Navigation Links
Accentia Biopharmaceuticals Announces Favorable Interim Blinded,Data on SinuNase in Its Fast-Tracked Pivotal Phase 3 Clinical Trial,for Chronic Sinusitis

TAMPA, Fla.--(BUSINESS WIRE)--Jun 28, 2007 - Accentia Biopharmaceuticals, Inc. (NASDAQ: ABPI) announced on Wednesday, June 27 at the Jefferies Healthcare Conference that its interim analysis of the blinded data on the first fifty patients in the Fast-Tracked Phase 3 clinical study of SinuNase(TM), at 8 weeks post-randomization, has demonstrated substantial improvement in resolution of one or both of the cardinal symptoms of chronic sinusitis, and substantial improvement in intranasal polyposis. Resolution of both cardinal symptoms at the end of 16 weeks is the primary endpoint of the ongoing Phase 3 study. Based on this interim blinded data, approximately 42% of patients randomized reported resolution of one or both cardinal symptoms. In addition, approximately 47% of patients were evaluated as having improved endoscopy scores. It should be noted, prior to randomization, potential trial participants were required to irrigate with saline twice daily for two weeks and only those who showed no placebo effect were randomized. The randomization between SinuNase and placebo control is 1:1, meaning that 50% of the patients in the blinded interim analysis should be on SinuNase, and 50% on placebo control.

"The data reported is very encouraging," said Dr. Frank E. O'Donnell Jr., Chairman and Chief Executive Officer of Accentia Biopharmaceuticals. "While we cannot determine which patients are receiving SinuNase and which are receiving placebo control until the study is completed and unblinded, the fact that there are resolution of symptoms and improvement in endoscopy in a substantial percentage of patients suggests to me that we are on track to reach our anticipated outcome for SinuNase in the Phase 3 study. It seems unlikely to me that patients receiving placebo would have a substantial improvement in polyps. In fact, in patients who experienced no resolution of symptoms, the endoscopy scores improved by just 2%. In pa
'"/>




Page: 1 2 3 4

Related medicine technology :

