Navigation Links
Additional Efficacy Data from Satraplatin SPARC Phase 3,Investigational Trial Presented at Annual Meeting of American,Urological Association

eutropenia. Eight percent of patients in the satraplatin arm experienced grade 3 or 4 gastrointestinal toxicities, including nausea (1.3%), vomiting (1.6%), diarrhea (2.1%) and constipation (2.1%). Five percent or less of patients in the satraplatin arm experienced grade 3 or 4 fatigue, grade 3 or 4 infections and pulmonary/respiratory grade 3 or 4 toxicities.

About Satraplatin

Satraplatin, an investigational drug, is a member of the platinum family of compounds. Platinum-based drugs are a critical part of modern chemotherapy treatments and are used to treat a wide variety of cancers. All platinum drugs currently on the market require intravenous administration. Satraplatin is an orally bioavailable compound and is given as capsules that patients can take at home.

A Phase 3 registrational trial, called SPARC, is evaluating satraplatin plus prednisone versus placebo plus prednisone in 950 patients with hormone-refractory prostate cancer whose prior chemotherapy has failed. Data from the trial on progression-free survival and on safety have been presented at recent medical conferences. In accordance with the recommendation of the independent Data Monitoring Board for the SPARC trial, patients who have not progressed continue to be treated and all patients will be followed for overall survival.

GPC Biotech has a co-development and license agreement with Pharmion GmbH, a wholly owned subsidiary of Pharmion Corporation, under which Pharmion has been granted exclusive commercialization rights to satraplatin for Europe and certain other territories. Pharmion has indicated it expects to complete the Marketing Authorization Application (MAA) for satraplatin for Europe in the second quarter of 2007. GPC Biotech in-licensed satraplatin from Spectrum Pharmaceuticals, Inc. in 2002.

Satraplatin has been studied in clinical trials involving a range of tumors. Trials evaluating the effects of satraplatin in combination with radiation therapy, in c
'"/>




Page: 1 2 3 4 5 6

Related medicine technology :

1. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
2. Cytokinetics Reports Additional Clinical Trials Data for Ispinesib
3. Additional Data on CombinatoRx Drug Candidates CRx-102 and CRx-139 Presented at EULAR
4. Further Statistical Analysis of the Recent Phase III trial on Lead Product M6G Shows Additional Benefits
5. Novel Mechanism Insights and Additional Data on CombinatoRx Drug Candidates to Be Presented at Upcoming EULAR Meeting
6. Elixir Pharmaceuticals Presents Additional Preclinical Data Demonstrating the Potential of Ghrelin Antagonism to Regulate Metabolism, Body Weight and Glycemic Control
7. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
8. Cell Genesys Reports Additional Data From Phase 2 Clinical Trial of GVAX Immunotherapy for Pancreatic Cancer
9. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
10. New Study Results Provide Additional Data about Short- and Long-Term Use of Desvenlafaxine Succinate in the Treatment of Adults with Major Depressive Disorder
11. PTC Therapeutics Announces Additional Positive Interim Phase 2 Results of PTC124 in Duchenne Muscular Dystrophy
Post Your Comments:
(Date:8/21/2014)... /PRNewswire-iReach/ -- Inc. magazine today ranked ... straight year, No. 349 in Health on its ... the nation,s fastest-growing private companies. The list represents ... segment of the economy—America,s independent entrepreneurs. Companies such ... Zillow, and many other well-known names gained early ...
(Date:8/21/2014)... NEW YORK , August 21, 2014 /PRNewswire/ ... its Israeli subsidiary, BreedIT Ltd., the exclusive worldwide ... solutions software for plant breeders and researchers, today ... Ltd., a joint venture with Seach Ltd, a ... was formed to research and develop new breeds ...
(Date:8/21/2014)... Aug. 21, 2014  AliveCor, Inc. announced ... Administration (FDA) has granted the company clearance ... (AFib), the most common form of cardiac ... detects if patients are experiencing AFib through ... mobile phone based AliveCor® Heart Monitor, so ...
Breaking Medicine Technology:Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 2Carolina's HME Named for Third Straight Year to Inc. Magazine's List of America's Fastest-Growing Private Companies--the Inc. 5000 3BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 2BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 3BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 4AliveCor Receives First FDA Clearance to Detect a Serious Heart Condition in an ECG on a Mobile Device 2
... 14, 2010 Patients and doctors no longer have ... now that Advanced Radiology has introduced Baltimore area,s first ... boreless magnet is a major advancement for patients who ... to claustrophobia or height/weight limitations.  Claustrophobic patients can avoid ...
... 14, 2010 The Dr. Paul Janssen Award ... for nominations. This prestigious award recognizes individuals whose ... to make, significant transformational contributions toward the improvement ... www.pauljanssenaward.com and will be accepted until February ...
Cached Medicine Technology:Advanced Radiology Introduces Baltimore's First 1.2T High Field Open MRI 2Dr. Paul Janssen Award for Biomedical Research Issues Call for Nominations 2Dr. Paul Janssen Award for Biomedical Research Issues Call for Nominations 3
(Date:8/21/2014)... chronic kidney disease patients may be a strong indicator ... in the Journal of the American Society of ... Hopkins Bloomberg School of Public Health assert that coronary ... atherosclerosis in predicting the risk of heart disease among ... all patients with chronic kidney disease (CKD) die from ...
(Date:8/21/2014)... 21, 2014 Pulmonary Hypertension Association ... Education Forum for PH patients and families to ... Pulmonary Hypertension Association – the country’s leading ... to prevent and cure pulmonary hypertension (PH) – ... functioning of the heart and can lead right ...
(Date:8/21/2014)... DURHAM, NC -- Researchers have pinpointed the environmental source ... in Southern California for decades. It literally grows on ... project of a 13-year-old girl, who spent the summer ... Angeles hardest hit by infections of the fungus named ... Cryptococcus , which encompasses a number of species ...
(Date:8/21/2014)... -- Black mothers are less likely than white moms ... why: Hospitals in neighborhoods with many black residents do ... more white residents, a U.S. government study finds. ... in medical centers where the black population is higher ... Control and Prevention reported Thursday. These practices include ...
(Date:8/21/2014)... Aug. 21, 2014 (HealthDay News) -- Among seniors, dimming ... The study involved more than 2,500 people, aged 65 ... study and again two, six and eight years later. ... the person,s risk of death during the study period, the ... effect, researchers led by Sharon Christ of Purdue University in ...
Breaking Medicine News(10 mins):Health News:Measuring calcium buildup to predict heart disease in those with chronic kidney disease 2Health News:Pulmonary Hypertension Association Goes On the Road to Houston With an Education Forum for PH Patients and Families to Help Fight Rare Lung Disease 2Health News:Pulmonary Hypertension Association Goes On the Road to Houston With an Education Forum for PH Patients and Families to Help Fight Rare Lung Disease 3Health News:Fungus deadly to AIDS patients found to grow on trees 2Health News:Racial Disparities in Breast-Feeding May Start With Hospitals, Study Suggests 2Health News:Failing Vision Tied to Shorter Lifespans for Seniors 2
... Growth rate of ... ... insight and analytics firm, today reported that the number of Medicaid-subsidized inpatient hospital stays originating ... rate of all inpatient hospital stays that began in the hospital outpatient ER was less ...
... pathway , TUESDAY, March 30 (HealthDay News) -- A ... diabetes has been discovered by U.S. researchers. , The ... fails because of obesity. Artificial activation of this pathway ... according to the report published online March 28 ...
... ... is a major key for returning us back to our natural state as a vibrant ... (PRWEB) ... Medicine and an Industrial Toxicologist, has dedicated a quarter of a century to discovering the ...
... study, anxieties over dying rose among older people cared ... News) -- Having many supportive relatives actually increases the ... according to British researchers. , The finding runs counter ... family caregivers eases the fear of death. It also ...
... Researchers say a square a day could lead to fewer heart ... those who believe in the Easter bunny (or at least in ... one small square of chocolate a day might help lower your ... analyzing the diet and health habits of 19,357 people, aged 35 ...
... lung cancer per year in Germany are due to ... in the current edition of Deutsches rzteblatt International ... and his coauthors ( Dtsch Arztebl Int 2010; ... the results of relevant studies, the recently published S1 ...
Cached Medicine News:Health News:Novel Method Eyed for Normalizing Blood Sugar 2Health News:Scientist, Dr Staninger, Unlocks the Mystery of Morgellons Disease 2Health News:Scientist, Dr Staninger, Unlocks the Mystery of Morgellons Disease 3Health News:More Family Support Can Raise Fears For Some Elderly 2Health News:A Little Chocolate May Do the Heart Good 2
Ties improve torso fit and transfer weight to waist and hips. Ties are 1"W cotton woven for flexibility and sewn at an angle across the full width of the two back sections for durability....
Use this workhorse apron where 360 of protection from direct and scatter radiation is required....
Mini Aprons are half aprons with an easy-on, easy-off Velcro-style closure that fastens securely in seconds. Color-coded sizes for easy identification. Offers 0.5 mm Pb equivalent protection....
... Bio-Rad offers the Pathfinder Rotavirus EIA, ... infection which can significantly aid in patient ... Direct Antigen Detection System is for the ... This assay combines the specificity and ...
Medicine Products: