( evaluations were performed. Women were...)Cervarix, GSK Cervical Cancer Candidate Vaccine, Demonstrates 100,Percent Protection Against Precancerous Lesions Caused By,Cancer-Causing Human Papillomavirus Types 16 & 18 for More Than,Five Years,Health

About cervical cancer and its progression

Approximately 100 types of human papillomavirus have been identified to date and, of these, approximately 15 virus types are considered to cause cervical cancer. Virus types 16, 18, 45 and 31 are responsible for approximately 80 percent of cervical cancers globally. Persistent infection with a cancer-causing virus type leads to the formation of abnormal cells in the cervix, which, over time, may become precancerous or cancerous. Throughout their lifetime, women may be exposed to cancer-causing virus types and are potentially at risk of developing cervical cancer.

Globally, cervical cancer is the second leading cause of cancer death among women 20-39 years of age after breast cancer.

The GSK Cervical Cancer Candidate Vaccine Around the World

In addition to the Biologics License Application submitted for CERVARIX(R) with the U.S. Food and Drug Administration, GSK has submitted a marketing authorization application to the European Medicines Agency, Australia, Canada, and major countries in Asia and Latin America.

About GlaxoSmithKline

GlaxoSmithKline-one of the world's leading research-based pharmaceutical and healthcare companies-is committed to improving the quality of human life by enabling people to do more, feel better and live longer. For company information, please visit www.gsk.com/media.

GSK Biologicals (GSK Bio), one of the world's leading vaccine manufacturers, is headquartered in Rixensart, Belgium, where the majority of GlaxoSmithKline's activities in the field of vaccine research, development and production are conducted. GSK Bio employs more than 1,500 scientists, who are devoted to discovering new vaccines and developing more cost-effective and
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