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Antisense Pharma: Promising Phase IIb Results of Targeted Therapy,with AP 12009 in Recurrent Anaplastic Astrocytoma

l., A Phase IIb actively controlled study with the TGF-beta 2 inhibitor AP 12009 for recurrent or refractory Anaplastic Astrocytoma, ASCO Annual Meeting, 2007, Abstract ID 2025 (2) Hau, P., et al., Results of an actively controlled Phase IIb study in recurrent or refractory glioblastoma patients with the TGF-beta 2 inhibitor AP 12009, ASCO Annual Meeting, 2007, Abstract ID 34563 (3) Hau P. and Jachimczak P. et. al., Inhibition of TGF-beta 2 with AP 12009 in recurrent malignant glioma: From preclinical to Phase I/II studies, Oligonucleotides, in press (4) Schlingensiepen K.-H., et. al., Targeted Tumor Therapy with the TGF-beta 2 antisense compound AP 12009, Cytokine Growth Factor Reviews 17 (2006): 129-139

Disclaimer This document contains forward-looking statements with respect to the future business of Antisense Pharma GmbH. By their nature, forward-looking statements and forecasts involve risks and uncertainties because they relate to events and depend on circumstances that could occur in the future. There is a number of factors that could cause actual results and developments to differ materially. Antisense Pharma GmbH disclaims any intent of obligation to update any of these forward-looking statements.

For further information please contact: Antisense Pharma GmbH Dr. Heike Specht / Public Relations Josef-Engert-Str. 9, D-93053 Regensburg Telefon: 0941-92013-0 / Fax: -29 e-mail: pr@antisense-pharma.com www.antisense-pharma.com


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