Navigation Links
Alterations in Intestinal Serotonin in Irritable Bowel Syndrome and,Dyspepsia

ROCHESTER, MN, May 21, 2007-- Serotonin is a neurotransmitter that helps regulate intestinal functions. Mayo Clinic researchers set out to determine the role of serotonin in patients with IBS and dyspepsia. The study involved 48 females -- including individuals with IBS, individuals with dyspepsia, individuals with both IBS and dyspepsia, and healthy volunteers. Biopsies were obtained from the stomach and intestines of each patient and serotonin levels were measured. Researchers found that patients with dyspepsia had low levels of a serotonin reuptake transporter in their stomachs and high levels of a molecule that synthesizes serotonin in the small intestine.

"The results support the concept that functional disorders may be associated with altered serotonin signaling in different regions of the gut. If the data can be validated, it suggests it may someday be possible to make a diagnosis of functional disease by taking a biopsy," says Amy Foxx-Orenstein, D.O., a Mayo Clinic gastroenterologist and lead author of this study. "Mucosal markers for functional disorders might lead to earlier diagnosis and treatment, but further studies are needed."


Mayo Clinic
200 First St. S.W.
Rochester, MN 55905
(507) 284-2511

'"/>




Page: 1

Related medicine technology :

1. British Journal of Cancer Reports Preclinical Evidence of Positive Effect of Rice Bran on Intestinal Cancer
2. Phase 2a Diarrhea Predominant Irritable Bowel Syndrome Results from 2006 Presented at Digestive Disease Week in Washington, D.C.
3. New Study Demonstrates that Lubiprostone May Improve Symptom Relief Rates in Adults with Irritable Bowel Syndrome with Constipation (IBS-C)
4. Soliris Effective in PNH Patients With History of Aplastic Anemia and Myelodysplastic Syndromes
5. Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce Positive Results of Phase III Study for Milnacipran as a Treatment for Fibromyalgia Syndrome
6. Study Continues to Show Patients With Myelodysplastic Syndromes Treated With Revlimid are Living Longer and Remaining Transfusion Independent
7. Preterm Infants with Respiratory Distress Syndrome: Incidence Rates of Death when Treated with Surfactant Replacement Therapies
8. Insmed Releases Positive Results from Iplex Phase II HIV-Associated Adipose Redistribution Syndrome Clinical Study
9. XenoPort Reports Positive Top-Line Phase 3 Trial Results of XP13512 in Restless Legs Syndrome
10. Fragile X, Down Syndromes Linked to Faulty Brain Communication, Stanford Researcher Finds
11. Lipitor Provides Unprecedented Cardiovascular Risk Reductions in Diabetes Patients with Metabolic Syndrome and in Stroke Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/10/2017)... 10, 2017  NDS received FDA 510(k) clearance in May 2017 ... display stand specifically designed for endoscopy environments. An innovative secondary monitor ... clinical solution to support the improvement of patient outcomes, procedural efficiency, ... ... ...
(Date:10/7/2017)...   Provista, a proven leader in the ... purchasing power, today announced a new resource area on ... is the online home for case studies, articles ... news releases, slideshows and events. ... resources at their fingertips, viewers can also watch short ...
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare product ... training aide "cprCUBE" on Kickstarter. The device will educate ... cardiac arrests with better efficiency compared to the dated ... real-time feedback on efficacy of the compression for a ... has a goal to raise $5,000. ...
Breaking Medicine Technology:
(Date:10/13/2017)... ... October 13, 2017 , ... ... (SOP) alumni Hannah Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along ... updates for the primary prevention of cardiovascular diseases during the 15th Annual ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Many families ... However, many long-term care insurance companies have a waiver for care if the client ... elimination period, when the family pays for care, is often waived, so the benefits ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual ... in Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon ... fun run is geared towards children of all ages; it is a non-competitive, non-timed ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Agile Software Development, has been awarded a contract by the Center for Medicare ... (BPA) aims to accelerate the enterprise use of Agile methodologies in a consistent ...
(Date:10/12/2017)... ... 12, 2017 , ... First Healthcare Compliance (FHC), an industry ... a range of technology and learning solutions at the 68th Annual American Healthcare ... be held October 14–18, 2017 at the Mandalay Bay Resort in Las Vegas, ...
Breaking Medicine News(10 mins):