Navigation Links
Clinical Data Reported on Vidaza in Hematologic Malignancies and,Advanced Solid Tumors

ay restore normal function to genes that are critical for differentiation and proliferation. The cytotoxic effects of azacitidine cause the death of rapidly dividing cells, including cancer cells that are no longer responsive to normal growth control mechanisms. Non-proliferating cells are relatively insensitive to Vidaza.

Important Safety Information

Vidaza is contraindicated in patients with a known hypersensitivity to azacitidine or mannitol and in patients with advanced malignant hepatic tumors. In clinical studies, the most commonly occurring adverse reactions were nausea (70.5%), anemia (69.5%), thrombocytopenia (65.5%), vomiting (54.1%), pyrexia (51.8%), leukopenia (48.2%), diarrhea (36.4%), fatigue (35.9%), injection site erythema (35.0%), constipation (33.6%), neutropenia (32.3%) and ecchymosis (30.5%). Other adverse reactions included dizziness (18.6%), chest pain (16.4%), febrile neutropenia(16.4%), myalgia (15.9%), injection site reaction (13.6%), aggravated fatigue (12.7%) and malaise (10.9%). Because treatment with Vidaza is associated with neutropenia and thrombocytopenia, complete blood counts should be performed as needed to monitor response and toxicity, but at a minimum, prior to each dosing cycle. Because azacitidine is potentially hepatotoxic in patients with severe pre-existing hepatic impairment, caution is needed in patients with liver disease. In addition, azacitidine and its metabolites are substantially excreted by the kidneys and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, it may be useful to monitor renal function. Vidaza may cause fetal harm. While receiving treatment with Vidaza, women of childbearing potential should avoid becoming pregnant, and men should avoid fathering a child. In addition, women treated with Vidaza should not nurse.

About MDS

The highest prevalence of MDS is i
'"/>




Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29

Related medicine technology :

1. Genetic Analysis Systems Enter the Clinical Mainstream
2. Clinical Study Shows Regenecare Relieves Pain and Itching of Skin Rashes Caused by Widely Used Cancer Drugs
3. Large Geographic Differences in EpiPen Prescriptions in the U.S., From the Journal of Allergy and Clinical Immunology
4. Clinical Data Suggest Decreased Bleeding Risk in People With Severe Hemophilia A While Maintaining Factor VIII Levels Above One Percent
5. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
6. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
7. Corgenix Reports New Clinical Data Correlating AtherOx Technology With Vascular Disease
8. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
9. Protox Announces Positive Clinical Data from Prostate Cancer Study
10. AM-Pharma Announces Positive Results of Phase IIa Clinical Trial with Alkaline Phosphatase For Ulcerative Colitis
11. Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference
Post Your Comments:
(Date:3/27/2015)... , March 27, 2015 Levi & Korsinsky ... Inc. (NASDAQ: OHRP ) concerning possible violations of ... by the Company in connection with its study of ... http://zlk.9nl.com/ohr-pharmaceutical-ohrp or contact Joseph E. Levi, ... or by telephone at (212) 363-7500, toll-free: (877) 363-5972. ...
(Date:3/27/2015)... , March 27, 2015 /CNW Telbec/ - Russell ... Research-Based Pharmaceutical Companies (Rx&D), welcomes the 2015-2016 Quebec Budget, ... working group on the biopharmaceutical industry. However, the association ... "We commend the government,s intent to strive ... of measures to promote Quebec,s ...
(Date:3/27/2015)... Texas , March 27, 2015 The Temple ... in April to a 5,000-square-foot building at 1802 South First ... geographic area designated by the City of Temple ... Scott & White and the Central Texas Veterans Health Care ... and laboratory space to early stage biotechnology and life science ...
Breaking Medicine Technology:Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 2Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 3Temple Health & Bioscience District Relocates, Offers Office And Lab Space To Biotech Companies 2
... Bend Research Inc. ( www.bendres.com ), a leading independent ... has received a new U.S. patent covering a process ... pressure nozzles. The patent, which adds ... can be used to make solid amorphous dispersions with ...
... Inc. Magazine Tuesday ranked PercipEnz ... an exclusive ranking of the nation,s fastest-growing private ... at the most important segment of the economy—America,s ... 7-Eleven, Brooklyn Brewery, and Radio Flyer, maker of ...
Cached Medicine Technology:Bend Research Receives Patent for Preparing Spray-Dried Drug Dispersions Using Pressure Nozzles 2PercipEnz Makes Inc. Magazine's Fourth Annual List of America's Fastest-Growing Private Companies—the Inc. 5000 2PercipEnz Makes Inc. Magazine's Fourth Annual List of America's Fastest-Growing Private Companies—the Inc. 5000 3PercipEnz Makes Inc. Magazine's Fourth Annual List of America's Fastest-Growing Private Companies—the Inc. 5000 4
(Date:3/27/2015)... California (PRWEB) March 27, 2015 ... Entertainment’s EcoLuxe Lounge in the Stardust Penthouse on ... Debbie Durkin, Los Angeles’ leading sustainable product TV ... behind this unforgettable day-long event, which featured some ... and ecologically sound products and services. , “We ...
(Date:3/27/2015)... (PRWEB) March 27, 2015 The ... Germany” is an essential source of information on ... landscape in Germany. Germany’s increasingly elderly population and ... its pharmaceutical market. In 2013, the elderly accounted ... increase at Compound Annual Growth Rate (CAGR) of ...
(Date:3/27/2015)... Ticket Down is a reputable source of ... in Omaha, Nebraska on Friday, May 8th and Saturday, May ... will be added in Omaha as Garth has done in ... Garth Brooks World Tour is continuing its run throughout the ... Brooks and Trisha Yearwood will bring their act to Omaha, ...
(Date:3/27/2015)... UK (PRWEB) March 27, 2015 DrugDev ... Melissa (Liss) Easy was named to the 2015 Philadelphia ... Under 40 list spotlights 40 dynamic, up-and-coming leaders less ... and community involvement. Winners are honored at an awards ... of the Philadelphia Business Journal. , Lyn Kremer, Publisher ...
(Date:3/27/2015)... Francisco, CA (PRWEB) March 27, 2015 ... Recovery Yoga for functional fitness athletes. This new program ... a specific protocol for post-workout cool down. This program ... promote breath control and mental focus. , Karen ... “I started practicing yoga long before I started Crossfit® ...
Breaking Medicine News(10 mins):Health News:Choices Recovery Releases 'Salute to the Oscars' EcoLuxe Lounge Compilation Video 2Health News:Germany Healthcare, Regulatory and Reimbursement Landscape Market Research Report Available at RnRMarketResearch.com 2Health News:Germany Healthcare, Regulatory and Reimbursement Landscape Market Research Report Available at RnRMarketResearch.com 3Health News:Germany Healthcare, Regulatory and Reimbursement Landscape Market Research Report Available at RnRMarketResearch.com 4Health News:Cheap Garth Brooks Tickets for CenturyLink Center in Omaha: Ticket Down Slashes Garth Brooks Concert Tickets in Omaha, NE at the CenturyLink Center 2Health News:Cheap Garth Brooks Tickets for CenturyLink Center in Omaha: Ticket Down Slashes Garth Brooks Concert Tickets in Omaha, NE at the CenturyLink Center 3Health News:DrugDev Founder Melissa Easy is 2015 Philadelphia Business Journal 40 Under 40 Honoree 2Health News:Endure Yoga Introduces WOD Recovery Yoga 2
... , FRIDAY, April 15 (HealthDay News) -- Teens who ... for traffic crashes, a new study finds. But starting ... attention and reduce impulsiveness, another study finds. In 2008, ... Virginia Beach, Va., was about 41 percent higher than for ...
... HealthDay Reporter , THURSDAY, April 14 (HealthDay News) ... an artificial pancreas for the management of type 1 diabetes, ... sugar control and reduce the risk of dangerous low blood ... that the overall time that plasma glucose levels were in ...
... A comprehensive investigation of brain tissue donated to the ... tissue donation program, determined that one-third of the brain ... from the California State Department of Developmental Services revealed ... with both autism and epilepsy than for individuals with ...
... , THURSDAY, April 14 (HealthDay News) -- Kidney ... the new organ can develop accelerated narrowing of the ... lead to organ rejection. That,s the finding of ... biopsies from 99 kidney transplant patients -- 40 with ...
... calls are a common drain on the manpower and ... that identified Baltimore City,s top 911 callers and coupled ... cutting the number of such calls while helping callers ... conceived and implemented by the non-profit agency Baltimore HealthCare ...
... the risks and benefits of a medical intervention is not ... according to an article in the Hastings Center Report ... to disclose quantitative data to patients to help them make ... determine the best way to provide information to patients. ...
Cached Medicine News:Health News:Early School Start Tied to More Teen Crashes: Study 2Health News:Latest Artificial Pancreas Trials Reduce Risk of Low Blood Sugar 2Health News:Latest Artificial Pancreas Trials Reduce Risk of Low Blood Sugar 3Health News:Mortality rate is increased in persons with autism who also have epilepsy 2Health News:Targeting top 911 callers can trim cost, improve patient care 2Health News:Targeting top 911 callers can trim cost, improve patient care 3Health News:Too Much Information? Risk-benefit data does not always lead to informed decision-making 2Health News:Too Much Information? Risk-benefit data does not always lead to informed decision-making 3
... a stand-alone real-time monitoring, recording and ... defined set up, continuous monitoring and ... humidity. It offers non-restrictive sensor placements ... banks, laboratories, refrigerators, freezers, incubators and ...
... As many as three tests confirmed ... two tests according to FDA (Time Kill ... Care Antiseptic Drug Products) and one European ... Rub meets the relevant international efficacy specifications. ...
HIBICLENS' non-drying, low skin irritation potential promotes compliance with the frequent hand washing associated with today's clinical protocols....
... Care® Brand soaps, emulsions, washes and ... in healthy skin care, helping to ... healthy and soft even with heavy, ... contain petroleum-based substances that can cause ...
Medicine Products: