Navigation Links
Accentia Biopharmaceuticals Announces Favorable Interim Blinded,Data on SinuNase in Its Fast-Tracked Pivotal Phase 3 Clinical Trial,for Chronic Sinusitis

TAMPA, Fla.--(BUSINESS WIRE)--Jun 28, 2007 - Accentia Biopharmaceuticals, Inc. (NASDAQ: ABPI) announced on Wednesday, June 27 at the Jefferies Healthcare Conference that its interim analysis of the blinded data on the first fifty patients in the Fast-Tracked Phase 3 clinical study of SinuNase(TM), at 8 weeks post-randomization, has demonstrated substantial improvement in resolution of one or both of the cardinal symptoms of chronic sinusitis, and substantial improvement in intranasal polyposis. Resolution of both cardinal symptoms at the end of 16 weeks is the primary endpoint of the ongoing Phase 3 study. Based on this interim blinded data, approximately 42% of patients randomized reported resolution of one or both cardinal symptoms. In addition, approximately 47% of patients were evaluated as having improved endoscopy scores. It should be noted, prior to randomization, potential trial participants were required to irrigate with saline twice daily for two weeks and only those who showed no placebo effect were randomized. The randomization between SinuNase and placebo control is 1:1, meaning that 50% of the patients in the blinded interim analysis should be on SinuNase, and 50% on placebo control.

"The data reported is very encouraging," said Dr. Frank E. O'Donnell Jr., Chairman and Chief Executive Officer of Accentia Biopharmaceuticals. "While we cannot determine which patients are receiving SinuNase and which are receiving placebo control until the study is completed and unblinded, the fact that there are resolution of symptoms and improvement in endoscopy in a substantial percentage of patients suggests to me that we are on track to reach our anticipated outcome for SinuNase in the Phase 3 study. It seems unlikely to me that patients receiving placebo would have a substantial improvement in polyps. In fact, in patients who experienced no resolution of symptoms, the endoscopy scores improved by just 2%. In pa
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Accentia Biopharmaceuticals Scientific Presentations Demonstrate Increasing Acceptance of Fungal Etiology of Chronic Sinusitis at the Annual Meeting of the American Academy of Allergy, Asthma, and Immunology
2. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
3. Keryx Biopharmaceuticals, Inc. Announces Positive Phase I and Phase II Data on KRX-0401 in Patients with Relapsed/Refractory Multiple Myeloma and Waldenstroms Macroglobulinemia
4. Keryx Biopharmaceuticals, Inc. Announces Poster Presentations Highlighting Mechanism of Action and Clinical Activity of Sulonex(TM) (sulodexide oral gelcap) at the Upcoming American Diabetes Association 67th Scientific Sessions in Chicago, Illinois
5. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
6. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
7. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
8. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
9. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
10. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
11. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
Post Your Comments:
(Date:4/1/2015)... Salix Pharmaceuticals, Ltd. (the " Company " ... Valeant Pharmaceuticals International, Inc. (NYSE: VRX ) (TSX:VRX), ... Fundamental Changes, Make-Whole Fundamental Changes and Merger Event, Fundamental ... and Offer to Purchase (the " Notice ") to ... (the " Notes "), pursuant to the Indenture, dated ...
(Date:4/1/2015)... , April 1, 2015  Hologic, Inc. (NASDAQ: ... holders of the 2.00% Convertible Exchange Senior Notes due ... and Wilmington Trust Company, the trustee, paying agent and ... to convert the notes.  This conversion right is subject ... notes dated as of December 10, 2007, as supplemented ...
(Date:4/1/2015)... ATLANTA , April 1, 2015  The ... medication, and dietary supplements to treat attention-deficit/hyperactivity disorder ... than one half of children with ADHD were ... Centers for Disease Control and Prevention (CDC) study, ... Health Care Needs," published today in The ...
