ALISO VIEJO, Calif.--(BUSINESS WIRE)--May 8, 2007 - AVANIR
Pharmaceuticals (NASDAQ:AVNR) today announced Phase III data on the
efficacy, safety and improvements in patient-centered outcomes in
patients with diabetic peripheral neuropathic (DPN) pain treated
with the investigational drug Zenvia(TM) (dextromethorphan /
quinidine) will be presented in two scientific posters at the
Second International Congress on Neuropathic Pain, being held in
Berlin, Germany on June 7 to 10, 2007.
Both posters will be presented at Poster Session 1: Clinical -
Pharmacotherapy on Friday, June 8, 2007, between 1:30 p.m. and 3:30
p.m. Central European time (CET).
"This scientific congress serves as a showcase for new
developments in pain treatment. We are pleased that these data have
been recognized as important by the congress organizers and
accepted for presentation," said Randall Kaye, MD, Chief Medical
Officer of AVANIR Pharmaceuticals.
The accepted posters are:
-- Poster number 1497: EFFICACY AND SAFETY OF
DEXTROMETHORPHAN/QUINIDINE IN TREATING PAINFUL DIABETIC PERIPHERAL
NEUROPATHY: RESULTS OF A PHASE III, DOUBLE-BLIND, RANDOMIZED,
PLACEBO-CONTROLLED TRIAL
-- Poster number 1498: IMPROVED PATIENT-CENTERED OUTCOMES WITH
DEXTROMETHORPHAN/QUINIDINE VS PLACEBO IN A PHASE III, DOUBLE-BLIND,
RANDOMIZED, PLACEBO-CONTROLLED TRIAL INVESTIGATING PAINFUL DIABETIC
PERIPHERAL NEUROPATHY
On April 18, 2007 AVANIR Pharmaceuticals announced positive
top-line results from a Phase III study of Zenvia in patients with
DPN pain. In the trial, two doses of Zenvia, 45/30 mg DMQ dosed
twice daily (DMQ 45) and 30/30 mg DMQ dosed twice daily (DMQ 30),
were compared to placebo based on daily patient diary entries for
the Pain Rating Scale, which was the primary endpoint as defined in
the Special Protocol Assessment (SPA) with the U.S. Food and Drug
Administration (FDA). Both Zenvia treatment groups had lower pain
rating
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