Navigation Links
Basilea Reports Positive Re-treatment Results from a Second Phase,III Trial of Alitretinoin for Patients with Severe Chronic Hand,Eczema

in an open-label fashion for another 12 to 24 weeks. Forty-seven percent (47%) achieved a response as defined by clear or almost clear hands. These results further confirm the efficacy of alitretinoin in patients with CHE refractory to topical therapy.

Alitretinoin was generally well tolerated with a safety profile similar to that reported in previous phase II and phase III clinical studies. The most frequent adverse events were headache and blood lipid elevations.

Dr. Anthony Man, CEO of Basilea said, "Because of the relapsing nature of Chronic Hand Eczema it was important for patients and treating physicians that we further characterize the safety and efficacy of more than one treatment course of alitretinoin. These trial results confirm that alitretinoin is an effective treatment for severe refractory Chronic Hand Eczema. Alitretinoin has the potential to be integrated into pragmatic re-treatment algorithms for these chronically affected patients who have limited treatment options."

About Chronic Hand Eczema (CHE) Hand eczema is a common skin disease and is often chronic and relapsing. It is estimated to affect up to 10% of the general population. The more severe, chronic form of the condition is thought to affect up to 7% of these patients, many of whom do not respond, or no longer respond to topical corticosteroids. Basilea estimates there are at least one million patients in Europe and North America with refractory severe CHE for which currently no approved, effective pharmaceutical treatment is available.