Breaking Medicine Technology:Salix Provides Notice of Fundamental Changes, Make-Whole Fundamental Changes and Merger Event Relating to Its 1.5% Convertible Senior Notes Due 2019 2Salix Provides Notice of Fundamental Changes, Make-Whole Fundamental Changes and Merger Event Relating to Its 1.5% Convertible Senior Notes Due 2019 3Salix Provides Notice of Fundamental Changes, Make-Whole Fundamental Changes and Merger Event Relating to Its 1.5% Convertible Senior Notes Due 2019 4Salix Provides Notice of Fundamental Changes, Make-Whole Fundamental Changes and Merger Event Relating to Its 1.5% Convertible Senior Notes Due 2019 5Salix Provides Notice of Fundamental Changes, Make-Whole Fundamental Changes and Merger Event Relating to Its 1.5% Convertible Senior Notes Due 2019 6Salix Provides Notice of Fundamental Changes, Make-Whole Fundamental Changes and Merger Event Relating to Its 1.5% Convertible Senior Notes Due 2019 7Hologic Delivers Notice that Holders of 2.00% Convertible Exchange Senior Notes Due 2037 are Eligible to Convert 2CDC publishes first national study on use of behavioral therapy, medication and dietary supplements for ADHD in children 2CDC publishes first national study on use of behavioral therapy, medication and dietary supplements for ADHD in children 3CDC publishes first national study on use of behavioral therapy, medication and dietary supplements for ADHD in children 4
... IRIDEX Corporation (Nasdaq: IRIX ) today announced ... the ROTH 23rd Annual OC Growth Stock Conference on Monday, ... being held March 13-16 at the Ritz Carlton Laguna Niguel ... accessible by live webcast on the Investor section of IRIDEX,s ...
... 2011 To help reduce state Medicaid spending, the ... in charge of the state,s Medicaid program, has proposed ... like those in the private sector that are more ... would save state taxpayers $82 million.  Governors Chris Christie ...
Cached Medicine Technology:Texas Health and Human Services Commission: Modernize Medicaid Pharmacy to Save State $82 Million 2
(Date:4/2/2015)... (PRWEB) April 02, 2015 Steviva ... and custom sweetening solutions, recently announced the rebranding ... are Erysweet+ with stevia and Erysweet+ 100 mesh ... Stevia Blend fine powder, respectively. , Erysweet+ with ... and naturally fermented erythritol. It delivers a natural ...
(Date:4/2/2015)... 02, 2015 New York Dynamic Neuromuscular ... first time in New York City, a groundbreaking, conservative ... a stroke (or other types of neurological diseases that ... , A stroke is considered a cerebrovascular accident (CVA) ... brain tissue resulting in damage to the nerve cells. ...
(Date:4/1/2015)... PA (PRWEB) April 01, 2015 Glen ... with Illinois-based Pearl Valley Farm’s, Healthy Grow fertilizer line ... with Healthy Grow. , Holganix manufactures a line of ... key ingredients to promote optimal plant, turf and tree ... only self-sustaining egg farms, and a manufacturer of organic ...
(Date:4/1/2015)... Levi's® Stadium , located in Santa Clara ... The San Francisco 49ers from the National Football League call ... Levi’s Stadium has been the home of countless memorable events. ... thus far include a game from the 2015 National Hockey ... Jose Sharks, Wrestlemania 31 and an International Friendly Soccer Match ...
(Date:4/1/2015)... April 01, 2015 One year ago today, ... Family Care Center in the United States and changed the ... 16,000 square feet facility has served more than 100,000 troops ... these visitors were wounded, ill and injured and their families, ... nation’s largest military medical centers in the country. After opening ...
