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Algeta Demonstrates Targeted Cancer-killing Potential of Novel,Alpha Particle Linked Antibodies in Leading Medical Journal Blood

p>Therapy with 227Th-rituximab was significantly more effective than the control radioimmunoconjugate 227Th-trastuzumab, which does not bind CD20, and the standard beta particle emitting radioimmunoconjugate for CD20-positive lymphoma, Zevalin® (90Y-tiuxetan-ibritumomab), which is marketed by Biogen-Idec.

Dr Thomas Ramdahl, President and CEO of Algeta commented: "This important paper provides more evidence of the potential of alpha particle based molecules for targeted cancer therapy. The publication follows excellent Phase II clinical data for our lead product Alpharadin (radium-223) in prostate cancer, which was published recently in the Lancet Oncology. We are working with collaborators to validate our TH-1 technology and are looking for further partnering opportunities with companies that have interesting cancer-targeting molecules that would benefit from this approach."

Reference

Targeted cancer therapy with a novel low dose rate alpha-emitting radioimmunoconjugate (2007) Dahle, J. et al. (2007)

http://bloodjournal.hematologylibrary.org/cgi/ content/abstract/blood-2007-01-066803v1

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For further information, please contact

Dr. Thomas Ramdahl, CEO +47 23 00 79 90 / +47 913 91 458 (mob) Geir Christian Melen, CFO +47 23 00 79 90 / +47 913 02 965 (mob) post@algeta.com

Dr. Mark Swallow / Helena +44 (0)207 638 9571 Galilee mark.swallow@citigatedr.co.uk Citigate Dewe Rogerson

About Algeta

Algeta ASA (www.algeta.com) is a Norwegian cancer therapeutics company built on world-leading, proprietary technology.

Algeta is developing new, targeted cancer therapeutics that harness the unique characteristics of alpha particle emitters and are pote
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