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AVEO Pharmaceuticals Novel Oncology Research Platform and Clinical,Pipeline to Be Featured at AACR

nomic Analysis of Human Cancer - Room 304 A-C

-- Wednesday, April 18, 2007 at 10:25 a.m. to 10:40 a.m. "A novel chimeric approach to modeling cancer in mice reveals that EGFR dependency in lung tumors is mediated through non canonical RTK-MAPK signaling" - Mini-symposium: Mouse Models of Cancer - Room 406 A-B

-- Wednesday, April 18, 2007 at 10:40 a.m. to 10:55 a.m. "Genetically engineered human breast cancer in mouse (HIM): A novel cancer model system that progresses in vivo and exhibits phenotypic variations" - Mini-symposium: Mouse Models of Cancer - Room 406 A-B

The schedule for poster presentations at the AACR Annual Meeting is listed below:

-- Monday, April 16, 2007 at 8:00 a.m. to 12:00 p.m. "Genetically engineered murine tumor models for drug response prediction: Population based pathway profiles predict response to repamycin in a HER2 driven breast model" - Poster Session: Mouse Models in Cancer - Section 23, Board 28

-- Monday, April 16, 2007 at 1:00 p.m. to 5:00 p.m. "Directed complementation of inducible tumor models: An approach to generate broad panels of tumors with defined genetic contexts" - Poster Session: Mouse Models of Cancer - Section 22, Board 29

-- Tuesday, April 17, 2007 at 8:00 a.m. to 12:00 p.m. "AV-412, a potent EGFR/HER2 TK inhibitor causes tumor regression in novel genetically engineered EGFRL858R and EGFRL858R and T790M lung tumor models" - Poster Session: EGFR Inhibition - Section 28, Board 6

-- Tuesday, April 17, 2007 at 8:00 a.m. to 12:00 p.m. "A novel beta-Catenin dependent p53DN mouse model of colon cancer displays stage dependent expression of EGFR" - Poster Session: Mouse Models of Cancer - Section 20, Board 9

-- Tuesday, April 17, 2007 at 8:00 a.m. to 12:00 p.m. "A chimeric mouse model of ovarian cancer driven by inducible expression of PI3K catalytic subunit (p110alpha)" - Poster Session: Mouse Models of Cancer - Section 21, Board 4

-- Tuesday, April 17, 2007 at 8:0
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