Breaking Medicine News(10 mins):Health News:Steviva Ingredients Announces Erysweet+ Rebrand 2Health News:Virtual Environment Treatment Available for the First Time in NYC for Patients with Stroke 2Health News:Holganix Expands Its Organic Turf Portfolio Success by Partnering with Pearl Valley Farms to Produce an Organic-Based Granular Fertilizer 2Health News:Levi's® Stadium Tickets for Super Bowl 50, Kenny Chesney & Jason Aldean, One Direction, Taylor Swift and Luke Bryan Available at Discounted Prices at TicketDown.com 2Health News:Levi's® Stadium Tickets for Super Bowl 50, Kenny Chesney & Jason Aldean, One Direction, Taylor Swift and Luke Bryan Available at Discounted Prices at TicketDown.com 3Health News:USO’s Warrior and Family Center at Bethesda Marks First Anniversary and More than 100,000 Servicemen and Women Served 2Health News:USO’s Warrior and Family Center at Bethesda Marks First Anniversary and More than 100,000 Servicemen and Women Served 3Health News:USO’s Warrior and Family Center at Bethesda Marks First Anniversary and More than 100,000 Servicemen and Women Served 4Health News:USO’s Warrior and Family Center at Bethesda Marks First Anniversary and More than 100,000 Servicemen and Women Served 5
... CHENNAI, India, July 31 Oscar Award Winner, Dr.,A.R. ... Quaternary Care Paediatric Hospital in the Apollo Hospitals,Group. , ... The Apollo Children,s Hospital is designed to ... age of 16 years all,under one roof. Established on a ...
... , ... and Sam Brownback, and U.S. Representatives Lynn Jenkins, Dennis Moore, Jerry Moran and Todd Tiahrt ... Homeland Security,s (DHS) analysis of whether Foot and Mouth Disease (FMD) research can be conducted ... ...
... ... first applications can benefit from choosing representation early in the process. , ... Belleville, IL (Vocus) July 31, ... (SSDI) benefits this year and experiencing difficulties, according to Allsup , a nationwide ...
... ... unexpected surprise last week after using a glyph that was designed by Holy ... in HGFs manual that has just been released entitled "Unlocking the Power of ... been empowered by the highest Source to assist people in clearing issues that ...
... ... time with patients and speeds clinical and admissions processes by eliminating the constraints of ... ... Hospital in Greeneville, Tennessee, selected an electronic forms management system in 2004, they ...
... ... role in the recognition and management of snoring and sleep apnea, announced today that it ... row. , ... (PRWEB) July 31, 2009 -- Snoring Isn,t Sexy, LLC, a company dedicated to disseminating information ...
Cached Medicine News:Health News:Oscar Award Winner, Dr. A.R. Rahman inaugurates Apollo Children's Hospital - the First Standalone Quaternary Care Paediatric Hospital in the Apollo Hospitals Group 2Health News:Kansas Delegation: GAO Report Short on Expertise, Long on Errors; NBAF Critical to Protect Nation's Food Supply 2Health News:Allsup Answers Common Questions People Have About Social Security Disability 2Health News:Allsup Answers Common Questions People Have About Social Security Disability 3Health News:Allsup Answers Common Questions People Have About Social Security Disability 4Health News:Allsup Answers Common Questions People Have About Social Security Disability 5Health News:Holy Ground Farm, Inc Announces Impotency Resolved by Simple Non-Invasive Method 2Health News:Holy Ground Farm, Inc Announces Impotency Resolved by Simple Non-Invasive Method 3Health News:Electronic Forms Management Suite from Access Delivers Admissions Efficiency at Laughlin Memorial Hospital 2Health News:Electronic Forms Management Suite from Access Delivers Admissions Efficiency at Laughlin Memorial Hospital 3Health News:SnoringIsntSexy.com Tops 21,000 Site Visits for Second Month in a Row 2
... kit features a patented Per-fit™ flexible PVC ... a low-profile cuff specifically designed to reduce ... the patients anatomy. The kit s unique ... tube snugly, allowing for an easier transition ...
... Self-contained kits provide convenience and cost control. ... care trays offer a variety of wound ... management of the tracheostomized patient. , ... and trays with disposable inner cannula for ...
Disposable tracheostomy care tray....
... Medline Has the Right Solution For ... tracheostomy clean and care tray features the ... of this important infection control task. Designed ... the individual needs of each patient and ...
Medicine Products: