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Avid Announces Results of AV-1 Molecular Imaging Agent for,Alzheimer's Disease Presented at AD/PD Meeting

o develop and market certain of the Avid PET molecular imaging agents known as 18F-stilbenes for Alzheimer's disease. Avid, in collaboration with Dr. Hank Kung of the University of Pennsylvania, also continues its research and development of other new B-amyloid molecular imaging agents; two of which have now entered IND studies. Avid has also initiated an IND study of a new 18F-PET compound for imaging the vesicular monoamine transporter (VMAT-2) which is implicated in diseases involving dopaminergic degeneration such as Parkinson's disease (PD) and Dementia with Lewy Bodies (DLB). The VMAT-2 imaging program has grown out of a close collaboration with the University of Michigan as well as the University of Pennsylvania. Avid has also begun a research program on imaging B- cells of the pancreas, as a marker of the onset and progression of diabetes mellitus. For more information, visit www.avidrp.com.

About Alzheimer's Disease

According to the Alzheimer's Association (www.alz.org) there are an estimated 4.5 million people in the United States alone who have Alzheimer's disease. The number of people with Alzheimer's disease is expected to grow - by 2050 the number of individuals with Alzheimer's could range from 11.3 million to 16 million. People with Alzheimer's disease typically experience a progression of symptoms resulting from the underlying nerve cell degeneration that takes place in Alzheimer's disease. Nerve cell damage typically begins with cells involved in learning and memory and later extends to cells that control every aspect of thinking, judgment, and behavior. According to a report commissioned by the Alzheimer's Association (www.alz.org/AboutAD/statistics.asp), Alzheimer's disease costs American businesses $61 billion a year. Of that figure, $24.6 billion covers Alzheimer's health care and $36.5 billion covers costs related to caregivers of individuals with Alzheimer's disease, including lost productivity, absenteeism and worker replacemen
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