Navigation Links
Antidepressant Use May Boost Fracture Risk, From Harvard Women's,Health Watch

BOSTON, May 29, 2007 /PRNewswire-USNewswire/ -- Evidence is accumulating that depression is a risk factor for osteoporosis, reports the June 2007 issue of Harvard Women's Health Watch. A recent study found that people ages 50 and over who regularly took antidepressants called selective serotonin reuptake inhibitors (SSRIs) had double the rate of fractures as people not using such medications. Other research points to depression itself as a source of endocrine changes that can damage bone.

Whether the danger comes from depression, the drugs used to treat it, or something else, doctors are paying more attention to this association. During the 1990s, depression began to emerge as a possible cause of bone loss, rather than a result. Scientists studied women who didn't have osteoporosis symptoms or even know they had the condition. They found lower bone mineral density in those who were depressed. Moreover, the link was found in both younger women and women past menopause. Other studies have found a similar relationship, so investigators have been looking at hormones and brain chemicals potentially involved in both depression and bone loss.

Researchers working with an animal model found that depression triggers the release of noradrenaline, which interferes with bone-building cells. Moreover, they found that imipramine-a member of an older class of drugs called tricyclic antidepressants-reversed both depression and depression- induced bone loss.

It may be a long time before the depression-osteoporosis connection is fully clarified. In the meantime, Harvard Women's Health Watch suggests that you continue taking an antidepressant if you already use one; depression is a serious illness that can have profound consequences. You may also want to talk to your doctor about getting a bone density test, and make sure you get adequate calcium.


    Also in this issue:


    -- Update on treating 
IBS

    -- Driving safety and aging

    -- Simpler CPR for cardiac arrest

    -- By the way doctor: Tamoxifen versus aromatase inhibitors for

       breast cancer
 

Harvard Women's Health Watch is available from Harvard Health Publications, the publishing division of Harvard Medical School, for $24 per year. Subscribe at http://www.health.harvard.edu/women or by calling 1-877- 649-9457 (toll free).

Media: Contact Christine Junge at for a complimentary copy of the newsletter, or to receive our press releases directly. Christine_Junge@hms.harvard.edu

CONTACT: Christine Junge of Harvard Health Publications, +1-617-432-4717, Christine_Junge@hms.harvard.edu

Web site: http://www.health.harvard.edu/women//

Terms and conditions of use apply
Copyright © 2007 PR Newswire Association LLC. All rights reserved.
A United Business Media Company


'"/>




Related medicine technology :

1. Blood Levels of Paliperidone Extended-Release Tablets are Not Increased by Common Antidepressant
2. Six-Week Investigational Study In Adults With Major Depressive Disorder Evaluates The Effectiveness of Adjunctive Aripiprazole Therapy With Antidepressants
3. FDA Proposes New Warnings About Suicidal Thinking, Behavior in Young Adults Who Take Antidepressant Medications
4. CeNeRx BioPharma Announces Positive Phase I Results in First Human Trial of Third Generation RIMA Antidepressant
5. New Cardioprotective Drug Could Provide Boost For Post-Bypass Surgery Heart Health
6. Once-yearly Reclast Significantly Reduced Bone Fractures in Women with Postmenopausal Osteoporosis
7. Bipolar Disorder in Children Difficult to Diagnose, Reports the Harvard Mental Health Letter
8. FDA MedWatch: Avastin (bevacizumab) and Formation of Tracheoesophageal Fistula in a Recent Clinical Study in Patients with Limited-stage Small Cell Lung Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/12/2017)... 12, 2017   EcoVadis , the leading platform for environmental, social ... annual edition of its Global CSR Risk and Performance Index. The report ... based on Scorecard Ratings that analyzed nearly 800,000 data points across the ... ... ...
(Date:9/9/2017)... , Sept. 8, 2017 Dealmed Medical ... independent supplier of medical equipment, supplies, drugs, vaccines, and ... has entered into an agreement to acquire Vantage Medical ... based in Holtsville, New York . ... in supplying new and emerging medical practices, will operate ...
(Date:9/7/2017)... 2017 Caris Life Sciences, a leading ... promise of precision medicine, today announced results from ... its molecular profiling approach in guiding therapeutic strategies ... plus (CGP+) with Caris Molecular Intelligence ® ... molecular level, leading to more therapeutic options and ...
Breaking Medicine Technology:
(Date:9/22/2017)... ... September 22, 2017 , ... TopConsumerReviews.com recently awarded their ... that helps promote pancreatic health and regulate blood sugar levels . , ... can have negative side effects, and with the changes in today’s healthcare industry, ...
(Date:9/22/2017)... ... September 22, 2017 , ... Silicon Valley startup Enke Life ... go. Their electric toothbrushes aggressively attack oral bacteria by reducing dental plaque and ... leading edge Enke technology with a premium timeless design, they want to redefine ...
(Date:9/22/2017)... ... September 22, 2017 , ... The freshly released app ... According to Smart Mart, customers can now order vegetable, fruit, snacks, dairy, or ... can find clothing at discounted prices. Apart from this, Smart Mart has emphasized ...
(Date:9/21/2017)... ... 21, 2017 , ... With ProSlideshow Portrait from Pixel Film Studios creating a ... select from up to two layers of subject matter along with fully customizable backdrop ... Final Cut Pro X. , With ProSlideshow Portrait each user are given ...
(Date:9/21/2017)... ... September 21, 2017 , ... SABRE is raising awareness about personal safety with ... end of November. , The Chicago, Illinois, based self-defense brand has been waiting for ... the ease of taking their personal safety into their own hands. , The ads ...
Breaking Medicine News(10 mins):