For the patient, severe CHE can be a frustrating and debilitating disease. Patients often suffer for years from erythema, blisters, vesicles, scaling and fissures which can cause chronic pain and functional impairment of the hands. Studies suggest these patients have a significantly reduced quality of life and the majority experience social or emotional distress and sleep disorders. It is reported that up to 20% of sufferers have
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. Efficacy and Safety Profile of Basileas Alitretinoin for Severe Refractory Chronic Hand Eczema Confirmed by Data Shown at European Dermatology Congress
2. Scientific Results Presented At ECCMID Demonstrate Well- Differentiated Profile of Basileas Two Phase III Anti- infective Compounds
3. Corgenix Reports New Clinical Data Correlating AtherOx Technology With Vascular Disease
4. Cobalis Reports Phase III Trial Results for PreHistin in Seasonal Allergic Rhinitis
5. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
6. Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis
7. Cytokinetics Reports Additional Clinical Trials Data for Ispinesib
8. The European Myeloma Platform Reports New Survival data for Revlimid Presented at the International Myeloma Workshop in Greece
9. Cytochroma Reports Positive Phase I Clinical Data for CTA018 Injection
10. Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension
11. Columbia Laboratories Reports Positive Results from Multi-dose Pharmacokinetic Study of Vaginally-administered Lidocaine
Post Your Comments:
(Date:10/20/2014)... Lpath, Inc. (NASDAQ: LPTN ... official notification from the European Patent Office that ... supporting its iSONEP™ and ASONEP™ programs. ... 2087002, claims compositions of matter related to sonepcizumab, ... iSONEP and ASONEP. Sonepcizumab is an antibody that ...
(Date:10/19/2014)... 20, 2014 Shire plc (LSE: SHP, NASDAQ: ... Chief Financial Officer (CFO), has notified the Board of Directors of ... a new career opportunity as CFO of Severn Trent plc.  James ... company will commence a search for a new CFO immediately. ... has helped build and lead a high-quality finance team at Shire. ...
(Date:10/17/2014)... Oct. 17, 2014 With the recent ... function has come across several challenges in creating ... managing globalization.  The Medical ... dedicated to providing benchmarking and best practices across ... is a service composed of three stages: 1) ...
Breaking Medicine Technology:Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 2Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 3Lpath Granted Key European Patent Related to iSONEP and ASONEP Programs 4Interim Chief Financial Officer James Bowling to Step Down 2Interim Chief Financial Officer James Bowling to Step Down 3Interim Chief Financial Officer James Bowling to Step Down 4Early Key Findings from the Medical Affairs Consortium Research 2
... ROSA, Calif., Feb. 14, 2011 / PRNewswire/ ... closed a $22 million Series D financing round led ... round were Split Rock Partners, Legacy Life Sciences, EDF ... and Asset Management Partners.  In connection with the financing, ...
... (Nasdaq: DYNT ) today announced results for its ... for the quarter ended December 31, 2010, were $8,199,347, compared ... for the six months ended December 31, 2010, were $16,118,635, ... year. Net income for the quarter ended ...
Cached Medicine Technology:Sonoma Orthopedic Products® Closes $22 Million Series D Financing 2Dynatronics Announces Fiscal Second Quarter Results 2Dynatronics Announces Fiscal Second Quarter Results 3Dynatronics Announces Fiscal Second Quarter Results 4
(Date:10/20/2014)... 2014 Punzoné , the first line ... has a lot to celebrate this month. October marks Italian ... achievements and contributions of Americans of Italian heritage and Italians ... today it shares its favorite Italian cocktails and encourages everyone ... - even if it is only in a glass. ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 Hastings and ... 30 years of service throughout the greater Phoenix area ... legal representation with regard to catastrophic automobile accidents. Statistics ... the country and throughout Arizona. As such, Hastings and ... for legal representation for those who have been injured ...
(Date:10/19/2014)... NATIONS, New York (PRWEB) October 19, 2014 ... United Nations Population Fund, welcomes news of a ceasefire ... of the more than 200 girls who were kidnapped ... "These girls have languished in captivity long enough, and ... families, schools and communities," stated Dr. Osotimehin. , "We ...
(Date:10/19/2014)... October 20, 2014 Recently, Top10BestSEOHosting.com ... announced that JustHost, GoDaddy and HostMonster are the ... VPS (Virtual Private Server) is the method of ... each of which has the appearance and capabilities ... is why the site pays close attention to ...
(Date:10/19/2014)... Charlotte, NC (PRWEB) October 19, 2014 ... muscle building program has just been released to ... throughout the online body building and fitness community. ... the attention of DietsAndFitnessGuides.com's Vin Delmonico prompting an ... the experience of hitting what is commonly known ...
Breaking Medicine News(10 mins):Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 2Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 3Health News:Celebrate Italian Heritage Month With Authentic Cocktails from Punzoné: The Only Ultra Premium Line of Organic Imported Italian Vodka 4Health News:Hastings And Hastings Reports Record Demand In 2014 For Legal Representation With Regard To Catastrophic Automobile Accidents 2Health News:Hastings And Hastings Reports Record Demand In 2014 For Legal Representation With Regard To Catastrophic Automobile Accidents 3Health News:The Best VPS Hosting Suppliers In The Market Unveiled By Top10BestSEOHosting.com 2Health News:Visual Impact Frequency Training Review: Rusty Moore's Latest Fitness Guide Released 2
... , ... will be Offered Initially to the Academic and Research Communities , ... (PRWEB) -- Ziosoft®, Inc. a leader ... basic 2D/3D software free to the academic and research communities. The Windows®-based software ...
... ... in providing proven, non-surgical relief to millions of sufferers. , ... Dallas, TX (PRWEB) November 24, 2009 -- ... Shoulder Syndrome Diagnosis & Treatment seminar dates today. The three-day training seminars begin ...
... , SAN DIEGO, Nov. 24 US Farms, Inc., (Pink ... products is pleased to announce it has received formal certification ... Juice product. , Yan Skwara, CEO of ... that we have completed the certification process with the American ...
... , , 2009 ... New Transfer Agent, MEDICA 2009 , WESTON, Fla., Nov. 24 ... pleased to make available a current corporate update. , Since filing ... diligent in accomplishing additional goals, which are all part of a ...
... , , BATTLE CREEK, Mich., Nov. 24 ... and CEO of the W.K. Kellogg Foundation: , The W.K. ... need to comprehensively and substantially strengthen oral health care for ... of health reform represents a high water mark for oral ...
... behind reasoning that testing less is OK , TUESDAY, Nov. ... been upended in the past two weeks. , Not only ... the age at which it recommends women get their first ... Obstetrics and Gynecologists (ACOG) decided that adolescents should be spared ...
Cached Medicine News:Health News:Ziosoft Releases Free zioTerm Basic 2D/3D Software Application 2Health News:OTZ Announces 2010 Frozen Shoulder Syndrome Seminar Schedule 2Health News:OTZ Announces 2010 Frozen Shoulder Syndrome Seminar Schedule 3Health News:US Farms, Inc. Receives American Vegetarian Association Certification Approval for Aloe365(TM) Juice Product 2Health News:American Scientific Resources Inc. Issues Corporate Update 2Health News:American Scientific Resources Inc. Issues Corporate Update 3Health News:Statement of Support: Strengthening Oral Health Care is Key Part of Health Reform 2Health News:Recent Cancer Screening Changes Leave Many Confused 2Health News:Recent Cancer Screening Changes Leave Many Confused 3Health News:Recent Cancer Screening Changes Leave Many Confused 4
The Biopette E has a comfortable, ergonomic design. Fully motorized piston drive. Virtually eliminates pipetting forces. User-friendly operator interface. Simple, precise volume setting. Rechargelabl...
... The total ergonomic solution and best ... Soft, feather touch action and ultra ... strain, Stress-free tip ejection with long, ... easy volume identification, Accepts universal tips ...
... Electronic Pipette is ideal for all liquid ... display, ergonomically-placed operating buttons, and various dispensing ... and diluting make this a lab favorite. ... a manual pipette without any adverse effects ...
... in liquid handling, we are proud to ... that combines simplicity, comfort and functionality in ... the results of recent independent ergonomics studies, ... gives you the power to reach the ...
Medicine Products: