Navigation Links
Additional Data From Satraplatin SPARC Phase 3 Trial Presented at,European Association of Urology Congress

Patients treated with Satraplatin Demonstrated Statistically Significant Improvement in Pain Response and PSA Response Rates

BERLIN, March 22, 2007 /PRNewswire-FirstCall/ -- Pharmion Corporation and GPC Biotech AG today announced additional data from the double-blind, randomized satraplatin Phase 3 registrational trial, the SPARC trial (Satraplatin and Prednisone Against Refractory Cancer) which were presented today at the 22nd Annual European Association of Urology Congress in Berlin, Germany. The trial is evaluating satraplatin plus prednisone versus placebo plus prednisone in 950 patients with hormone-refractory prostate cancer (HRPC) who have failed prior chemotherapy.

"Second-line chemotherapy for patients with hormone-refractory prostate cancer represents a true unmet medical need and the encouraging satraplatin data suggest that for the first time, we may have a treatment option for these patients with advanced disease," said Professor Fred Witjes, Professor of Urology, Academisch Ziekenhuis, Nijmegen, The Netherlands. "In particular, the very impressive pain and PSA response rates seen in the SPARC study, especially considering the fact that all these patients were progressive after hormones and chemotherapy, further suggest satraplatin's active anti-tumor effect in this patient population."

Data presented today from the SPARC study showed that pain response rates for patients treated with satraplatin were statistically significantly superior compared to the pain response rates for those patients in the comparator arm. Pain response rates were 24.2 percent for the satraplatin plus prednisone arm compared with 13.8 percent for the placebo arm (p=0.005).

Pain response was assessed by patients using a weekly present pain intensity (PPI) and analgesic score. The PPI score was defined according to the McGill-Melzack questionnaire with 0 = no pain, 1 = mild pain, 2 = discomforting pain, 3
'"/>




Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
2. Cytokinetics Reports Additional Clinical Trials Data for Ispinesib
3. Additional Data on CombinatoRx Drug Candidates CRx-102 and CRx-139 Presented at EULAR
4. Further Statistical Analysis of the Recent Phase III trial on Lead Product M6G Shows Additional Benefits
5. Novel Mechanism Insights and Additional Data on CombinatoRx Drug Candidates to Be Presented at Upcoming EULAR Meeting
6. Elixir Pharmaceuticals Presents Additional Preclinical Data Demonstrating the Potential of Ghrelin Antagonism to Regulate Metabolism, Body Weight and Glycemic Control
7. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
8. Cell Genesys Reports Additional Data From Phase 2 Clinical Trial of GVAX Immunotherapy for Pancreatic Cancer
9. Additional New Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at ASCO Annual Meeting
10. New Study Results Provide Additional Data about Short- and Long-Term Use of Desvenlafaxine Succinate in the Treatment of Adults with Major Depressive Disorder
11. Additional Efficacy Data from Satraplatin SPARC Phase 3 Investigational Trial Presented at Annual Meeting of American Urological Association
Post Your Comments:
(Date:9/30/2014)... Sept. 30, 2014  Georgia-Pacific Professional is a ... tissue for a wide range of away from ... product lines in healthcare, including hospitals, long-term care ... is introducing its healthcare products and solutions to ... the importance of infection control in the dental ...
(Date:9/30/2014)... 30, 2014 The report based ... Size, Share, Growth and Forecast, 2007 - 2017," elaborated ... USD 20.8 billion in 2012 and is further expected ... a CAGR of 7.3% from 2012 to 2017. ... health purposes, especially to prevent chronic diseases that may ...
(Date:9/30/2014)... BURLINGTON, Mass. , Sept. 30, 2014 /PRNewswire/ ... of U.S. patient-level claims data, anemic chronic kidney ... with their erythropoiesis-stimulating agent (ESA) medication. In addition, ... Janssen,s Procrit. Other key findings ... in Nephrology: An Analysis of Erythropoiesis Stimulating Agents ...
Breaking Medicine Technology:Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 3Nutraceutical Ingredient Market Will Reach USD 33.6 Billion Globally in 2018: Transparency Market Research 2Nutraceutical Ingredient Market Will Reach USD 33.6 Billion Globally in 2018: Transparency Market Research 3Nutraceutical Ingredient Market Will Reach USD 33.6 Billion Globally in 2018: Transparency Market Research 4Persistency is Low for Late-Stage Anemic CKD Non-Dialysis Patients Treated with Erythropoiesis-Stimulating Agents 2Persistency is Low for Late-Stage Anemic CKD Non-Dialysis Patients Treated with Erythropoiesis-Stimulating Agents 3
... (NYSE Amex: NBS ) ("NeoStem" or the ... cell based therapeutics development, today announced two appointments to ... Greenacre, an experienced business leader in the biopharmaceutical industry ... and joins as an additional independent director, and Dr. ...
... YORK, Dec. 8, 2011 Reportlinker.com announces ... available in its catalogue: ... http://www.reportlinker.com/p090656/Global-Gamma/Scintillation-Cameras-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Camera This report ... in US$ Thousand by the following Product ...
Cached Medicine Technology:NeoStem Appoints a Biopharmaceutical Business Leader and a Cellular Therapy Expert to its Board of Directors 2NeoStem Appoints a Biopharmaceutical Business Leader and a Cellular Therapy Expert to its Board of Directors 3NeoStem Appoints a Biopharmaceutical Business Leader and a Cellular Therapy Expert to its Board of Directors 4Global Gamma/Scintillation Cameras Industry 2Global Gamma/Scintillation Cameras Industry 3Global Gamma/Scintillation Cameras Industry 4Global Gamma/Scintillation Cameras Industry 5Global Gamma/Scintillation Cameras Industry 6Global Gamma/Scintillation Cameras Industry 7Global Gamma/Scintillation Cameras Industry 8Global Gamma/Scintillation Cameras Industry 9Global Gamma/Scintillation Cameras Industry 10Global Gamma/Scintillation Cameras Industry 11Global Gamma/Scintillation Cameras Industry 12Global Gamma/Scintillation Cameras Industry 13Global Gamma/Scintillation Cameras Industry 14Global Gamma/Scintillation Cameras Industry 15Global Gamma/Scintillation Cameras Industry 16Global Gamma/Scintillation Cameras Industry 17Global Gamma/Scintillation Cameras Industry 18Global Gamma/Scintillation Cameras Industry 19
(Date:9/30/2014)... University of Maryland-led research team has been awarded ... Institutes of Health (NIH) to develop new imaging ... our understanding of how large networks of neurons ... This knowledge will help researchers identify the precise ... behavior, like decision-making and speaking, and alterations in ...
(Date:9/30/2014)... EverStryke , the permanent match currently offered ... with a free book and class all about survival education ... an investigative review. , “Joe Marshall of SurvivalLife.com is ... preparation niche, and this product is an excellent way to ... products that Joe offers on his website to help people ...
(Date:9/30/2014)... NV (PRWEB) September 30, 2014 Elevate ... helping people perform better in and out of the gym ... memory has caught the attention of Shane Michaels, prompting an ... grind, fatigue is the reason most people simply just don’t ... that means staying focused at work, getting the motivation to ...
(Date:9/30/2014)... September 30, 2014 VisitandCare.com ... Turkey has gone up more than 79 percent in ... tourism company also reported total revenue tripled for its ... The company’s professional strategy has allowed them to partner ... designed for patient comfort and privacy — with state-of-the-art ...
(Date:9/30/2014)... 30, 2014 Hospice & Palliative ... “In Celebration” gala, honoring three outstanding individuals for ... striving to provide extraordinary and dignified comfort, care ... serious or life-limiting illness. , The event was ... NY and recognized William (Bill) J. McGuinness, Director ...
Breaking Medicine News(10 mins):Health News:UMD receives inaugural BRAIN Initiative Award 2Health News:EverStryke: Review Exposes Joe Marshall’s Permanent Match Survival Product 2Health News:Elevate: Review Exposes Blue Star Nutraceutical’s Latest Supplement for Ultimate Brain Function, Focus, and Energy 2Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 2Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 3Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 4Health News:Hospice & Palliative Care of Westchester Honors Outstanding Individuals at Annual ‘In Celebration’ Gala 2
... potentially play an important role in treating some ... diseasethe Society of Interventional Radiology has issued a ... research to determine the safety and effectiveness of ... by the Canadian Interventional Radiology Association and will ...
... treat metastatic melanoma tumors with a specific genetic signature was successful ... clinical trial. Results of the trial of PLX4032, an inhibitor ... half of all melanomas, appear in the August 26 New ... and is one of the top causes of cancer death in ...
... WEDNESDAY, Aug. 25 (HealthDay News) -- Two of the ... connection, with new research suggesting that having insulin resistance or ... plaques associated with Alzheimer,s disease. After adjusting for other ... highest levels of fasting insulin had nearly six times the ...
... , WEDNESDAY, Aug. 25 (HealthDay News) -- If you,re like millions ... to salmonella contamination has probably made you refrain from ordering "sunny ... time has passed, and you,re starting to crave an omelette. So ... your fridge or are you inviting a bout of vomiting and ...
... By Amanda Gardner HealthDay Reporter , TUESDAY, ... medications an adult might be taking for attention-deficit/hyperactivity disorder ... new research suggests. After one year, patients ... persistent symptoms better than using drugs plus relaxation exercises. ...
... Reinberg HealthDay Reporter , TUESDAY, Aug. 24 ... against the herpes virus should not worry that their ... More than 1 percent of women develop herpes simplex ... use during pregnancy of antiviral drugs such as acyclovir ...
Cached Medicine News:Health News:Society of Interventional Radiology supports research for new MS treatments 2Health News:Society of Interventional Radiology supports research for new MS treatments 3Health News:Targeted drug leads to regression of metastatic melanoma with mutated BRAF gene 2Health News:Targeted drug leads to regression of metastatic melanoma with mutated BRAF gene 3Health News:Link Between Diabetes, Alzheimer's Disease Strengthened 2Health News:Link Between Diabetes, Alzheimer's Disease Strengthened 3Health News:Link Between Diabetes, Alzheimer's Disease Strengthened 4Health News:Are The Eggs in Your Fridge Safe to Eat? 2Health News:Are The Eggs in Your Fridge Safe to Eat? 3Health News:Are The Eggs in Your Fridge Safe to Eat? 4Health News:Cognitive Therapy Helps Adults With ADHD 2Health News:Herpes Drugs Won't Raise Birth Defect Risk, Study Finds 2Health News:Herpes Drugs Won't Raise Birth Defect Risk, Study Finds 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: