illed with a synthetic immunostimulatory DNA sequence called G10. CYT003-QbG10 is designed as a disease-modifying treatment and aims to induce a potent Th1 type immune response in order to suppress an "allergic" Th2 type immune response. An earlier, open-label phase IIa study with CYT003-QbG10 combined with an allergen extract of house dust mites at a standard dose showed excellent long-term efficacy in patients allergic to dust mites. Furthermore, two placebo-controlled phase IIa studies with CYT003-QbG10 delivered positive results in patients suffering from allergic rhinitis due to grass pollen allergy and house dust mite allergy. CYT003-QbG10 is currently being studied in clinical trials for the treatment of allergic rhinitis and atopic dermatitis.

Please feel free to contact us at the address below should you wish to receive further information, address questions, or arrange meetings with Cytos Biotechnology directly.

With best regards,

Claudine Blaser

For more information please contact:

Claudine Blaser, PhD Director Corporate Communications Cytos Biotechnology AG Wagistrasse 25, Postfach CH-8952 Schlieren (Zurich) Tel. +41 44 733 47 20 Fax. +41 44 733 47 18 e-mail: claudine.blaser@cytos.com www.cytos.com

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