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Alexza Pharmaceuticals to Present AZ-004 (Staccato Loxapine),Clinical Data at the Annual NCDEU Meeting

PALO ALTO, Calif., June 05, 2007 /PRNewswire-FirstCall/ -- Alexza Pharmaceuticals, Inc. announced today that it will present at the 47th Annual NCDEU Meeting the results of a Phase I clinical trial of Staccato loxapine (AZ-004), which is being developed for the treatment of acute agitation in patients with schizophrenia. The annual NCDEU meeting is co-sponsored by the National Institute of Mental Health and the American Society of Clinical Psychopharmacology.

The poster presentation, "Novel inhalation technology delivers intravenous-like pharmacokinetics of loxapine in healthy volunteers" (Session 1-93), will be available for viewing at the meeting at the Mizner Center in Boca Raton, Florida on Tuesday, June 12, 2007 from 12:00 to 2:00 pm.

Alexza Pharmaceuticals is an emerging pharmaceutical company focused on the development and commercialization of novel, proprietary products for the treatment of acute and intermittent conditions. The Company's technology, the Staccato system, vaporizes unformulated drug to form a condensation aerosol that allows rapid systemic drug delivery through deep lung inhalation. The drug is quickly absorbed through the lungs into the bloodstream, providing speed of therapeutic onset that is comparable to intravenous administration, but with greater ease, patient comfort and convenience. The Company has five product candidates in clinical development; AZ-001 (Staccato prochlorperazine) for the acute treatment of migraine headaches, AZ-004 (Staccato loxapine) for the treatment of acute agitation in patients with schizophrenia, AZ-002 (Staccato alprazolam) for the acute treatment of panic attacks associated with panic disorder, AZ-003 (Staccato fentanyl) for the treatment of patients with acute pain and AZ-007 (Staccato zaleplon) for the treatment of sleep disorder in patients who have difficulty falling asleep.

CONTACT: Thomas B. King, Pesident & CEO of Alexza Pharmaceuticals, Inc.,+1-650-687-3900, tking@alexza.com

Web site: http://www.alexza.com/

Ticker Symbol: (NASDAQ-NMS:ALXA)

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