Navigation Links
Analyzers Offer Point-of-Care Lipid Panels

Plasma lipids, comprised of triglycerides and cholesterols, vary with genetic predisposition, weight, diet and physical activity. All of these factors contribute to serum cholesterol and triglyceride levels and highly correlate with risk of untoward vascular and cardiac events. Perhaps no other commonly determined medical laboratory values are so much in the public eye as serum levels of good, bad, and total cholesterol, making the discussion of plasma lipid test results an opportunity for effective patient counseling and therapeutic intervention.

As with so many other diagnostic procedures that had previously been performed by clinical laboratories, kits and devices to determine LDL, HDL, total cholesterol and triglyceride levels now offer inexpensive, accurate, reimbursable, easily used and rapidly performed testing methods. Some of these products are CLIA-waived, making their use a practical enhancement of care for point-of-care settings like physician offices and clinics.

The CLIA-waived serum sample analyzers are highly flexible, incorporating glucose testing with various lipid panels and, in one device, liver function assessment as well.

Cholestech Corporation, Hayward, Calif., produces the Cholestech LDX System that uses patented, technology to measure a range of lab values from a fingerstick blood sample. Result processing takes about five minutes, according to the company.

Depending on the test cassette selected, testing can be performed for the following combinations: Total Cholesterol; Total Cholesterol and Glucose; Total Cholesterol and HDL; Total Cholesterol, HDL, and Glucose; A Lipid Panel consisting of Total Cholesterol, HDL, Triglycerides, TC/HDL ratio, estimate of LDL and VLDL, and an all-inclusive panel consisting of Total Cholesterol, HDL, Triglycerides, Glucose, TC/HDL ratio, estimate of LDL and VLDL.

Immediate liver function results are also available with the devices newly available ALT (Alanine Ami notransferase) testing capability. The tabletop analyzer unit measures 8 x 4. The device is factory calibrated, and easily accommodates software upgrades. Along with the analyzer and a starter pack of cassettes, the system includes a power supply, small printer, optics check cassette, user and procedures manual and a training video.

Polymer Technology Systems, Inc., Indianapolis, Ind., produces a 4.3 oz., battery-operated, handheld device called the Professional CardioChek P.A. This device is one of several manufactured by the company that use proprietary test strips and a reflectance photometry processor to perform a wide range of in-office tests on a single fingerstick whole blood sample. As with the Cholestech analyzer, the CardioChek product can perform a variety of tests, depending on the test strip selected. Options include a lipid panel and single testing for glucose, ketone, total cholesterol (100-400 mg/dl), HDL cholesterol (25-85 mg/dl), triglycerides (50-500 mg/dl) and calculated LDL cholesterol, all as CLIA-waived tests. The device can also measure creatinine, however, this assay is not a CLIA-waived test.

The company says that the Professional CardioChekPA meets the monitoring requirements of the National Cholesterol Education Program (NCEP) and most tests are eligible for Medicare and other insurance reimbursement.

The device features internal result storage for easy review. The accompanying thermal printer can print test results with time and date information on the spot or using data stored in the analyzers memory. The printer is capable of printing on 500-count thermal labels or thermal paper rolls.

Roche Diagnostics, Basle, Switzerland, manufactures the Accu-Chek InstantPlus Meter to perform total cholesterol (150-300 mg/dL) and glucose (20-600 mg/dL) with the same system. This simple, CLIA-waived test provides total cholesterol results in three minutes and glucose results in just 12 seconds.

As with th e other devices in this category, a fingerstick blood sample is mounted on a test strip and inserted in the analyzer. In this case, a separate strip is required for either glucose or total cholesterol testing. Three AAA batteries supply enough power for over 1000 tests. Test strips have a long shelf life and require no refrigeration.

In addition to the three devices described above, several cholesterol analyzers have been cleared for home use, and there is a range of test strips that do not require analyzer devices to test for total cholesterol.

Given the convenience and flexibility, clinical importance and interest to patients of this category of testing, it appears that point-of-care assessment of blood lipid values will continue to expand as a routine patient care activity. At the same time, the widespread competition in this field will likely yield even faster, more accurate and more comprehensive devices at even lower costs.

Related medicine technology :

1. Dade Behrings (hsCRP) Tests and BNTM Series Analyzers
2. Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results
3. Hematology Analyzers Simple, Sophisticated Technology Serving All Patients
4. Urinalysis Analyzers: Large Capabilities in Every Size Device
5. New Point-of-Care Methods to Measure Coronary and Cerebrovascular Risk

Post Your Comments:
(Date:11/24/2015)... , Nov. 24, 2015   HeartWare International, Inc ... less-invasive, miniaturized circulatory support technologies that are revolutionizing the ... and Chief Executive Officer Doug Godshall is ... Annual Healthcare Conference on December 1, 2015 at ... 1-2 in New York . ...
(Date:11/24/2015)... November 24, 2015 F1000Workspace - ... - since it was launched just six months ago. ... and authoring platform for scientists - since it was launched ... have been loaded on to F1000Workspace - a ... since it was launched just six months ago. ...
(Date:11/24/2015)... iRhythm Technologies, Inc. , a leading digital health care solutions ... participate in the 27th Annual Piper Jaffray Healthcare Conference at The ... . Kevin King , Chief Executive Officer of iRhythm, ... ET. --> --> About ... . --> iRhythm is a privately held digital ...
Breaking Medicine Technology:
(Date:11/24/2015)... ... November 25, 2015 , ... Catalent Pharma Solutions, the leading ... health and global clinical supply services, today announced that Dr. Christine Milligan, Global ... Asia Conference, to be held at the InterContinental Seoul COEX Hotel, Seoul, Republic ...
(Date:11/24/2015)... ... November 24, 2015 , ... Preparing for the LDT Regulation:, CLIA Won’t Satisfy ... , FDA has long asserted that design and manufacture of Laboratory Developed ... and do not meet the device regulations. , Come up short in an inspection ...
(Date:11/24/2015)... ... November 24, 2015 , ... ... Bolier Reactor System. Brillouin is the developer of renewable energy technologies capable of ... nuclear reactions (“LENR”), announced today that its WET™ and HHT™ Boiler System reactor ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... ... gather to share their knowledge and experiences at a live taping of the ... Ruesch Center for the Cure of Gastrointestinal Cancers 2015 Symposium at Georgetown University ...
(Date:11/24/2015)... , ... November 24, 2015 , ... Serenity Point Rehabilitation, ... series of recent video interviews with some of the staff members at their recovery ... residential treatment facility, as well as some of the things that make their recovery ...
Breaking Medicine News(10 mins):