Navigation Links
Alpharma Presents Positive Pharmacokinetic Study Results of Its,Investigational Abuse-Deterrent, Extended-Release Opioid

orie, high-fat breakfast and took the study drug 30 minutes later. Blood samples for morphine pharmacokinetic analysis were drawn prior to dosing and at intervals from 0.5 to 168.0 hours post-dose.

The results of the pharmacokinetic analysis demonstrated, for both the fasted and fed states that the release characteristics of morphine were consistent with a sustained-release formulation and were similar to previous study results for KADIAN(R) (morphine sulfate extended-release) Capsules. Most naltrexone levels were below the assay measurement limits. Adverse events, reported in five subjects, were mild to moderate in intensity and resolved without treatment.

This study was conducted as part of Alpharma's medical development program for its abuse-deterrent morphine product, and its results were consistent with data generated in the Phase II clinical program for this product.. The company is targeting an NDA filing for its abuse-deterrent product in the first half of 2008.

Other Data Presented on KADIAN(R) Capsules

Also presented at the annual meeting were data that showed the extended- release properties of KADIAN(R) were maintained even in the presence of a significant quantity of alcohol. These results indicate that the concomitant use of tested levels of alcohol with KADIAN(R) has no significant impact on mean morphine blood levels or the timing of morphine release. Recently, the U.S. Food and Drug Administration completed a review of this data and concluded that the KADIAN(R) black box warning did not need to include any precautionary language related to alcohol.

About KADIAN(R) Capsules

KADIAN(R) capsules are an extended-release oral formulation of morphine sulfate indicated for the management of moderate-to-severe pain, when a continuous, around-the-clock opioid analgesic is needed for an extended period of time. The capsules can be taken once-daily (q24h) or twice-daily (q12h), as prescribed, to provide up to 24 hours o
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
2. European Society for Medical Oncology (ESMO) Presents Data from the Clinical Trial of MediGenes Cancer-Killing Virus in Press Conference
3. Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop
4. SemBioSys Presents Positive Insulin Data at the American Diabetes Association Conference
5. Tranzyme Pharma Presents Initial Phase IIa Data for its Novel Ghrelin Agonist, TZP-101, in Patients with Diabetic Gastroparesis
6. Novagali Pharma Presents at AACO the Results of its Pivotal Phase III Clinical Trial of Vekacia in Children Suffering From Vernal Keratoconjunctivitis
7. BioLife Solutions Presents Data on CryoStor at International Society for Cellular Therapy Annual Meeting
8. Genaera Presents Preclinical Data on Trodusquemine (MSI-1436) for the Treatment of Obesity at the American Diabetes Association 67th Scientific Session
9. Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Associations Annual Meeting
10. DiObex Presents Phase 2a Data of DIO-902 Demonstrating Trends of Improved Glycemic Control and Significant Reductions of LDL-Cholesterol and C-Reactive Protein
11. BioCryst Presents Phase I Peramivir Data at the Options for the Control of Influenza Conference
Post Your Comments:
(Date:8/21/2014)... JOSE, Calif. , Aug. 21, 2014  SI-BONE, ... medical device company that pioneered the use of the ... (MIS) device indicated for fusion of the sacroiliac (SI) ... ) published an update to its Lumbar Fusion Medical ... SI joint fusion procedure.  The policy states that the ...
(Date:8/20/2014)... N.Y. , Aug. 20, 2014 ... today announced that after months of hard work ... finished the new Snorenz formulation and package design.  ... E and B-6 back into the product due ... as longer lasting effects.  Snorenz Nighttime will also ...
(Date:8/20/2014)... The National Association of Drug Diversion ... by the real-time, pseudoephedrine (PSE) blocking system in ... Exchange (NPLEx), automatically blocks unlawful pseudoephedrine sales and ... and make arrests. Data released by NPLEx shows ... blocked the sale of more than 7,481 boxes of ...
Breaking Medicine Technology:SI-BONE, Inc. Announces Positive Coverage Decision by Priority Health 2SI-BONE, Inc. Announces Positive Coverage Decision by Priority Health 3Northstar completes the first phase of its new retail strategy and prepares to ship reformulated Snorenz with all new packaging 2Kansas's Stop-Sale System Achieves Significant Results In Battle Against Meth 2
... 19 Fox Insurance Company agreed July 9 ... for Medicare Part D prescription drug claims to the administrators ... which is currently closing claims and beginning to process payments ... in order to provide long-awaited reimbursements to independent community ...
... DEKA Medical announced today the immediate availability of the High-Powered SmartXide DOT. ... 50W, can attain irradiance of up to 250W of power with each ... CO2 laser available to aesthetic physicians. , ... "We are pleased to announce this significant advancement in CO2 ...
Cached Medicine Technology:Fox Insurance Agrees to Pay Delinquent Medicare Part D Claims After Action by Senators Baucus, Grassley, CMS and NCPA 2Fox Insurance Agrees to Pay Delinquent Medicare Part D Claims After Action by Senators Baucus, Grassley, CMS and NCPA 3Fox Insurance Agrees to Pay Delinquent Medicare Part D Claims After Action by Senators Baucus, Grassley, CMS and NCPA 4DEKA Medical Announces Immediate Availability of High Power SmartXide DOT Fractional CO2 Laser 2
(Date:8/22/2014)... 2014 The Fit Body Boot Camp World ... the premier event for fitness boot camp marketing ... marketing expert and Spike TV consultant Bedros Keuilian, the Fit ... Fit Body franchise owners. This year, a handful of non-owners ... great information from some really big names in the business,” ...
(Date:8/22/2014)... Dallas, Texas (PRWEB) August 22, 2014 ... from $297 million in 2013 to $407 million by ... 6.59%. The company’s latest report “OpportunityAnalyzer Graft-Versus-Host Disease – ... growth, which will occur over six major markets (6MM: ... will be strongest in the five European countries (5EU), ...
(Date:8/22/2014)... 22, 2014 Wounded service members, celebrities, sports ... fun as part of the 5th Annual Scarlet & Gold ... 14 at the River Landing Country Club in Wallace, NC. ... Warriors®, a national nonprofit dedicated to restoring a sense of ... service members and our military families. , The event is ...
(Date:8/22/2014)... An increasing number of mergers and ... the market. M&As provide financial assistance to smaller companies, ... the distribution channels of companies and help in increasing ... , According to the “ Global Animal Health Market ... protein-rich diet is one of the major drivers in ...
(Date:8/22/2014)... NY (PRWEB) August 22, 2014 ... Heart Health Clinics are promoting non-invasive screening, risk ... preventable risks of cardiovascular morbidity and mortality, even ... stroke, Deep Vein Thrombosis and Pulmonary Embolus, and ... are promoting painless, noninvasive screening at accredited facilities ...
Breaking Medicine News(10 mins):Health News:Fit Body Boot Camp World Conference 2014 Set To Maintain Reputation as Fitness Boot Camp Marketing Event of the Year 2Health News:Fit Body Boot Camp World Conference 2014 Set To Maintain Reputation as Fitness Boot Camp Marketing Event of the Year 3Health News:Graft-Versus-Host Disease Treatment Market Worth $409.0m by 2018 Says a New Report Available at MarketOptimizer.org 2Health News:Graft-Versus-Host Disease Treatment Market Worth $409.0m by 2018 Says a New Report Available at MarketOptimizer.org 3Health News:Graft-Versus-Host Disease Treatment Market Worth $409.0m by 2018 Says a New Report Available at MarketOptimizer.org 4Health News:Hope For The Warriors Announces Celebrity Golf Invitational Benefiting Military Families 2Health News:Hope For The Warriors Announces Celebrity Golf Invitational Benefiting Military Families 3Health News:Global Animal Health Market 2014-2018 a New Research Report Added to ReportsnReports.com 2Health News:Global Animal Health Market 2014-2018 a New Research Report Added to ReportsnReports.com 3Health News:Global Animal Health Market 2014-2018 a New Research Report Added to ReportsnReports.com 4Health News:NY Heart Health Clinics Created by Dr. David Greuner and Dr. David Luu of NYC Surgical Associates 2Health News:NY Heart Health Clinics Created by Dr. David Greuner and Dr. David Luu of NYC Surgical Associates 3
... A clinical trial in Cambodia has found it possible ... very weak immune systems and newly diagnosed tuberculosis (TB) ... treatment, rather than waiting eight weeks, as has been ... Institute of Allergy and Infectious Diseases (NIAID), part of ...
... July 22 Adult circumcision has been proposed as a ... study by the University of Pittsburgh Graduate School of ... suggests it would have a very small effect on reducing ... thought to reduce the risk of HIV transmission by removing ...
... insulin resistance and the action of diabetes drugs such ... improved medications that are more selective and safer, say ... Institute. "Our findings strongly suggest that good and ... designing second-generation drugs that focus on the newly uncovered ...
... College Park, MD (July 20, 2010) -- Eighty years ago, ... of metabolism, but the idea went out of vogue. Now, ... cancer and other common diseases. Metabolism is a highly connected ... pathways. Such parallelism can mask how genes are linked ...
... Cancer surgery wreaks havoc on a body,s immune system and ... of those who undergo surgery for tumor removal experience a ... of the body. A new clinical approach being ... the key to making cancer operations more successful. Prof. Shamgar ...
... group of patients at one of the nation,s largest ... who have previously refused colorectal cancer screening, are willing ... but not willing to pay for the exam themselves ... in the August issue of the American Journal ...
Cached Medicine News:Health News:NIH-funded study finds early HAART during TB treatment boosts survival rate in co-infected people 2Health News:Scientists find unsuspected molecular link between obesity and insulin resistance 2Health News:Scientists find unsuspected molecular link between obesity and insulin resistance 3Health News:A new drug treatment to close the window on colon cancer 2Health News:Lack of insurance coverage remains obstacle to wider colorectal cancer screening with CT colonography 2
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Medicine Products: