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Antipsychotic Iloperidone Results Show Favorable Akathisia Profile

of iloperidone or Vanda's other product candidates in the marketplace, a failure of the company to become or remain profitable, Vanda's inability to obtain the capital necessary to fund its research and development activities, a loss of any of the company's key scientists or management personnel, and other factors that are described in the "Risk Factors" section (Item 1A) of Vanda's annual report on Form 10-K for the year ended December 31, 2006 (File No. 000-51863). No forward-looking statements can be guaranteed and actual results may differ materially from such statements. The information in this release is provided only as of the date of this release, and Vanda undertakes no obligation to update any forward-looking statements contained in this release on account of new information, future events, or otherwise, except as required by law.

CONTACT: Chip Clark of Vanda Pharmaceuticals Inc., +1-240-599-4500,; or Quyen Lam of Ketchum Public Relations forVanda Pharmaceuticals Inc., +1-646-935-4192, chip.clark@vandapharma.com quyen.lam@ketchum.com

Web site: http://www.vandapharma.com/

Ticker Symbol: (NASDAQ-NMS:VNDA)

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