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Access Pharmaceuticals Announces Poster Presentations on ProLindac,at the American Association for Cancer Research 2007 Annual Meeting

DALLAS, April 16, 2007 /PRNewswire-FirstCall/ -- ACCESS PHARMACEUTICALS, INC. announced today that results of studies of the mechanism of ProLindac's anticancer activity will be presented today at the American Association for Cancer Research (AACR) 2007 annual meeting in Los Angeles at the Los Angeles Convention Center. The two poster presentations describe preclinical studies performed by Access collaborators at two prominent institutes in France.

"We are delighted to have two ProLindac poster presentations at one of the most prestigious scientific conferences in cancer," stated David P. Nowotnik, Access' Senior Vice President, Research and Development. "The presentations reaffirm ProLindac's potential to become a leading cancer treatment. The posters focus on how ProLindac can be delivered in much higher doses than current therapies and shows its potential for superior efficacy, given alone as well as in combination with other anticancer compounds. Access has successfully completed a Phase 1 clinical study indicating at least five times more platinum could be administered to patients with ProLindac than oxaliplatin before the onset of toxicity. We are currently studying ProLindac in a Phase 2 monotherapy trial, treating patients with relapsed ovarian cancer."

The first poster is entitled "Antiproliferative effects of ProLindac, a novel DACH-platinum linked polymer-compound, compared to oxaliplatin and cisplatin in a panel of human cancer cell lines." This poster describes studies which examine ProLindac's cytotoxic effects either as single agent or in combination with other cytotoxics, and molecular mechanisms of action of ProLindac in comparison to oxaliplatin and cisplatin in a panel of human cancer cell lines. Results of the study indicated ProLindac and oxaliplatin showed similar cytotoxicity profiles when used in combination with either Gemcitabine, Docetaxel, 5-FU or SN38 (a camptothecin a
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