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Biosite Reports on Presentation of Preliminary Data From Sepsis,Program

ous biomarker measurements. Biosite intends to commercialize the panel of biomarkers under the product name Triage(R) Sepsis Panel.

In this study, blood samples were collected from approximately 1,000 patients presenting to the emergency department with signs and symptoms of sepsis. Samples were analyzed at Biosite using a prototype device. Following are preliminary study findings:

    *  The study data were based on samples from initial blood draws,

       suggesting that the test may be useful in the rapid assessment of

       patients.

    *  The sepsis biomarker panel may have clinical utility in risk assessment

       of patients presenting to the hospital and meeting diagnostic criteria

       for sepsis.

    *  The sepsis biomarker panel performed better as a risk assessment tool

       than markers in the literature, including procalcitonin and C-reactive

       protein.

A webcast of Dr. Rivers' presentation will be archived on the Biosite website at www.biosite.com until April 26, 2007. Dr. Rivers is a consultant to Biosite.

About the Triage Sepsis Panel

The Triage Sepsis Panel is a rapid point-of-care test intended to use simultaneous measurements of MIP-3, CRP and NGAL to aid in the assessment for risk of sepsis progression within 72 hours of patients presenting to the emergency department and meeting diagnostic criteria for sepsis. Biosite expects to commence a multi-center validation study called MINDSET (MultiMarker Index for the Risk Assessment of Sepsis in the Emergency Department) in the second quarter of 2007. The study is aimed at generating data to support a submission to the U.S. Food and Drug Administration (FDA). The Company also plans to seek CE marking for the product later this year.

Biosite is also evaluating other potential products in the category of sepsis, including biomarker targets that may be useful in the diagnosis of sep
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