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Clinical Trial Data (Phase 2a) Regarding Inhaled Amikacin Will Be,Presented at American Thoracic Society International Conference

in formulated for inhalation for the adjunctive treatment of gram-negative pneumonia in ventilated patients diagnosed with hospital or ventilator associated pneumonia. This new inhaled antibiotics product candidate leverages Nektar's proprietary Aerosol Generator that is designed to rapidly deliver aerosolized antibiotics to the deep lungs, both within and outside of a ventilator system. The result is a potentially faster-acting, potentially more effective treatment modality which provides key advantages over traditional pneumatic or ultra-sonic nebulizer.

ABOUT HOSPITAL-ACQUIRED GRAM-NEGATIVE PNEUMONIA:

Hospital-acquired, gram-negative bacterial pneumonia is a serious problem which afflicts patients even in the world's most advanced clinical settings. It is most commonly acquired by patients in intensive care units who have been put on ventilators for breathing assistance. Current treatment involves the administration of intensive antibiotics, supplemental oxygen, and intravenous fluids. Some 25-50% of those who acquire gram-negative bacterial pneumonia will die from it.

ABOUT NEKTAR:

Nektar Therapeutics is a biopharmaceutical company with a mission to develop and enable differentiated therapeutics with its industry-leading pulmonary and PEGylation technology platforms. Nektar pulmonary and PEGylation technology, expertise, manufacturing capabilities and know-how have enabled nine approved products for partners, which include the world's leading pharmaceutical and biotechnology companies. Nektar also develops its own products by applying its pulmonary and PEGylation technology platforms to existing medicines with the objective to enhance performance, such as improving efficacy, safety and compliance.

This press release contains forward-looking statements regarding NKTR-061 and the company's pulmonary technology. These forward-looking statements involve risks and uncertainties, including but not limited to: (i) preclinical testing
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