1. Accentia Biopharmaceuticals Scientific Presentations Demonstrate Increasing Acceptance of Fungal Etiology of Chronic Sinusitis at the Annual Meeting of the American Academy of Allergy, Asthma, and Immunology
2. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
3. Keryx Biopharmaceuticals, Inc. Announces Positive Phase I and Phase II Data on KRX-0401 in Patients with Relapsed/Refractory Multiple Myeloma and Waldenstroms Macroglobulinemia
4. Keryx Biopharmaceuticals, Inc. Announces Poster Presentations Highlighting Mechanism of Action and Clinical Activity of Sulonex(TM) (sulodexide oral gelcap) at the Upcoming American Diabetes Association 67th Scientific Sessions in Chicago, Illinois
5. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
6. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
7. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
8. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
9. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
10. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
11. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
Post Your Comments:
(Date:7/31/2015)...  Semler Scientific, Inc. (Nasdaq: SMLR ), a ... insurers and physician groups, today reported financial results for ... "In the second quarter of 2015, Semler reported ... 54%, quarter over quarter revenue growth of 8%, and ... FloChec® units of 18%," said Doug Murphy-Chutorian, M.D., chief ...
(Date:7/31/2015)... 2015  Xencor, Inc. (NASDAQ: XNCR ), a ... treatment of autoimmune diseases, asthma and allergic diseases, and ... Hata to its board of directors. ... development is a tremendous asset to our board," said ... officer of Xencor. "Xencor faces a range of opportunities ...
(Date:7/31/2015)... , July 31, 2015 ... solutions for video, data and cloud computing operators ... a leading pharma giant for Internet of Things ... IoT applications offered on subscription model. ... Pharma giant is striving for business innovations to ...
Breaking Medicine Technology:Semler Reports Second Quarter 2015 Financial Results 2Semler Reports Second Quarter 2015 Financial Results 3Semler Reports Second Quarter 2015 Financial Results 4Semler Reports Second Quarter 2015 Financial Results 5Semler Reports Second Quarter 2015 Financial Results 6Xencor Appoints Yujiro S. Hata to Board of Directors 2Xencor Appoints Yujiro S. Hata to Board of Directors 3Magnaquest Signs a POC With a Leading Pharma Giant in Europe to Manage Subscription Management and Billing for Internet of Things (IoT) 2
... the community pharmacy chain, has revealed that one in four* (24%) ... - has taken or applied medicines which they later discovered were ... half (53%) of people do not always check the expiry date ... member. This is worrying considering that nearly one ...
... 4, 2011 Sanofi-aventis (EURONEXT: SAN and NYSE: ... exchange offer for all outstanding shares of common stock of ... and withdrawal rights expired at 11:59 p.m., New York City ... offer has advised sanofi-aventis that, as of the expiration time, ...
Cached Medicine Technology:Lloydspharmacy Reveals Over 11 Million Britons Risking Health by Taking Old Medicines 2Lloydspharmacy Reveals Over 11 Million Britons Risking Health by Taking Old Medicines 3Sanofi-aventis Successfully Completes Exchange Offer for Genzyme Corporation 2Sanofi-aventis Successfully Completes Exchange Offer for Genzyme Corporation 3Sanofi-aventis Successfully Completes Exchange Offer for Genzyme Corporation 4Sanofi-aventis Successfully Completes Exchange Offer for Genzyme Corporation 5Sanofi-aventis Successfully Completes Exchange Offer for Genzyme Corporation 6
(Date:7/31/2015)... , ... July 31, 2015 , ... ... industry players to know in predictive health analytics , Jvion continues to ... The firm creates predictive software that targets patient and population level illness to ...
(Date:7/31/2015)... Jacksonville, FL (PRWEB) , ... July 31, 2015 ... ... has announced an important workshop at its new True North Conference Center. The ... attend so that the Jacksonville community may be more aligned in the effort ...
(Date:7/31/2015)... ... ... the article published July 27 on My News LA, a fire that broke ... city’s fire department before it caused major damage throughout the building. The article also notes ... was a fire alarm system that tipped off fire fighters so they could arrive at ...
(Date:7/31/2015)... ... July 31, 2015 , ... As part of their company mission, Dallas ... animal welfare organizations is essential to the longevity of their business. It is ... Association of Professional Pet Sitters (NAPPS) annual Presents 4 Pets supply drive. ...
(Date:7/31/2015)... ... , ... Girl Scouts of Historic Georgia and Peach State Health Plan are ... a Friend First" program. Representatives from Peach State Health Plan presented a $10,000 check ... and our parent company, Centene Corporation, are dedicated to raising anti-bullying awareness. We are ...
Breaking Medicine News(10 mins):Health News:Jvion Showcased as Leader in the Predictive Analytic Market 2Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 2Health News:Lakeview Health Links Sex Trafficking and Addiction in Special Jacksonville Educational Workshop 3Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 2Health News:Article on Recent Pasadena Courtroom Fire Highlights the Effectiveness of Fire Alarm Systems, Says Fire Protection Group Inc 3Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 2Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 3Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 4Health News:Peach State Health Plan Presents $10,000 Check for “Be a Friend First” Anti-Bullying Program to Local Girl Scouts 2
... Robson is ready to fight against cancer for the fifth time ... diagnosed with cancer for the fifth time, started a six-week bout ... lungs. ,He has battled cancer on and off for ... ,"Of course, it's not the greatest news I've ever had ...
... rate in the United States appears to be strongly ... according to study. ,Dr. Winchester and ... and nitrates measurements in surface water were highest (April-July) ... (Aug.-Sept.). ,More than 27 million U.S. ...
... routine trauma abdomen and pelvis CT compared to plain radiographs, ... the University of Cincinnati. ,The study consisted of ... CT within three days of an injury. These patients were ... lumbar spine fracture. ,According to the study, ...
... popular city rankings of the fattest cities, the fittest ... cities . Now, in the first-of-its-kind survey, the American ... sun protection seriously and those that fail to make ... ,The "RAYS: Your Grade" survey polled adults in 32 ...
... positive man hailing from a Bihar village, who was socially ostracized, ... man, whose name is not known, was the only bread earner ... district, about 150 km from here. The immediate provocation for the ... numbered. ,"He poured kerosene oil and set himself ablaze. ...
... accolades for promoting good health. The latest news about ... mouth. ,Researchers from the University of Wisconsin ... heal the infection and avoid what could otherwise lead ... doctor at the University of Wisconsin introduced this unique ...
Cached Medicine News:Health News:Bobby Robson Diagnosed With Cancer for Fifth Time 2Health News:Premature Birth Linked With Increased Use of Pesticides 2Health News:New Survey List Out Cities That Take Sun Protection Seriously 2Health News:New Survey List Out Cities That Take Sun Protection Seriously 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: