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Chi-Med Announces Positive Phase II Proof-of-Concept Data for,HMPL-004 in Ulcerative Colitis

n 0in 0pt; TEXT-ALIGN: justify">Chi-Med has a further botanical candidate, HMPL-002, a radio-sensitizer for head and neck and non-small cell lung cancer, which is in Phase I/II in the US and in proof-of-concept study in China. Chi-Med’s further pre-clinical drug development pipeline is focused on oncology and auto-immune indications. These compounds include synthetic and semi-synthetic single chemical entities in addition to botanical and natural product candidates.

At the meeting of Hutchison MediPharma’s Scientific Advisory Board held in Shanghai, China in late-June 2007, the Board, which includes key opinion leaders in the inflammatory bowel disease area, such as Dr. William J. Sandborn, Professor of Medicine at the Mayo Clinic College of Medicine, Vice Chair of the Division of Gastroenterology and Hepatology, and Director of the Inflammatory Bowel Disease Interest Group of the Mayo Clinic and Dr. Stephan Targan, Director of both the Inflammatory Bowel Disease Center and Division of Gastroenterology at Cedars-Sinai Medical Center, Los Angeles expressed high enthusiasm over HMPL-004.

Dr. Stephan Targan commented:

“HMPL-004 has a different mechanism of action. Based on the promising results from this study, HMPL-004 is warranted for further clinical studies to fully evaluate its efficacy and safety profile for the treatment of Ulcerative Colitis.”

Dr. Samantha Du, Chief Scientific Officer of Chi-Med and Managing Director of Hutchison MediPharma said:






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