Navigation Links
Access and Somanta Announce Data to be Presented on Angiolix at,ASCO Oncology Conference

Pre-clinical Data Suggests Angiolix Can Inhibit Breast Cancer Growth By 75%

DALLAS and IRVINE, Calif., June 04, 2007 /PRNewswire-FirstCall/ -- Access Pharmaceuticals, Inc. (Bulletin Board: ACCP) and Somanta Pharmaceuticals, Inc. (Bulletin Board: SMPM) announced today that a scientific abstract outlining new preclinical efficacy data for Somanta's Angiolix has been selected for publication in the Proceedings of the 43rd American Society of Clinical Oncology (ASCO) Annual Meeting to be held in Chicago, IL, June 1-5, 2007. The data, in a study conducted using mouse models, shows that Angiolix has been able to achieve more than 75% growth inhibition of human breast cancer growing as xenografts in mouse.

ASCO's annual meeting is the world's premier oncology conference providing information on the latest developments in cancer treatment. As previously announced Access and Somanta have signed a definitive merger agreement for Access to acquire Somanta as a step in the creation of a combined company with a broad cancer-focused portfolio in which Angiolix will be a major program.

Angiolix is a humanized monoclonal antibody that recognizes a migrating adhesion molecule called Lactadherin. Somanta's recent data suggests that tumor cells express Lactadherin which is a factor in the growth of tumor vasculature. Several existing or potential anti-cancer drugs (such as Avastin) seek to block tumor vascularization by blocking a signaling protein know as vascular endothelial growth factor (VEGF). The binding of Angiolix to Lactadherin is thought to cause a VEGF-independent integrin receptor signaling cascade that blocks vascular endothelial cell proliferation. Due to its ability to neutralize Lactadherin-integrin receptor binding, Angiolix may be able to specifically target breast cancer cells and thereby cause tumor suppression by blocking the growth of tumor vasculature.

Dr. Agamemnon Epenetos, CEO of Som
'"/>




Page: 1 2 3

Related medicine technology :

1. PromegaExpress Expands Easy Access to Products with New Cabinet
2. Access Pharmaceuticals Announces Poster Presentations on ProLindac at the American Association for Cancer Research 2007 Annual Meeting
3. Somanta Announces the Presentation of Alchemix Data at The American Association for Cancer Research Annual Meeting
4. Cell Therapeutics, Inc. Management to Discuss Todays Announcement of Interim Pixantrone Study Results
5. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
6. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
7. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
8. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
9. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
10. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
11. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
Post Your Comments:
(Date:4/24/2015)... Introduction of new ... tools for radiosurgery/SBRT   The "Elements" ... enhancing the workflow for difficult to treat indications ... - comes full circle with the introduction of ... Elements enable on-the-fly generation of consistent treatment plans ...
(Date:4/24/2015)... Hi-Tech Pharmaceuticals refutes the results from ... of reliable scientific principles and methods and therefore ... of adulteration. The FDA is resting its very, ... misguided hope, that Methylphenylethylamine is not found in ... multiple other studies and cannot be relied on ...
(Date:4/24/2015)... , April 24, 2015 Hospira, ... in the development of biosimilar therapies, spoke about the ... at the European Generics Association (EGA) annual European Biosimilars ... The company also announced the publication of a ... to achieving the full promise of biosimilars." ...
Breaking Medicine Technology:Brainlab Introduces New Generation of VMAT* for Brain and Spine at 3rd ESTRO in Barcelona 2Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 2Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 3Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 4Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 5Hi-Tech Responds to "Bullying Tactics" Issued by FDA on Acacia Rigidula 6Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 2Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 3Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 4Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 5Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 6Hospira Leadership Presents at Preeminent European Biosimilars Forum, Announces New White Paper on Extrapolation 7
(Date:4/24/2015)... 24, 2015 As the nation recognizes ... unique sacrifices of these young men and women, the ... Veterans and their Families” presents a special training session ... to gain a better understanding of the effect of ... For those – civilian and military – who provide ...
(Date:4/24/2015)... TX (PRWEB) April 24, 2015 The Fastest ... Long, after their great success of the Xtreme Fat Loss ... industry. The fat loss blueprint that claims to help ... the attention of HealthyandFitZone.com's Stan Stevenson, prompting an investigative review. ... shows that the creators spent years researching and experimenting with ...
(Date:4/24/2015)... On February 21st, 2015, Per Wickstrom had ... ItsNotAboutMe.TV contributor Karen Salkin at Durkin Entertainment’s EcoLuxe Lounge, ... addiction, of which Wickstrom is the founder. Making appearances ... the EcoLuxe Lounge is a gathering of some of ... products and services. Among the many roles that she ...
(Date:4/24/2015)... Carinsurancequotesinfo.com has released a new blog ... to qualify for auto insurance as a ... auto insurance online, without having to follow a special ... parents can reduce their auto insurance expenses. The tips ... explained. , Clients can now visit an insurance ...
(Date:4/24/2015)... 2015 Olive Fertility Centre is proud ... and co-director, has been honoured for his pioneering work ... of Hope Gala. , “We are very pleased ... who has been at the forefront of fertility research ... Séguin, Executive Director of Fertile Futures--a Canadian non-profit organization ...
Breaking Medicine News(10 mins):Health News:Coalition Presents Resiliency Training to Raise Awareness during Month of the Military Child (#MOTMC2015) 2Health News:Fastest Fat Loss Week Ever Review Revealed on Healthy & Fit Zone 2Health News:Karen Salkin Talks with Per Wickstrom at the 2015 EcoLuxe Lounge and the "Salute to the Oscars" Celebration 2Health News:Auto Insurance Discounts for Single Parents - How to Qualify for Low Rates 2Health News:Olive Fertility Centre Co-founder, Dr Al Yuzpe, Recognized as a Pioneer in Fertility Preservation 2
... the aftereffects of a chlorine gas disaster in a South ... to expect and how to prepare emergency response systems for ... The study is now available in the January 2009 issue ... , "This is one of the largest community exposures to ...
... symptoms are highly prevalent in different geographic populations ... the lives of those affected. Examples include GERD, ... These problems have an impact on the individual,s ... community-based research evaluating the impact of chronic gastrointestinal ...
... Multi-Serve Canisters Make it Easy to Mix with Water ... 2009 quickly approaches, Americans will begin making New Year,s ... According to this year,s survey from FranklinCovey Products ... licensee of consumer products for FranklinCovey Co, , ...
... Fisher Vista, LLC has reported,its seventh consecutive year of ... core product HRmarketer.com and strong demand for media,relations and ... The HRmarketer Services Group, established ... Services Group provides HR vendors with a,one-stop source for ...
... ARAY ), a global leader in the ... scheduled to present at the 11th Annual Needham Growth ... 2009 at 11:00 a.m. EST (8:00 a.m. PST).A live ... the investor relations page of the Company,s Web site ...
... Walks Drive Home Importance of Awareness and Education of ... effort to raise money for The Kidney TRUST(TM) -- ... chronic kidney disease (CKD) -- DaVita Inc., the nation,s ... the 3rd annual "Kidney Awareness Time(TM)" Walk-a-thon (The KAT ...
Cached Medicine News:Health News:New study examines effects of Graniteville, S.C., chlorine gas disaster 2Health News:New study examines effects of Graniteville, S.C., chlorine gas disaster 3Health News:Chronic gastrointestinal symptoms in Korean population 2Health News:Ocean Spray(R) Announces Sugar-Free Drink Mixes - A Sweet Way for Dieters to 'Stick' to Their Resolutions 2Health News:Fisher Vista, LLC Reports Seventh Consecutive Year of Revenue Growth and Profitability 2Health News:Accuray Incorporated to Present at 11th Annual Needham Growth Stock Conference 2Health News:Thousands of DaVita Teammates Raise Over $100,000 for CKD Programs 2Health News:Thousands of DaVita Teammates Raise Over $100,000 for CKD Programs 3