Navigation Links
Avexa Reports Positive Phase IIb Result

und 1.4 million people in North America and around 2.2 million people in Europe have HIV.

Once on therapy, patients with HIV will typically take a minimum of 3 drugs daily in combination. This may increase as a patient progresses into 2nd and 3rd line therapy or into salvage therapy, when patients develop what is commonly referred to as AIDS. Second line patients are defined as patients who show resistance to at least one class of HIV drugs, while 3rd line and salvage patients typically have resistance to multiple drugs and drug classes. Avexa aims to position ATC as the NRTI of choice for treatment of patients in 2nd and 3rd line therapy and salvage therapy, as well as the growing number of treatment naive patients presenting with HIV virus resistant to current front line therapies. In 2005 HIV drugs generated sales globally of USD $6.6 billion, with NRTIs representing greater than 50% of the overall market.

Avexa Limited is a Melbourne-based biotechnology company with a focus on research and development of drugs for the treatment of infectious diseases, in particular diseases which have a significant unmet medical need. Avexa has dedicated resources and funding for key projects including antiviral drugs for HIV and an antibiotic alternative for antibiotic-resistant bacterial infections. The Company's lead program is apricitabine (ATC) which has recently successfully completed the 21 day dosing of its Phase IIb trial. The Company continues to progress ATC towards Phase III trials.

Technical Data

Trial Design

AVX-201 is a randomised, double blind study of two doses of ATC compared to lamivudine (3TC) in treatment-experienced HIV-1 infected patients with the M184V mutation. Patients were randomised to receive 600mg or 800mg ATC twice daily, or 3TC twice daily, for 21 days, in a blinded fashion. The primary endpoint of the study is the change in the amount of virus in the blood (viral load) after 21 days treatment.

After day 2
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Avexas Apricitabine Clinical Trial Update
2. Corgenix Reports New Clinical Data Correlating AtherOx Technology With Vascular Disease
3. Cobalis Reports Phase III Trial Results for PreHistin in Seasonal Allergic Rhinitis
4. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
5. Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis
6. Cytokinetics Reports Additional Clinical Trials Data for Ispinesib
7. The European Myeloma Platform Reports New Survival data for Revlimid Presented at the International Myeloma Workshop in Greece
8. Cytochroma Reports Positive Phase I Clinical Data for CTA018 Injection
9. Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension
10. Columbia Laboratories Reports Positive Results from Multi-dose Pharmacokinetic Study of Vaginally-administered Lidocaine
11. CytRx Reports Promising Data from Its Open-Label Extension Clinical Trial of Arimoclomol in ALS
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Avexa Reports Positive Phase IIb Result
(Date:8/21/2014)... Aug. 21, 2014 /CNW/ - The Canadian Epilepsy Alliance (CEA) ... series designed to educate children about the most common neurological ... Medikidz Explain Epilepsy comic series tells a fictional story ... middle school while living with epilepsy. "Despite ... is still so much misinformation and lack of awareness out ...
(Date:8/21/2014)... 2014 /PRNewswire-iReach/ -- Inc. magazine today ... third straight year, No. 349 in Health on ... of the nation,s fastest-growing private companies. The list ... important segment of the economy—America,s independent entrepreneurs. Companies ... LinkedIn, Zillow, and many other well-known names gained ...
(Date:8/21/2014)... , Aug. 21, 2014 /PRNewswire-iReach/ -- ScriptPro ... Alliance (HITRUST) under its Common Security Framework (CSF). ... Security and Privacy Manager, "We appreciate this rigorous, ... of commitment that this certification signifies. Our business ... ABOUT THE CSF CERTIFICATION PROCESS: ScriptPro,s internal ...
Breaking Medicine Technology:Action Heroes Harness Powers to Educate Children About Epilepsy 2Action Heroes Harness Powers to Educate Children About Epilepsy 3Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 3ScriptPro Achieves HITRUST Certification 2
(Date:8/23/2014)... New York (PRWEB) August 23, 2014 ... ) filed on behalf of individuals who ... Conserve hip replacement line continue to move forward ... Georgia, Bernstein Liebhard LLP reports. According to an ... a bellwether trial program that would allow the ...
(Date:8/23/2014)... 23, 2014 Professional kitchen employees, prospective ... aid in preparing for Food Safety Certification exams thanks ... by Dynamic Path. , Dynamic Path announced the release ... more than 200 review questions for culinary industry students ... to cover requirements of the ServSafe® Food Safety Certification, ...
(Date:8/23/2014)... Teen drug and alcohol abuse is a ... Wilmington, NC. Substance abuse can happen to people of ... and alcohol dependency in higher numbers than ever before. ... abuse, but don’t know where to find professional youth ... a challenge because most treatment options are designed for ...
(Date:8/22/2014)... 2014 Deep Research Report on ... in-depth research report on the Glucose Meter market. ... Glucose Meter definition, classification, application, and industry chain ... covers the international market analysis, including domestic market ... environment & economic situation analysis. The report on ...
(Date:8/22/2014)... 23, 2014 Top 10 Best ... web hosting companies and highly recommended FatCow ( ... The manager of Top 10 Best SEO Hosting ... dedicated server hosting supplier. Actually, these companies have ... speed and customer support. People can get the ...
Breaking Medicine News(10 mins):Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 2Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 3Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 4Health News:Food Handler Safety Certification Made Easy with Dynamic Path 2Health News:Troubled Teens Wilmington Helpline Guides Adolescents to the Path of Recovery 2Health News:Glucose Meter Industry Global (Europe, Asia, NA, ROW) Analysis Now Available at ReportsnReports.com 2Health News:Glucose Meter Industry Global (Europe, Asia, NA, ROW) Analysis Now Available at ReportsnReports.com 3Health News:FatCow Reviews Released by Top10BestSEOHosting.com 2
... (Nasdaq: CSCX ), a global leader in ... today that it will release its fourth quarter 2008 ... market close. The Company has scheduled a conference call ... During the call, Cardiac Science management will discuss ...
... (LSE:MSY), the global,application software and services company, today announces that ... SWIFTReady Trade Services,Utility (TSU) 2009 label. , ... this when the,SWIFTNet TSU service came into existence in April ... again in 2008. , The TSU, ...
... Friendly and Green" awards movement, Allstar Awards of Placentia, California, has ... to promote environmentally safe awards as an alternative to the traditional ... ... -- Striving to be at the forefront of the "Eco Friendly ...
... Wish to grant its 15,000th wish this summer , ... Pickering, ON, ... the ages of three and 17 are diagnosed with a life-threatening illness. ... wish, thanks to the efforts of The Children,s Wish Foundation of ...
... March 2, 2009 (Oakland, Calif.) Drinking one glass of ... by 56 percent, according to a new study by the ... Gastroenterology . Barrett,s Esophagus is a precursor to esophageal ... that,s jumped 500 percent in the last 30 years. ...
... of Americans are losing sleep over the state of ... to a new poll released today by the National ... is associated with unhealthy lifestyles and negatively impacts health ... striking disparities in the sleep patterns, health habits and ...
Cached Medicine News:Health News:Cardiac Science Schedules Fourth Quarter Earnings Release and Announces Conference Call 2Health News:Misys Wins SWIFTReady TSU 2009 Accreditation for Third Year Running 2Health News:Misys Wins SWIFTReady TSU 2009 Accreditation for Third Year Running 3Health News:Allstar Awards Announces its New Ecologically Friendly Product Website 2Health News:Allstar Awards Announces its New Ecologically Friendly Product Website 3Health News:Children's Wish, Canada's National Wish Granting Foundation Celebrates 25 Years 2Health News:Children's Wish, Canada's National Wish Granting Foundation Celebrates 25 Years 3Health News:Drinking wine lowers risk of Barrett's esophagus, precursor to nation's fastest growing cancer 2Health News:Drinking wine lowers risk of Barrett's esophagus, precursor to nation's fastest growing cancer 3Health News:One-third of Americans lose sleep over economy 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: