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Actelion Announces Positive Study with Bosentan (Tracleer) in,CTEPH

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References 1. Nick H & Kim S. Assessment of Operability in Chronic Thromboembolic Pulmonary Hypertension. Proc AmThorac Soc 2006; 3: 584-588 2. Dartevelle P et al. Chronic thromboembolic pulmonary hypertension. Eur Respir J 2004; 23:637-648. 3. LJ Rubin et al. Bosentan therapy for pulmonary arterial hypertension. N Engl J Med. 2002; 346: 896-903 4. Tracleer® SPC Actelion Ltd Actelion Ltd. is a biopharmaceutical company with its corporate headquarters in Allschwil/Basel, Switzerland. Actelion's first drug Tracleer®, an orally available dual endothelin receptor antagonist, has been approved as a therapy for pulmonary arterial hypertension. Actelion markets Tracleer® through its own subsidiaries in key markets worldwide, including the United States (based in South San Francisco), the European Union, Japan, Canada, Australia and Switzerland. At the end of September 2006, Tracleer® was commercially available in 35 countries worldwide. Actelion, founded in late 1997, is a leading player in innovative science related to the endothelium - the single layer of cells separating every blood vessel from the blood stream. Actelion's over 1,200 employees focus on the discovery, development and marketing of innovative drugs for significant unmet medical needs. Actelion shares are traded on the SWX Swiss Exchange (ticker symbol: ATLN). For further information please contact: Actelion Ltd, Gewerbestrasse 16, CH-4123 Allschwil Investor Contact Roland Haefeli +41 61 565 64 58 +1 650 624 6936 Media Contact Peter Engel +41 61 565 66 28 +1 650 624 6996 http://www.actelion.com Conference Call Actelion will host an Investor Conference Call and discussion/Q&A on Monday, 5 March 2007, 07.45 CET / 01.45 AM EST / 06.45 GMT Dial: +41 (0)91 610 56 00 (Europe) +1 (1) 866 291 4166 (U.S.
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