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Beike Biotechnology Study Suggests Adult Stem Cells Show Promise,for Peripheral Vascular Disease

cers improved or healed in 46 (86.8%) of the 53 patients, while 25 of the 48 (47.9%) patients with limb gangrene remained steady or improved. Angiography (an X-ray) before treatment, and at 12 weeks after treatment, was performed in 10 of the patients and showed formation of new collateral vessels.

The patients had no severe adverse effects or complications related to cell transplantation.

"These preliminary results, while encouraging, must be further researched in future controlled studies and reinforced by separate studies by other laboratories," said Yang Xiao Feng, Director of the Stem Cell Program for Vascular Diseases at Shenyang 463 Hospital.

The study followed previous studies done in the laboratory and pre- clinical work done in rabbits.

"There is evidence demonstrating significant improvement in the quality of life of patients receiving the treatment, including formation of new collateral vessels," said Sean Hu, Chairman of Beike Biotechnology group. "We are now working to collaborate with institutions in the U.S. to further substantiate this and other studies including those we are doing for neurological diseases using umbilical cord stem cells."

In 2006, Beike Biotechnology completed two studies involving eight patients with ALS. Two papers were published in the Journal of Zhenghou University of Medical Science. The first observed the effect of transplantation of umbilical cord blood mesenchymal stem cells (UCB-MSCs) on glutamate (Glu) levels in plasma and CSF of amyotrophic lateral sclerosis patients and the second observed the effect of umbilical cord blood mesenchymal stem cell transplantation on nervous system function of ALS patients.

About Shenzhen Biotech Co., Ltd.

Beike is a leading biotechnology company founded with capital from Beijing University, Hong Kong University of Science and Technology and Shenzhen City Hall. It is also supported with funds from the China State National Fund. The research
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