Navigation Links
CeNeRx BioPharma Announces Positive Phase I Results in First Human,Trial of Third Generation RIMA Antidepressant

iety, in contrast to the leading antidepressants available today that affect only the single neurotransmitter serotonin. This triple action mechanism has the potential for enhanced efficacy while the selective and reversible nature of RIMAs is intended to avoid toxic side effects.

"The excellent safety profile demonstrated in this study is the first confirmation in humans that Tyrima has the potential to deliver on the promise of the RIMA approach, and these positive results represent an important milestone for our company," said Barry Brand, chief executive officer of CeNeRx. "In contrast to other MAO inhibitors, our third generation RIMA series is designed to bind selectively and reversibly, with the goal of significantly reducing the cardiovascular risks and other side effects typically associated with the MAOI class. These safety results, along with the high plasma levels and favorable pharmacokinetics demonstrated in the study, support advancing Tyrima into a multiple dose safety study in late spring."

Tyrima could be the first RIMA antidepressant available in the U.S. market, and it has patent protection through 2026. CeNeRx has worldwide rights to develop and commercialize Tyrima.

The Tyrima Phase l safety trials began in January following a successful review of the Investigational New Drug (IND) application by the U.S. Food and Drug Administration.

About CeNeRx BioPharma

CeNeRx (SEN-er-ex) is a privately held clinical stage company developing and commercializing innovative and improved treatments for diseases of the central nervous system. The company focuses on identifying and developing promising therapeutics to treat diseases related to neurotransmitters, including anxiety, bipolar disorder, dementia, depression, epilepsy, neuropathic pain, schizophrenia, and Parkinson's and Alzheimer's diseases. CeNeRx's most advanced compounds, reversible inhibitors of monoamine oxidase, or RIMAs, are in Phase I and late pre-clinical d
'"/>




Page: 1 2 3

Related medicine technology :

1. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
2. Array BioPharma to Present at the C.E Unterbeg, Towbin Emerging Growth Conference
3. DOR BioPharma Announces Issuance of European Patent for Its Oral Multivalent Botulinum Toxin Vaccine BT-VACC
4. DOR BioPharma Announces Publication Describing Results of Its Multivalent Botulinum Toxin Vaccine BT-VACC
5. Array BioPharma Reports New Clinical Data on Its Anti-Inflammatory Drugs
6. PDL BioPharma Announces Long-Term Nuvion Data Presented at 2007 Digestive Disease Week
7. AVI BioPharma Reports Positive Pre-Clinical Influenza Data
8. Helix BioPharma Corp. Announces Positive Phase II Clinical Results with its Topical Interferon Alpha-2b
9. Integrated BioPharmas Proprietary Vaccine Technology Achieves Strong Positive Results
10. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
11. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
Post Your Comments:
(Date:8/22/2014)...  - MediaLINC unlocks ... Lincor announced general availability of MediaLINC - ... range of education, entertainment and clinical content direct to ... , " Lincor has already ... engagement to bedside smart devices, " comments Dan ...
(Date:8/21/2014)... Aug. 21, 2014  Aptuit LLC announces that ... Indiana , has enhanced its capabilities in ... small and large molecules, including biologic drugs, metabolites, ... maXisPlus Q-TOF mass spectrometer. In making ... Aptuit, said, "The expanded large molecule capability enhances ...
(Date:8/21/2014)... , Aug. 21, 2014 The spinal column is ... human body. Signals carried to and from the brain through ... and nervous system. Injury or ailment here can be life ... a loss of control over their body. Though back injury ... person,s life, there are more options available to make things ...
Breaking Medicine Technology:Lincor Unveils Next Generation TV-based Patient Engagement Solution 2Aptuit SSCI Adds Ultra High Resolution Q-TOF Mass Spectrometer for Large & Small Molecule Analyses 2Don't Live in Pain: Four Life Improving Benefits of Back Surgery 2
... Demonstrates Commitment to Patient Safety; Approved Sites Eligible to Advertise through ... , , ... July 28 The National Association of Boards of Pharmacy ... Kerr Drug as the first online pharmacy services to be approved ...
... , BOCA RATON, Fla. , July 28 ... with Tris Pharma, the company will market Methylphenidate Solution, ... Inc., under an Abbreviated New Drug Application (ANDA).  Under ... manufactured by Tris Pharma, and marketed and distributed by ...
Cached Medicine Technology:NABP Grants First 'Approved e-Advertiser' Status to Pharmahelper.com, QC Supply, and Kerr Drug 2NABP Grants First 'Approved e-Advertiser' Status to Pharmahelper.com, QC Supply, and Kerr Drug 3Breckenridge Pharmaceutical to Market Methylphenidate Oral Solution Through Agreement With Tris Pharma (Monmouth Junction, NJ) 2
(Date:8/22/2014)... (PRWEB) August 23, 2014 Recently, iFitDress.com, ... its new collection of discounted wedding gowns . ... announced that all these new products are provided with ... are very happy to unveil the new wedding gowns. ... special occasion gowns for ladies to choose from. What’s ...
(Date:8/22/2014)... The LSU Health New Orleans School of ... Traineeship grant to increase access to advanced nursing ... under-represented groups, as well as veterans. The Health ... of Health and Human Services awarded the two-year ... the grant,s project director., The Advanced Education Nursing ...
(Date:8/22/2014)... Natural Clear Vision , a how-to guide ... vision from legally blind to perfect 20/20 vision has caught ... , “There is a huge portion of the population today ... most people just think that’s the way it will always ... be pretty risky at times,” reports Michaels. “This program is ...
(Date:8/22/2014)... somatic mutation at amino acid 918 in the RET ... cell lung cancer (SCLC) tumors and enforced expression of ... signaling and cell growth. , SCLC is a highly ... lung cancers and is strongly associated with tobacco smoking. ... examined for genomic alterations and targeted therapies are approved ...
(Date:8/22/2014)... (PRWEB) August 22, 2014 Restore ... Sen and Dr. Samantha Pearson to help people discover ... avoid corrective vision surgery by instead improving their eyesight ... an investigative review. , “There’s a reason why ... in revenue each year—it’s because people just assume that ...
Breaking Medicine News(10 mins):Health News:Discounted Wedding Gowns For Sale At Leading Online Shop iFitDress.com 2Health News:Natural Clear Vision: Review Exposes Kevin Richardson’s Program for Restoring Vision Naturally 2Health News:Novel oncogenic RET mutation found in small cell lung cancer 2Health News:Restore My Vision Today: Review Exposes Natural Eye Restoration Guide by Dr. Sen and Dr. Samantha Pearson 2
... Delhi went on mass casual leave Monday, joining ... the sufferings of patients. ,The majority of ... University College of Medical Sciences (UCMS) and Safdarjung ... resentment against the government decision to implement 27 ...
... zero alcohol quotient is highly conducive for the cognitive ... research has suggested//. Infact, even moderated alcohol intake during ... unborn child. ,The study conducted by the University ... Washington, has shown that those children, whose mothers had ...
... over 3500 and an incalculable number of people injured after ... cope with the injured and the dead. ,The quake ... city of Yogyakarta which is near the southern coast of ... left the city in shambles, cutting off communications and road ...
... American study conducted by Arthur Krigsman, of New York ... links to autism//. MMR inoculation is given to young ... But recently there have been claims that the vaccine ... fall in the MMR vaccine uptake rate which has ...
... the world and it has drastically affected the sales of chicken ... for chicken// and the sales are slowly picking up in the ... stage. ,Mohamed Al Shafei, director of the General Union ... great deal in the past with a large number of chickens ...
... very similar to the technology in the United States, and ... for filling up nursing vacancies. With India also being rated ... are realizing their dream of seeking greener pastures. , ... from India who will be joining the hospital during this ...
Cached Medicine News:Health News:Mass Leave By Doctors Leaves Patients Helpless 2Health News:Indonesian Earthquake – Story of Destruction, Death and Disease 2
... replace the carpal scaphoid bone. The implant has ... under a shelf formed in the carpal trapezium ... the proximal hole for suture fixation. These temporarily ... period until a firm capsuloligamentous system has formed ...
... has the same anatomical configuration as the ... to provide for stability. The implant has ... use in suture fixation through the scaphoid ... while a capsuloligamentous system forms around the ...
... for four corner fusion of the capitate, ... hand. The plate is intended for use ... of function due to SLAC and SNAC ... rheumatoid arthritis. When combined with the specially ...
The 3.0 mm Cannulated Screw can be used with or without threaded washer. Uses 1.1 mm threaded or non-threaded guide wire. , ,The Threaded Washer provides a recessed internal buttress which allows the...
Medicine Products: