Navigation Links
Bionovo to Present Recent Findings of BZL101, Its Anti-cancer,Agent, at the American Association of Cancer Research

EMERYVILLE, Calif., April 16, 2007 /PRNewswire-FirstCall/ -- Bionovo, Inc. will present findings on the mechanism of action of its anti-cancer agent BZL101, which is advancing to Phase 1/2 clinical testing for late stage breast cancer at the American Association of Cancer Research (AACR) being held at the Los Angeles Convention Center in Los Angeles, CA, April 14 - 17, 2007.

Bionovo's poster presentation will describe the pathway for cancer cell apoptosis (cell death) induced by BZL101 while leaving normal cells unaffected. As explained by Dr. Emma Shtivelman, Director of Cancer Research at Bionovo, the ability of BZL101 to induce apoptosis is due to attenuation of mitochondrial transmembrane potential (MTP) leading to the release of reactive oxygen species, causing inhibition of glycolysis and ending with induction of oxidative DNA damage.

A paper on BZL101's mechanism of action and unique selective properties based on the company's initial Phase 1 clinical trial was published late last year in the peer-reviewed journal, Breast Cancer Research and Treatment.

"BZL101's mechanism of action and unique selective properties" said Dr. Isaac Cohen, President and CEO of Bionovo, "are a result of some of the biological differences between cancer cells and normal cells. We are hoping that capitalizing on the difference will result in a safe and effective treatment for cancer."

Bionovo, Inc.

Bionovo is a drug development company focusing on the discovery of novel pharmaceutical agents for cancer and women's health. The company has two drugs in clinical testing. MF101 is in Phase 2 for quality of life conditions associated with menopause, and BZL101 is in Phase 1/2 for the treatment of advanced breast cancer. The company has an additional pipeline of drugs in development for breast cancer, pancreatic cancer and other menopausal symptoms with a total of 4 drug candidates expected to be in
'"/>




Page: 1 2 3

Related medicine technology :

1. Bionovos MF101 Shows Positive Safety, Tolerability and Efficacy in Phase 2 Trial
2. The Past, Present and Future of HLA Typing
3. Phase 3 Results for Dabigatran Etexilate, an Investigational Oral Anticoagulant, Presented Today at the XXIst Congress of the International Society on Thrombosis and Haemostasis
4. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
5. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
6. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
7. Generex Biotechnology to Make Presentations At 46th Annual Meeting of the European Society of Pediatric Endocrinology
8. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
9. ViaCell to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
10. Accelrys to Present to Investors at C.E. Unterberg Emerging Growth Opportunities Conference
11. Metabasis to Present at C.E. Unterberg, Towbin Emerging Growth Conference and Attend Pacific Growth Equities Conference
Post Your Comments:
(Date:9/2/2015)... About Duchenne muscular dystrophy Duchenne ... affects the male population. It is characterized by ... caused due to mutations in the dystrophin gene, ... dystrophin (a protein essential for maintaining healthy muscle ... muscle function, causes loss of ambulation, harms the ...
(Date:9/2/2015)... -- About Chronic Lymphocytic Leukemia Chronic ... production of lymphocytes. It has been observed that the ... to other parts of the body. This leukemia is ... buildup of the cancerous cells. During the course of ... and lymph nodes. The course of the disease is ...
(Date:9/2/2015)... DUBLIN , Sept. 2, 2015 Research and ... "Pharmaceutical Regulatory Affairs in China (Basel, Switzerland - November ... This seminar will provide a detailed overview of the key ... , Hong Kong , Macau ... cover: - All important aspects of gaining ...
Breaking Medicine Technology:Global Duchenne Muscular Dystrophy Drugs Market 2015-2019 2Global Duchenne Muscular Dystrophy Drugs Market 2015-2019 3Global Chronic Lymphocytic Leukemia Therapeutics Market 2015-2019 2Global Chronic Lymphocytic Leukemia Therapeutics Market 2015-2019 3Pharmaceutical Regulatory Affairs in China Seminar: Basel, Switzerland - November 26-27, 2015 2
... FRANCISCO, Oct. 14 Medizone International, Inc. ... round of AsepticSure(TM) trials have begun at Innovation Park, ... the first and second round of laboratory testing, this ... protocols necessary in order to obtain maximum bactericidal action ...
... Oct. 14 Cardiva Medical, Inc. announces today that its ... position of Chief Executive Officer at Innovative Energy, Inc., an ... of Cardiva Medical stated, "I would like to thank Glenn ... During his tenure as President, we have transformed Cardiva ...
Cached Medicine Technology:Medizone International Announces Third Round of AsepticSure 2Cardiva Medical, Inc. Announces the Departure of its President and his Appointment as CEO of Innovative Energy, Inc. 2Cardiva Medical, Inc. Announces the Departure of its President and his Appointment as CEO of Innovative Energy, Inc. 3
(Date:9/3/2015)... ... 2015 , ... Doctor Kayode Sotonwa can be counted on time ... on internal medicine keeps patients happy and healthy, something that is important to everyone. ... season, but even more so in the fall, when holiday eating and seasonal illnesses ...
(Date:9/3/2015)... ... 2015 , ... Fashion designer Kim (29 years old, Honolulu, HI) designed her ... the hit ABC series “Extreme Weight Loss” Season 5 . Standing just 5’1” ... herself with the motivation to transform when she designed a drop-dead-gorgeous dress and vowed ...
(Date:9/2/2015)... ... September 03, 2015 , ... Leah ... among the most influential leaders in healthcare, will offer the keynote address at ... place October 15-16, 2015, in Palm Harbor, Florida, at the Innisbrook Resort and ...
(Date:9/2/2015)... ... 2015 , ... Sara Bleich, Ph.D., associate professor of health ... an internationally recognized scholar on obesity prevention and control, has been selected for ... and 1996 graduate of Garrison Forest School, an all-girls’ independent school in Owings ...
(Date:9/2/2015)... , ... September 02, 2015 , ... The CRISPR-Cas9 ... using a complex of the Cas9 nuclease with either a chimeric single guide RNA ... The ability of any given guide RNA (sgRNA or crRNA) to create a break ...
Breaking Medicine News(10 mins):Health News:Doctor Kayode Sotonwa Highlights Expert Tips for Staying in Shape This Fall 2Health News:New “Extreme Weight Loss” Video Blog from the CU Anschutz Health and Wellness Center: Kim Begins with the End in Mind and Designs a Fashionable Future 2Health News:New “Extreme Weight Loss” Video Blog from the CU Anschutz Health and Wellness Center: Kim Begins with the End in Mind and Designs a Fashionable Future 3Health News:ACO Coalition Meeting to Feature Leapfrog’s Leah Binder 2Health News:ACO Coalition Meeting to Feature Leapfrog’s Leah Binder 3Health News:Dr. Sara Bleich, Garrison Forest Graduate, Selected for 2015-16 Class of White House Fellows 2Health News:GE Healthcare Webinar Discusses Improvements to CRISPR-Cas9 Gene Editing 2Health News:GE Healthcare Webinar Discusses Improvements to CRISPR-Cas9 Gene Editing 3Health News:GE Healthcare Webinar Discusses Improvements to CRISPR-Cas9 Gene Editing 4
... A commentary in the December issue of The Lancet ... on the transmission of a common pathogen the influenza ... to protect health care workers. Infectious diseases specialist Leonard Mermel, ... looks at the ongoing debate in light of the H1N1 ...
... the University of Southern California Center for Robotics ... evaluate robots as exercise coaches for adults of all ... The effort, entitled "Robot Motivator: Towards Adaptive Health Games ... virtual social characters on people,s motivation to exercise. ...
... Woman and Her Provider is the Best Choice for Screening ... mammography emphasizes that the best decision on screening is made ... woman,s individual medical history, risks, and concern level about breast ... as a guide and not as something fixed in concrete," ...
... , MIAMI, Nov. 19 Astor ... a Healthcare Portfolio Analyst with Citadel Investment Group. ... the investment bank continues to experience robust activity in ... Seth Zalkin, Managing Partner of Astor Group. , As ...
... a bill has been introduced in the Senate, USAction today ... to allow debate to begin so that the country can ... for all. , "Majority Leader Reid has demonstrated principled leadership ... Charney. "Now it,s time for every member of the Democratic ...
... , CARDIFF, Calif., Nov. 19 Jedi Mind, ... ), a thought-controlled and mind-controlled gaming and medical applications Company, ... the Company, new products coming out and the airing of ... Headline News. , The Company is working on multiple ...
Cached Medicine News:Health News:Preventing H1N1 spread to health care workers: Dilemma, debate and confusion 2Health News:Breaking Through the Mammography Controversy 2Health News:Astor Group Expands Healthcare Practice With Hiring of Chris Dimitropoulos 2Health News:60 Votes: Democratic Caucus Must Move Forward With Promise of Quality, Affordable Health Care for All With a Public Insurance Option 2Health News:Thought-Controlled Game; Jedi Mind, Inc. Provides Update on Progress 2
... their eyes for granted. Like the ... need proper nutrition and care to ... as you age. In fact, research ... maintaining and preserving eye health for ...
Expert QC data management solution...
The Vision Premier software features advanced,capabilities, including automatic categorization,of beats, tachogram review and full-disclosure,viewing, providing the tools needed for even,the ...
... The OmniPod: a small, lightweight self-adhesive insulin ... directly on your body for up to three ... personalized doses of insulin into your body through ... on instructions that you program into its wireless ...
Medicine Products: