter 13Uroplasty Reports Record Revenue in Fiscal Third Quarter 14Uroplasty Reports Record Revenue in Fiscal Third Quarter 15Uroplasty Reports Record Revenue in Fiscal Third Quarter 16Uroplasty Reports Record Revenue in Fiscal Third Quarter 17Uroplasty Reports Record Revenue in Fiscal Third Quarter 18Bio-Techne Launches Simple Plex Platform 2Bio-Techne Launches Simple Plex Platform 3
(Date:1/22/2015)... (PRWEB) January 23, 2015 Recently, Weddingshe.com has ... catalog, and has announced its highest annual revenues in the ... on its popular glamorous wedding dresses. , According to the ... important wedding dress promotions for them in 2015. This point ...
(Date:1/22/2015)... Payday lending practices in four southern ... financial distress to the states that permit them, according ... Center on Race and Wealth. , While they generate ... loans at the same time substantially depress economic activity, ...
(Date:1/22/2015)... a famous dress online store for wedding dresses and other ... of wedding dresses , and launches a site-wide women’s dress ... on your big day; the wedding gown is the most ... find the most suitable wedding dress. Now, we are proud ...
(Date:1/22/2015)... 2015 Step into a macabre world ... Museum of Virginia. Wicked Plants, the Museum’s latest featured ... 75 poisonous, carnivorous and diabolical plants inside of a ... uncover the biochemical, physical and neurological processes between botanicals ...
(Date:12/26/2014)... It is said that nothing makes a lady ... famous wedding dress supplier, shows its new selection of ... promotion. , UWDress.com’s navy cocktail gowns are the cornerstones ... high fashion styles. Simple dresses in bright neon colors can ...
Breaking Medicine News(10 mins):Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2Health News:Wicked Plants are taking over the Science Museum of Virginia 2Health News:UWDress.com Shows Its New Navy Cocktail Dresses For 2015 2
... Scripps ... from the American Nurses Credentialing Center (ANCC). , ... La Jolla, CA (Vocus) June 16, 2010 -- ... excellence from the American Nurses Credentialing Center (ANCC). , , , , ,The new ...
... a majority of cases, due to late diagnosis of the ... Biodesign Institute at Arizona State University, along with Arturo Ramirez ... Center in Seattle, used a novel method for identifying ... appear. The work, which appeared recently in the ...
... ... for everyone: Protect your PC and files at home with free ... of portable storage devices (USB Flash Drives, external hard drives, digital ... and MACs,• Free data loss and theft protection for home and individual ...
... (ASTRO) continued to advance its Target Safely initiative by ... meeting on Device Improvements to Reduce the Number of ... June 9 and 10. ASTRO commends the FDA on ... develop data, which will help inform the FDA,s actions ...
... drug abuse, study finds , WEDNESDAY, June 16 (HealthDay News) ... abuse treatment have nearly doubled between 1992 and 2008, a ... and/or marijuana abuse among men and women aged 50 and ... 12 percent by 2008, according to researchers from the U.S. ...
... in French . , Montreal, June 16, ... Research in Immunology and Cancer (IRIC) of the Universit de ... three cancer-causing genes in acute lymphoblastic leukemia. Published in the ... on the complex interaction between the genes and their contributions ...
Cached Medicine News:Health News:Scripps Memorial Hospital La Jolla First in San Diego to Achieve Magnet Nursing Re-designation 2Health News:Scripps Memorial Hospital La Jolla First in San Diego to Achieve Magnet Nursing Re-designation 3Health News:Blood relations 2Health News:Blood relations 3Health News:My Endpoint Protector Device Control is Now Available for Home Users Free of Charge 2Health News:My Endpoint Protector Device Control is Now Available for Home Users Free of Charge 3Health News:My Endpoint Protector Device Control is Now Available for Home Users Free of Charge 4Health News:'Graying' of Drug Users at U.S. Treatment Centers 2Health News:Montreal researchers shed light on common juvenile cancer 2
... been selling replacement bulbs on ... we are extremely proud of ... out our catalog of replacement ... light bulbs specials. ,Check ...
... Direct has been selling replacement ... 1996, and we are extremely ... guarantee. Check out our catalog ... our discount light bulbs specials. ...
... has been selling replacement bulbs ... and we are extremely proud ... Check out our catalog of ... discount light bulbs specials. ...
... Bulb Direct has been selling ... since 1996, and we are ... satisfaction guarantee. Check out our ... see our discount light bulbs ...
Medicine Products: