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Cequent Pharmaceuticals Founder to Present tkRNAi Technology at the,American Association of Cancer Research Annual Meeting in Los,Angeles

CAMBRIDGE, Mass., April 13, 2007 /PRNewswire/ -- Cequent Pharmaceuticals, a pioneer in the development of novel products to deliver RNAi-based treatments to prevent and treat human disease, announced that its founder, Chiang Li, MD, will present a scientific poster on Cequent's proprietary TransKingdom RNA interference (tkRNAi(TM)) technology at the 2007 annual meeting of the American Association of Cancer Research (AACR). Co-inventor, Johannes Fruehauf, MD, PhD, of Beth Israel Deaconess Medical Center/Harvard Medical School, will also present at the centennial meeting, which will take place April 14 to 18, 2007, at the Los Angeles Convention Center.

The poster presentation, "Bacteria deliver RNA interference in vitro and in vivo for cancer therapy: tkRNAi," is scheduled for Tuesday, April 17, 2007, from 1 to 5 pm in the exhibit hall.

About tkRNAi(TM)- TransKingdom RNA Interference

RNA interference (RNAi) holds great promise for the development of novel therapies based on its high specificity and potency. One major difficulty impeding the wider development of RNAi-based therapies, however, is the need to deliver the molecules triggering RNAi (short interfering RNA) into the target cells and diseased tissues. Cequent's tkRNAi technology offers an elegant "Trojan horse" solution to the delivery problem; nonpathogenic bacteria are modified to produce and deposit mediators of RNA interference (short hairpin RNA) directly into the target cells. This method, which has been shown to induce gene silencing and therapeutic effects in multiple model systems, including live animals, forms the basis for Cequent's pipeline of clinical drug candidates.

About Cequent Pharmaceuticals, Inc.

An early-stage biopharmaceutical company, Cequent is pioneering the development of novel therapeutics to prevent and treat a wide range of human diseases - from inflammatory diseases to cancer - based on the
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