Navigation Links
Actilyse (alteplase) Recommended by National Institute for Health,and Clinical Excellence for Treatment of Acute Ischaemic Stroke

have suffered an acute ischaemic stroke. This is important since acute ischaemic stroke is responsible for considerable disability and mortality worldwide and we hope that this recommendation from NICE will allow more patients with qualifying stroke in the UK to benefit from treatment with Actilyse®.”

In reaching their decision, NICE also found that the use of alteplase with best supportive care is cost effective when compared with placebo and best supportive care.1 The Nice appraisal recommends that alteplase should be used by physicians trained and experienced in the management of acute stroke and only in centres with facilities that enable it to be used in full accordance with its marketing authorisation.

While the NICE appraisal emphasises the importance of using alteplase only within 3 hours after the onset of stroke symptoms, the European Cooperative Acute Stroke Study (ECASS) III,3 in accordance with the marketing authorisation evaluates the potential efficacy and safety of using Actilyse® within a time-window of 3 to 4.5 hours in patients with acute ischaemic stroke. Results of the ongoing ECASS III trial are expected in 2008.

Notes to Editor

About Actilyse®
Stroke is a neurological emergency that can affect a specific area, or sometimes all of the brain. It can be caused by a burst blood vessel (haemorrhagic stroke) or occur when a vessel is obstructed by a blood clot (ischaemic stroke). Actilyse® (alteplase) is the first and only treatment available for acute ischaemic stroke recommended by international guidelines as a first-line treatment.4,5,6 Actilyse® is a clot-busting drug, which is injected directly into a vein. In line with the Actilyse® label, patients need to receive the medication within three hours of the onset of their stroke symptoms. Randomised placebo-controlled studies have shown that thrombolysis with Actilyse®, administered within three hours of the onset of symptoms of
'"/>




Page: 1 2 3 4 5

Related medicine technology :

1. International ENDORSE Study Shows That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE prophylaxis
2. Largest National U.S. Healthcare Facility MRSA Study Reveals Infection Rates Eight Times Greater Than Previous Estimates
3. Positive Results Prompt US National Cancer Institute to Make Glivec Available to Patients in Post-Surgical GIST Study
4. Positive Results Prompt US National Cancer Institute to Make Gleevec Available To Patients in Post-Surgical Gist Study
5. First-of-its-Kind National Report Reveals Estimated High Prevalence and Heavy Cost of Type 2 Diabetes Complications in America
6. Research Results on FluMist Presented at National Association of Pediatric Nurse Practitioners Conference
7. Protox Announces Publication in Journal of the National Cancer Institute Supporting PRX302 as Treatment for Prostatic Diseases
8. Calando Pharmaceuticals Publishes the First Non-Human Primate Study on Targeted, Systemic Delivery of siRNA in National Academy of Sciences Journal
9. Advanced Magnetics Announces Presentation of Ferumoxytol Data at the National Kidney Foundation 2007 Spring Clinical Meetings
10. Rosetta Genomics and Weizmann Institute Scientists Identify Role of microRNA in Cancer Suppression
11. Southern Research Institute to Present at the 2007 American Association For Cancer Research Annual Meeting
Post Your Comments:
(Date:12/16/2009)... -- MedSolutions ( www.medsolutions.com ), a leading provider ... new studies highlighting the dangers of excess radiation ... tests. ,, "When used properly, CT imaging ... Gregg Allen, M.D., chief medical officer of MedSolutions. ... that stricter quality control measures are necessary to ...
(Date:12/16/2009)... Ohio, Dec. 16 HDT Engineered Technologies ... generation technologies and a principal subcontractor for the ... led development of new anthropromorphic arm technology that ... prosthetic arm and hand, including a sense of ... Advanced Research Projects Agency (DARPA) Revolutionizing Prosthetics 2009 ...
(Date:12/16/2009)... 16 Ethicon, Inc., a Johnson & ... a worldwide leader in surgical care, and Acclarent, ... to designing, developing and commercializing devices that address ... today announced a definitive merger agreement whereby Ethicon ... approximately $785 million net of estimated cash on ...
Breaking Medicine Technology:MedSolutions Applauds Renewed Focus on the Dangers of Radiation Exposure 2MedSolutions Applauds Renewed Focus on the Dangers of Radiation Exposure 3HDT Develops Robotic Arm Technology for DARPA's Revolutionizing Prosthetics 2009 Program 2Ethicon Announces Definitive Agreement to Acquire Acclarent 2Ethicon Announces Definitive Agreement to Acquire Acclarent 3Ethicon Announces Definitive Agreement to Acquire Acclarent 4Prairie Heart Institute of Illinois Wins Two CLIO Healthcare Awards 15025 1Prairie Heart Institute of Illinois Wins Two CLIO Healthcare Awards 15025 2Neogen Acquires Gen Probes BioKits Food Safety Business 6639 1Neogen Acquires Gen Probes BioKits Food Safety Business 6639 2BioInformatics LLC New Report The Market Outlook for Research Products in FY2010 6637 1BioInformatics LLC New Report The Market Outlook for Research Products in FY2010 6637 2BioInformatics LLC New Report The Market Outlook for Research Products in FY2010 6637 3
... Mass., Aug. 14 StatSure,Diagnostic Systems, Inc. (OTC Bulletin ... patented, "barrel- test" format for the detection of,antibodies to ... completed,the trials needed for a CLIA waiver application and ... Food & Drug Administration (FDA) for,their review. The Company ...
... Efficacy of LBH589 in ... Myeloma, NORWALK, Conn., Aug. 14 The Multiple ... Phase II,study to determine the efficacy of LBH589 for ... LBH589 is an orally,administered deacetylase inhibitor developed by Novartis ...
Other Medicine Technology:CLIA Waiver Submitted for Rapid HIV Test Employs StatSure's 'Barrel' Technology 2CLIA Waiver Submitted for Rapid HIV Test Employs StatSure's 'Barrel' Technology 3Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor 2Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor 3
(Date:12/16/2009)... widely used human embryonic stem cell lines lack genetic ... must be addressed to ensure that all sectors of ... University of Michigan research team. ,, In the first ... 47 embryonic stem cell lines, including most of the ... determined the genetic ancestry of each line and found ...
(Date:12/16/2009)... Dec. 16 HealthSciences Institute will ... care professionals, teams and organizations who serve ... chronic diseases in employer, health plan, medical ... collaborative will offer free, noncommercial webinars on ... disease prevention, management and care improvement. Each ...
(Date:12/16/2009)... Scientists pinpoint seven that increase susceptibility to disease ... genes associated with increased susceptibility to leprosy have ... , The researchers, who analyzed more than 10,000 ... in China, said their discovery highlights the important ... the development of leprosy. , "Though leprosy is ...
(Date:12/16/2009)... Research teams led by the Wellcome Trust Sanger Institute ... , All cancers are caused by mutations in the ... person,s lifetime. The studies, of a malignant melanoma and ... all the mutations in the genomes of two cancers. ... each year: almost all are associated with smoking. The ...
(Date:12/16/2009)... Florida researchers at work on a malaria elimination study ... spread of the disease using cell phone records. , ... determine how often residents of Zanzibar travel and where ... off the coast of Tanzania in East Africa, Zanzibar ... commissioned the study as part of deliberations on whether ...
Breaking Medicine News(10 mins):Health News:U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines 2Health News:U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines 3Health News:U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines 4Health News:U-M Study Reveals Surprising Lack of Genetic Diversity in the Most Widely Used Human Embryonic Stem Cell Lines 5Health News:New Learning Collaborative to Prepare Clinicians for Better Chronic Care 2Health News:New Learning Collaborative to Prepare Clinicians for Better Chronic Care 3Health News:Leprosy Genes Identified 2Health News:Lung cancer and melanoma laid bare 2Health News:Lung cancer and melanoma laid bare 3Health News:Lung cancer and melanoma laid bare 4Health News:Lung cancer and melanoma laid bare 5Health News:Lung cancer and melanoma laid bare 6Health News:Scientists use cell phone records to predict spread of malaria 2Health News:Scientists use cell phone records to predict spread of malaria 3
... Physical therapy is a cost-effective form of ... Oct. 31 Patients with,diabetes who participate ... resistance exercise demonstrate improvements in glucose control,physical ... a study,published in the November 2008 issue ...
... dedicated to providing information and support for patients, families, and ... spinal cord injury, traumatic brain injury, and amputation. , ... ... 2008 -- Catstrophicinjury.com is a new premier one-stop ...
... Aurora Visiting Nurse,Association honored donors, caregivers and friends ... home health and hospice agency,s annual,meeting., (Photo: ... was recognized as corporate friend of,the year for ... "The relationship between Aurora VNA and Children,s Hospital ...
... coumarin, which is related to ingredient in blood thinners ... "vanilla" is often made with a toxic substance called ... Food and Drug Administration warned this week. , ... some blood thinners. Eating foods with coumarin may be ...
... Oct. 31 Blue Cross Blue Shield of Michigan ... bomb threat,received this morning., The closings affect Blue ... and Bricktown Customer Service Center,buildings. The company,s office building ... employees who work in the impacted facilities are,being sent ...
... WASHINGTON, Oct. 31 The National Coalition,for ... the McCain-Palin,campaign for ridiculing the legal rights ... campaign representative Senator Kit Bond,(R-MO), joining Vice ... in Rush,Limbaugh,s hometown of Cape Girardeau, mocking ...
Other Medicine News:Health News:New Research Shows That Combining Aerobic Exercise With High-Force Eccentric Resistance Training Improves Glucose Control in Diabetes Patients 2Health News:New Research Shows That Combining Aerobic Exercise With High-Force Eccentric Resistance Training Improves Glucose Control in Diabetes Patients 3Health News:New Online Support Site Offers Hope, Information, and Help for Patients Who Have Suffered a Catastrophic Injury 2Health News:Aurora Visiting Nurse Association of Wisconsin Honors Supporters, Volunteers 2Health News:Disability Rights Organizations Express Outrage Over Attacks at McCain-Palin Rally 2
... A new cast boot specially lasted ... a double rocker sole for easy ... around a narrow last so it ... cast boots, and with our stretchable ...
The Multi-Purpose Medical-Surgical Shoe...
The Low Profile boot provides a durable canvas upper, with an open toe and heel. Padded EVA insole protection. The lower outsole compensates for casting thickness. Available in six unisex sizes....
... enzyme-linked immunosorbent assay for the ... IgA-class antibodies to Gliadin in ... is intended to be used ... diagnosis of gastrointestinal disorders, manily ...
Medicine Products: