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Biotec Pharmacon Announces Preliminary Results from the,Sloan-Kettering Clinical Study

TROMSØ, Norway, June 29, 2007-Preliminary results from the immunotherapeutic cancer study at Memorial Sloan-Kettering Cancer Center show a very good safety profile for SBG. Furthermore, encouraging responses on cancer development have been observed among several patients that have been treated with SBG in combination with the monoclonal antibody against neuroblastoma.

In line with the timetable described in the company's report for the 1st quarter 2007, all 24 patients have now been included in the clinical study at Memorial Sloan-Kettering Cancer Center (MSKCC). In this study, SBG is tested in combination with a monoclonal antibody (3F8) against the cancer form neuroblastoma. The patients are children that have developed metastatic neuroblastoma and are non-responders to previous conventional chemotherapy. These patients therefore maintain a very poor prognosis for survival, but earlier clinical studies at Sloan-Kettering have demonstrated positive effects in a similar patient population when treated with the cancer antibody 3F8. By using immune-stimulating adjuvants such as beta-glucans, the effects of the antibody treatment could be improved. The purpose of the present study was primarily to investigate if SBG leads to side effects in this particular combination treatment, but also to obtain the first indications whether SBG has a role together with monoclonal antibodies in the treatment of cancer patients.

Patients in the study have been treated at escalating dose levels of SBG from 10 and up to 120 milligram per kilo per day at the highest level. Of 24 patients that have been included in the trial, 23 patients are evaluable for safety, whereas 20 patients are evaluable for response. Sloan-Kettering has now reported preliminary data for these patients. It should be noted that the results are not considered definitive.

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