( e Dietrich +44 (0)20 74665000 Buchanan...)Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial,Health

Brian Korb +1 646 378 2923 The Trout Group

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Details of the ASA404 trial in ovarian cancer The ASA404 trial in ovarian cancer included women with ovarian cancer that had recurred six months or more after treatment with platinum chemotherapy. Patients were randomised to receive either ASA404 plus carboplatin and paclitaxel chemotherapy or the chemotherapy drugs alone.

Endpoints measured in the trial included response (a measure of tumour shrinkage), which was assessed both by the doctors participating in the trial and by an independent analysis of patient scans; time to tumour progression (a measure of the time between treatment and the resumption of tumour growth); and survival.

Thirty-seven patients were treated in the ASA404 arm and 38 received chemotherapy alone. One patient in the ASA404 arm was excluded from the analysis of survival and one patient in the chemotherapy-alone arm was excluded from the independent analyses of response and time to tumour progression.

The data from the ovarian cancer study will be presented by Prof Hani Gabra of Imperial College, London, at the ECCO (European Cancer Conference) in Barcelona on September 26th 2007. This will be a poster presentation in the Gynaecological Cancer session (1400-1700 CET; title: Update of phase II stu
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