Navigation Links
Avalon Pharmaceuticals Announces Positive Interim Results For,AVN944 Phase I Trial

ent samples which show a correlation of changes in gene expression in a dose dependent manner. Importantly, several of these markers display a durable, sustained stress response indicative of cancer cell death, particularly in cancer cells from AML patients. As dose levels increase the biomarkers reflect an even greater impact of AVN944 on the cancer cells. Direct markers of apoptosis are induced at these higher levels, including members of the Bcl2 gene family which play a critical role in programmed cell death. Additionally, the IMPDH enzyme is inhibited and GTP pools are also depleted for more sustained time periods in treated patients.

Potential Study Stratification Biomarker Data: Additionally we have identified a genetic signature, existing prior to drug exposure, which correlates strongly with disease stabilization in the first cycle of therapy. While still preliminary, based on a small patient sampling, this signature could be the foundation for future patient stratification strategies in phase II and III clinical trials.

Teleconference and Webcast: The company will host a conference call on Wednesday, June 20, 2007 at 8 a.m. Eastern Daylight Time to discuss the interim results of the AVN944 Phase I clinical trial. Interested investors, analysts, members of the media and the general public can listen to the call live over the Internet from the investor section of the company's Web site or by dialing the numbers listed below. A detailed PowerPoint presentation will accompany the webcast.

    Conference Call Details:


    Dial-In:           (800) 291-5365 (U.S.)

                       (617) 614-3922 (International)

                       Pass code:  74005634


    Webcast:           Please go to www.avalonrx.com, Investor Relations,

                       within 15 minutes prior to the call and select the

                       webcast link.  If listening by phone and viewing 
'"/>




Page: 1 2 3 4 5 6

Related medicine technology :

1. Avalon Updates the AVN944 Phase I Hematologic Malignancies Trial
2. Avalon Pharmaceuticals to Present at the American Association for Cancer Research 2007 Annual Meeting
3. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
4. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
5. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
6. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
7. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
8. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
9. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
10. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
11. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
Post Your Comments:
(Date:7/31/2014)... Diabetes Care®, Inc. (NASDAQ: TNDM ), a medical ... reported its financial results for the quarter ended June 30, ... 2014 to the same period of 2013: , Sales ... , t:slim Pump shipments grew 64 percent to 2,235 pumps ... June 30, 2014 to the same period of 2013: ...
(Date:7/31/2014)... , July 31, 2014  Cepheid (NASDAQ: CPHD ... the following conferences, and invited investors to participate via webcast. ... New York, NY Wednesday, August 13, ... Health Care Conference, New York, NY ... Accessing Live Webcasts To access the live webcasts ...
(Date:7/31/2014)... --  Auxilium Pharmaceuticals , Inc. (NASDAQ: AUXL ... that the Company will release results for the second ... the opening of the U.S. financial markets. The Company ... 8:30 a.m. ET to discuss results and highlights of ... be used during the call will be available on ...
Breaking Medicine Technology:Tandem Diabetes Care Reports Second Quarter 2014 Financial Results 2Tandem Diabetes Care Reports Second Quarter 2014 Financial Results 3Tandem Diabetes Care Reports Second Quarter 2014 Financial Results 4Tandem Diabetes Care Reports Second Quarter 2014 Financial Results 5Tandem Diabetes Care Reports Second Quarter 2014 Financial Results 6Cepheid to Webcast Upcoming Financial Presentations 2Auxilium Pharmaceuticals, Inc. To Announce Second Quarter 2014 Results On August 7, 2014 2Auxilium Pharmaceuticals, Inc. To Announce Second Quarter 2014 Results On August 7, 2014 3
(Date:8/1/2014)... Frontier Nursing University has been awarded ... Advanced Education Nursing Traineeship (AENT) program . This ... to 280 students over the grant period. ... increase the number of advanced education nurses trained to ... address the nurse faculty shortage that inhibits nursing schools ...
(Date:8/1/2014)... aesthetic injectable procedures have grown in popularity as more ... As Botulinum toxin generally known as BOTOX ... health professionals have emerged to perform procedures utilizing this ... Spinelli, MD from the Division of Plastic Surgery Presbyterian ... from Columbia University in New York have assessed the ...
(Date:8/1/2014)... With fast food restaurants on almost every ... processed, microwavable dinners, it is no wonder that America is ... a mere quick fix for shedding this dangerous excess fat, ... the country, get slimmer and healthier for the long term. ... and education on how to avoid obesity , they ...
(Date:8/1/2014)... 01, 2014 St. Christopher's Hospital for ... upcoming episode of Innovations with Ed Begley Jr, airing ... show times TBA. , St. Christopher's Hospital for Children ... children from birth through 21 years of age. With ... the hospital's specialties, including autism and childhood obesity. ...
(Date:8/1/2014)... 2014 For many people, forgetfulness becomes ... still within the normal range, slips that seem new ... decline. This merits a closer look, not a panic ... Harvard Men's Health Watch . , "We ... where their keys are they are on the path ...
Breaking Medicine News(10 mins):Health News:Frontier Nursing University Receives $700,000 in Scholarships for Advanced Practice Nursing and Midwifery Students 2Health News:Plastic surgeons or nurses: Who are the better injectors? 2Health News:Diet Doc Medical Weight Loss Programs Announces Diet Plans That Melt Excess Fat Rapidly While Teaching Patients How to Avoid Obesity 2Health News:Diet Doc Medical Weight Loss Programs Announces Diet Plans That Melt Excess Fat Rapidly While Teaching Patients How to Avoid Obesity 3Health News:Innovations with Ed Begley, Jr. to Feature St. Christopher's Hospital for Children in Upcoming Episode 2Health News:Innovations with Ed Begley, Jr. to Feature St. Christopher's Hospital for Children in Upcoming Episode 3Health News:Worried About Changes in Your Memory? It's Worth A Closer Look, From the August 2014 Harvard Men's Health Watch 2
... that could stop the growth of glioblastoma, a deadly form ... journal Cell , a Cell Press publication, a new ... allows them to grow and seed tumors. Importantly, normal stem ... that same dependency. "When thinking about therapeutics [targeting cancer ...
... entomology, Bradley Mullens , a professor of entomology at ... of the prestigious Entomological Society of America (ESA), ... scientific needs of entomologists and people in related disciplines. ... were elected to this honor. They will be recognized at ...
... , WEDNESDAY, July 6 (HealthDay News) -- For the millions ... to alleviate the condition has yet to be identified, a ... therapy (SMT) to other treatments such as medication, exercise or ... to be no better or worse than other options at ...
... a suitable donor for leukemia and lymphoma patients who ... that results of two clinical trials show transplant results ... comparable to fully matched tissue, thanks in large part ... post-transplant chemotherapy. The finding means that nearly all ...
... acquisition of speech, but 2 of every 1000 children ... treatment can help these children learn to speak. In ... Martin Ptok of Hannover Medical School explores whether screening ... early diagnosis, and the potential risks of newborn hearing ...
... , THURSDAY, July 7 (HealthDay News) -- Expanding ... use, improves health and well-being and reduces the ... health coverage, according to new research. "This ... and use of care for low-income adults relative ...
Cached Medicine News:Health News:To combat deadly brain cancer, target the stem cells 2Health News:UC Riverside faculty member elected fellow of Entomological Society of America 2Health News:Study Questions Chiropractic's Impact on Back Pain 2Health News:Study Questions Chiropractic's Impact on Back Pain 3Health News:Half-matched transplants widen pool of donors for leukemia and lymphoma 2Health News:Half-matched transplants widen pool of donors for leukemia and lymphoma 3Health News:Medicaid Coverage 'Substantially' Improves Access to Care: Study 2
Ballard trach care HMES and filters, tv 1500, HME with built-in flex tube...
Indications For Usage: ,Single patient use on anesthetized patients and respiratory care patients who require a breathing circuit. The product is intended to be replaced at least once every 24 hours...
... The Portex® Thermovent® T helps provide protection to ... is small and extremely lightweight making it ideal ... With a high rate of heat and moisture ... retention., ,All HMEs and filters have ISO ...
... helps provide protection to the exposed airway of ... lightweight making it ideal for active young children ... of heat and moisture recovery, it ensures patient ... and filters have ISO standard tapered ends to ...
Medicine Products: