Navigation Links
ChemoCentryx Presents Positive Phase 2 Clinical Data for,Traficet-EN in Crohn's Disease at the Digestive Disease Week 2007,Conference

Clear Anti-Inflammatory Activity Demonstrated Among Patients with Active Disease

MOUNTAIN VIEW, Calif., May 23, 2007 /PRNewswire/ -- ChemoCentryx, Inc., a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing orally-administered therapeutics that target the chemokine system, presented data today from the company's Phase 2 clinical trial of Traficet-EN (CCX282-B), an orally-active anti-inflammatory agent that targets the chemokine receptor CCR9. Clinical results demonstrate that Traficet-EN is well tolerated and shows clinical activity in the treatment of patients with active Crohn's disease. These data (Abstract #1031) were presented in an oral session, "Advances in Crohn's Disease," at the Digestive Disease Week (DDW) 2007 Conference in Washington, D.C. by Satish Keshav, M.D., Ph.D., Gastroenterologist at the John Radcliffe Hospital, Oxford, and a clinical investigator for the study.

"Traficet-EN demonstrated promising evidence of efficacy in the treatment of Crohn's disease patients, particularly among patients with elevated CDAI and CRP measurements at baseline. These results, achieved after only four weeks of treatment, justify broader study of Traficet-EN," said Dr. Keshav. "Traficet-EN's potential to control Crohn's disease with a safe and effective oral capsule represents a paradigm shift in the treatment of this condition and a truly meaningful improvement in patient care."

Patients enrolled in the Phase 2 clinical trial were randomized to receive a once-daily 250 mg capsule of Traficet-EN or placebo for 28 days. Both Crohn's Disease Activity Index (CDAI) scores and C-reactive protein (CRP) levels were measured at baseline and on study days 8, 15 and 29. Among a defined subgroup of 39 patients identified as having more active disease, with CDAI scores of greater than or equal to 250 and CRP of greater than 7.5 mg/L at baseline, Traficet-EN demonstr
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
2. European Society for Medical Oncology (ESMO) Presents Data from the Clinical Trial of MediGenes Cancer-Killing Virus in Press Conference
3. Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop
4. SemBioSys Presents Positive Insulin Data at the American Diabetes Association Conference
5. Tranzyme Pharma Presents Initial Phase IIa Data for its Novel Ghrelin Agonist, TZP-101, in Patients with Diabetic Gastroparesis
6. Novagali Pharma Presents at AACO the Results of its Pivotal Phase III Clinical Trial of Vekacia in Children Suffering From Vernal Keratoconjunctivitis
7. BioLife Solutions Presents Data on CryoStor at International Society for Cellular Therapy Annual Meeting
8. Genaera Presents Preclinical Data on Trodusquemine (MSI-1436) for the Treatment of Obesity at the American Diabetes Association 67th Scientific Session
9. Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Associations Annual Meeting
10. DiObex Presents Phase 2a Data of DIO-902 Demonstrating Trends of Improved Glycemic Control and Significant Reductions of LDL-Cholesterol and C-Reactive Protein
11. BioCryst Presents Phase I Peramivir Data at the Options for the Control of Influenza Conference
Post Your Comments:
(Date:6/19/2013)... CARLSBAD, Calif. , June 19, 2013 /PRNewswire/ ... ) today announces a licensing agreement granting Suzhou ... develop and manufacture siRNA therapeutics in ... technology.  Ribo will formulate proprietary siRNA molecules in ... platform designed to address human diseases with high ...
(Date:6/19/2013)... , June 19, 2013 Pharma ... new infographic summary of the results from an ... third of all respondents stated that CROs would be an ... of respondents will be running 6 or more clinical trials ... the Clinical Trial Supply USA Summit ...
(Date:6/18/2013)... 19, 2013 , Safinamide ... (PD) patients as add-on to levodopa ... motor symptoms in fluctuating PD patients as add-on ... Pharmaceuticals S.p.A. ("Newron"), a research and development company ... its partner Zambon S.p.A., a pharmaceutical company strongly ...
Breaking Medicine Technology:Life Technologies Signs Licensing Agreement with Suzhou Ribo Life Sciences for Development of siRNA Therapeutics in China 2Life Technologies Signs Licensing Agreement with Suzhou Ribo Life Sciences for Development of siRNA Therapeutics in China 3Life Technologies Signs Licensing Agreement with Suzhou Ribo Life Sciences for Development of siRNA Therapeutics in China 4Pharma IQ Presents the Latest Trends in Clinical Trial Supply 2Safinamide Phase III Study Results Presented at 2013 MDS Meeting 2Safinamide Phase III Study Results Presented at 2013 MDS Meeting 3Safinamide Phase III Study Results Presented at 2013 MDS Meeting 4Safinamide Phase III Study Results Presented at 2013 MDS Meeting 5Safinamide Phase III Study Results Presented at 2013 MDS Meeting 6
... YORK, Nov. 22, 2011 Reportlinker.com ... report is available in its catalogue: ... Companies M&A, Joint Ventures, R&D Pipeline, ... http://www.reportlinker.com/p0689250/Global-Diagnostic-Imaging-Companies-MA-Joint-Ventures-RD-Pipeline-and-Strategies.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_Imaging A unique ...
... Nov. 22, 2011 Reportlinker.com announces that a ... catalogue: Medical Robotics and Computer-Assisted ... http://www.reportlinker.com/p0687754/Medical-Robotics-and-Computer-Assisted-Surgery-The-Global-Market.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Surgical_Equipment REPORT SCOPE ... STUDY BACKGROUND Information technology plays ...
Cached Medicine Technology:Global Diagnostic Imaging Companies M&A, Joint Ventures, R&D Pipeline, and Strategies 2Global Diagnostic Imaging Companies M&A, Joint Ventures, R&D Pipeline, and Strategies 3Global Diagnostic Imaging Companies M&A, Joint Ventures, R&D Pipeline, and Strategies 4Global Diagnostic Imaging Companies M&A, Joint Ventures, R&D Pipeline, and Strategies 5Global Diagnostic Imaging Companies M&A, Joint Ventures, R&D Pipeline, and Strategies 6Medical Robotics and Computer-Assisted Surgery: The Global Market 2Medical Robotics and Computer-Assisted Surgery: The Global Market 3Medical Robotics and Computer-Assisted Surgery: The Global Market 4Medical Robotics and Computer-Assisted Surgery: The Global Market 5Medical Robotics and Computer-Assisted Surgery: The Global Market 6Medical Robotics and Computer-Assisted Surgery: The Global Market 7Medical Robotics and Computer-Assisted Surgery: The Global Market 8Medical Robotics and Computer-Assisted Surgery: The Global Market 9Medical Robotics and Computer-Assisted Surgery: The Global Market 10Medical Robotics and Computer-Assisted Surgery: The Global Market 11Medical Robotics and Computer-Assisted Surgery: The Global Market 12Medical Robotics and Computer-Assisted Surgery: The Global Market 13Medical Robotics and Computer-Assisted Surgery: The Global Market 14Medical Robotics and Computer-Assisted Surgery: The Global Market 15Medical Robotics and Computer-Assisted Surgery: The Global Market 16
(Date:6/20/2013)... Dr. Ramtin Kassir is one of ... and NYC and a top cosmetic surgeon in ... is to provide individualized care for a broad spectrum of ... surgeon is partnering with the new and emerging business consultancy ... its specialized needs. , "We are partnering with Tom and ...
(Date:6/20/2013)... June 20, 2013 Volume based manufacturing ... dramatically reduce the retail pricing of both it's WHEY ... replacement products. , Premier Natural Health’s whey protein ... food sources and are formulated to help maintain healthy ... intake and slow the aging process. , Ideal ...
(Date:6/20/2013)... Sydney, Australia (PRWEB) June 20, 2013 ... , research was presented recently, that can show similarities ... food. This could explain the current global obesity ... be addicted to food just as one can be ... Neuroscience and Applied Cognitive Science at the University of ...
(Date:6/19/2013)... (PRWEB) June 20, 2013 With the ... has put together their winter season Santiago day ... adventure day trips in and around Santiago this season, ... into Chile's Central Andes for backcountry skiing, challenging rock ... those who have always dreamed of skiing in ...
(Date:6/19/2013)... York, NY (PRWEB) June 19, 2013 The ... American bands in the country and folk music genre. This ... Brown (who is the lead vocals and guitarist), Jimmy De ... Hopkins (the bass guitarist and in vocals), Coy Bowles (guitarist ... de los Reyes (percussionist). The band was formed in ...
Breaking Medicine News(10 mins):Health News:Celebrity Plastic Surgeon Dr. Kassir Teams Up With X Factor Selling Systems to Enhance Patient Experience 2Health News:Premier Natural Health, a Leading Provider of Natural Food Products and Herbal Solutions, Reduces Prices On Its Popular Whey Protein Product 2Health News:Premier Natural Health, a Leading Provider of Natural Food Products and Herbal Solutions, Reduces Prices On Its Popular Whey Protein Product 3Health News:Research Suggests That Unhealthy Food Addiction Could Explain Global Obesity Epidemic 2Health News:Chile Montaña Announces Winter Season Santiago Day Trips 2Health News:Chile Montaña Announces Winter Season Santiago Day Trips 3Health News:Zac Brown Band Tickets for Raleigh, Columbia, Darien Center, Gilford, Minneapolis, Holmdel, Pittsburgh, Camden, Atlanta, Boston, Bethel, Toronto & Hartford Now Available 2
... year's Ellis Island Medal of Honor, established by the National ... ,Jacob Eapen, who will receive the award May 12, said ... a boost for all my future endeavours," Eapen told IANS ... of Honor are presented annually to US citizens of diverse ...
... publicized gay governor, James E. McGreevy appears to be knocking ... be in the news// for the right reasons. He has ... ,Former Gov. James E. McGreevy, who was brought up ... religion on Sunday at St. Bartholomew's Church in New York. ...
... maternity units in UK is an eye-opener to prevailing malfunctions ... In a sting operation conducted by BBC, some maternity units ... ,Some of the maternity units were facing an acute ... with work. The midwife in charge at a hospital where ...
... survival has improved over time. However, for recipients with ... in the issue of Liver Transplantation. ,HCV-induced ... transplantation in the U.S., however, previous studies have shown ... liver transplantation. The difference has become even more striking ...
... the United States the gays prefer to find out whether ... rather than use protection to prevent// catching the disease. The ... transmitting the virus, which is on the rise. ... with HIV virus and they continue to have unprotected sex. ...
... chicken are being fed contaminated feed is causing concern among the ... past few years//. The FDA is quick to play down the ... ,This concern came to light after some 38 chicken farms ... these farms fed the chicken for human consumption with the contaminated ...
Cached Medicine News:Health News:United Kingdom: Maternity Units Exposed! Leaves Much to Be Desired 2Health News:HCV Patients Survival After Liver Transplantation is Not Improving 2Health News:Unprotected Sex Among the Gays on the Rise 2Health News:Tainted Pet Food a Health Risk for Human? 2
Delicate side cutting wire cutter with carbide inserts....
Curved osteotome for bone removing....
... core product. It is created using the Panoramic200 ... for the screening of eye and non-eye diseases ... examination basis and is non-reimbursable. The optomap provides ... of the patients retina which is viewed on-screen ...
... The Pulse CDC Compact Cardiac Digital Camera is ... an open, patient-friendly gantry, and provides full sized ... camera into your clinic you need a flexible ... layout. Find out how the Pulse reduces ...
Medicine Products: