Navigation Links
AVANIR Pharmaceuticals Presents Zenvia Phase III Data in Diabetic,Peripheral Neuropathic Pain at International Congress on,Neuropathic Pain

s (p less than 0.0001 for both comparisons), demonstrating significantly greater reductions in pain compared with placebo. Pain score averaged over the study periods were significantly lower than placebo in the DM/Q 45 arm for comparisons at days 30, 60 and 90 (p less than 0.0001 for each comparison) and in the DM/Q 30 arm (p less than 0.0001 at days 30 and 60, p=0.0071 at day 90). The consistency in the magnitude of response suggests that the pain reduction obtained with active treatment relative to placebo were maintained over the entire study duration.

-- Improvements from baseline with active treatment appeared to be dose dependent, with the higher dose resulting in improvements that were almost twice as great as placebo.

-- Both doses demonstrated significantly better improvements in pain from baseline that were maintained over the duration of the study.

-- The incidence of AEs was higher in the DM/Q 45 group (91%), compared with placebo (80%) and DM/Q 30 (79%), with the proportion of patients discontinuing due to an AE higher in both active treatments compared with placebo.

-- The most common AEs were dizziness, nausea, diarrhea, fatigue and somnolence and were generally mild to moderate in severity.

-- There were no statistically significant differences in serious adverse event rates reported in the DM/Q 45, DM/Q 30 and placebo groups, and no deaths occurred during the study.

Poster: "IMPROVED PATIENT-CENTERED OUTCOMES WITH DEXTROMETHORPHAN/ QUINIDINE VS PLACEBO IN A PHASE III, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL INVESTIGATING PAINFUL DIABETIC PERIPHERAL NEUROPATHY," reports on the secondary efficacy endpoints in the Phase III study on outcomes of importance to patients, including pain relief, sleep and quality-of-life. Highlights include:

-- Both Zenvia doses were significantly superior to placebo in relieving pain. The pattern reported in the Pain Relief Scale complemented that shown by the Pai
'"/>




Page: 1 2 3 4 5 6 7

Related medicine technology :

1. AVANIR Pharmaceuticals to Present Zenvia Phase III Data in Diabetic Peripheral Neuropathic Pain at Second International Congress on Neuropathic Pain
2. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
3. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
4. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
5. Auxilium Pharmaceuticals to Present at the 2007 CEUT Emerging Growth Opportunities Conference
6. Sunesis Pharmaceuticals to Present at the C. E. Unterberg, Towbin Emerging Growth Conference
7. EPIX Pharmaceuticals to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference
8. Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
9. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
10. Portola Pharmaceuticals Announces Positive Phase II EXPERT Results and Additional Oral and Poster Presentations at the XXI Congress of the International Society on Thrombosis and Haemostasis (ISTH)
11. Cyclacel Pharmaceuticals Announces Results of Phase II Seliciclib Combination Studies
Post Your Comments:
(Date:12/15/2009)... Flextronics (Nasdaq: FLEX ) today ... announced acquisition of SloMedical S.R.O., a leading ... from tubing sets to complex devices for ... provides a broad set of capabilities to ... Terms of the deal were not disclosed. ...
(Date:12/15/2009)... healthcare providers who have already immunized patients most ... virus may now offer the vaccine to anyone ... today. ,, Pennsylvania is expanding the H1N1 ... doses of vaccine have been allocated to healthcare ... priority groups. ,, "Many certified providers have already ...
(Date:12/15/2009)... 15 Reportlinker.com announces that ... available in its catalogue: ,, ... in the U.S. and its International ... http://www.reportlinker.com/p0167745/Surgical-and-Medical-Instrument-Manufacturing-Industry-in-the-US-and-its-International-Trade-[Q4-2009-Edition].html ,, The just ... Medical Instrument Manufacturing Industry report is ...
Breaking Medicine Technology:Flextronics Completes SloMedical Acquisition 2Department of Health Urges Expanded H1N1 Vaccination Efforts to Include All Patients 2Reportlinker Adds Surgical and Medical Instrument Manufacturing Industry in the U.S. and its International Trade [Q4 2009 Edition] 2Reportlinker Adds Surgical and Medical Instrument Manufacturing Industry in the U.S. and its International Trade [Q4 2009 Edition] 3Reportlinker Adds Surgical and Medical Instrument Manufacturing Industry in the U.S. and its International Trade [Q4 2009 Edition] 4Reportlinker Adds Surgical and Medical Instrument Manufacturing Industry in the U.S. and its International Trade [Q4 2009 Edition] 5Reportlinker Adds Surgical and Medical Instrument Manufacturing Industry in the U.S. and its International Trade [Q4 2009 Edition] 6Reportlinker Adds Surgical and Medical Instrument Manufacturing Industry in the U.S. and its International Trade [Q4 2009 Edition] 7Reportlinker Adds Surgical and Medical Instrument Manufacturing Industry in the U.S. and its International Trade [Q4 2009 Edition] 8Ziehm Imaging and BrainLAB Improve Trauma and Spine Surgery With X ray Based Navigation 14594 1Ziehm Imaging and BrainLAB Improve Trauma and Spine Surgery With X ray Based Navigation 14594 2Ziehm Imaging and BrainLAB Improve Trauma and Spine Surgery With X ray Based Navigation 14594 3Ziehm Imaging and BrainLAB Improve Trauma and Spine Surgery With X ray Based Navigation 14594 4Ziehm Imaging and BrainLAB Improve Trauma and Spine Surgery With X ray Based Navigation 14594 5Sucrets 28R 29 ICE and Twentieth Century Fox Home Entertainment Challenge Kids to Keep the Environment Healthy this Cold Season 5699 1Sucrets 28R 29 ICE and Twentieth Century Fox Home Entertainment Challenge Kids to Keep the Environment Healthy this Cold Season 5699 2Sucrets 28R 29 ICE and Twentieth Century Fox Home Entertainment Challenge Kids to Keep the Environment Healthy this Cold Season 5699 3New Data Show CIMZIA 28R 29 28certolizumab pegol 29 Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients 5696 1New Data Show CIMZIA 28R 29 28certolizumab pegol 29 Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients 5696 2New Data Show CIMZIA 28R 29 28certolizumab pegol 29 Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients 5696 3New Data Show CIMZIA 28R 29 28certolizumab pegol 29 Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients 5696 4New Data Show CIMZIA 28R 29 28certolizumab pegol 29 Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients 5696 5New Data Show CIMZIA 28R 29 28certolizumab pegol 29 Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients 5696 6New Data Show CIMZIA 28R 29 28certolizumab pegol 29 Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients 5696 7New Data Show CIMZIA 28R 29 28certolizumab pegol 29 Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients 5696 8New Data Show CIMZIA 28R 29 28certolizumab pegol 29 Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients 5696 9New Data Show CIMZIA 28R 29 28certolizumab pegol 29 Provides Sustained and Significant Symptom Improvement in Moderate to Severe Crohns Patients 5696 10
(Date:12/16/2009)... American Podiatric Medical Association’s Seal of Acceptance , ... ... As shoppers continue their search for the perfect gift this ... items that are considered healthy for the environment. When it ... of today’s most stylish items are also healthy for feet—making ...
(Date:12/16/2009)... one-fourth the time it takes to obtain a bachelor degree, ... ophthalmic assistant. , ... (Vocus) December ... The National Report Card on Higher Education" by the National ... tuition have outpaced price increases in other sectors of the ...
(Date:12/16/2009)... Christmas rush Hallmark Cards have announced a great addition to ... an easy to navigate website at www.hallmark.co.uk/specialoccasions , customers can ... their own words and photos and then order as many copies ... ... Bradford, UK (PRWEB) December 16, 2009 -- Just in time ...
(Date:12/16/2009)... The holidays are rapidly approaching and what would be the perfect ... stem cells, of course! Celebrity Beauty Engineer® and Licensed Esthetician Mary ... how to look and feel their best! , ... ... what kind of gift does a person get that special woman ...
(Date:12/16/2009)... Instead of buying another product or thing for your loved ones ... them personal assistant services like housekeeping, errand running, child care, and ... ... (PRWEB) December 12, 2009 -- Residents of the Denver and Boulder ... year to their friends and loved ones by using Delegate Source,s ...
Breaking Medicine News(10 mins):Health News:Put Some "Green" Into Gift-Giving With Eco-Friendly Footwear Products 2Health News:Put Some "Green" Into Gift-Giving With Eco-Friendly Footwear Products 3Health News:Put Some "Green" Into Gift-Giving With Eco-Friendly Footwear Products 4Health News:Career in Eye Care Practical Compared to Rising Tuition Costs 2Health News:Career in Eye Care Practical Compared to Rising Tuition Costs 3Health News:Career in Eye Care Practical Compared to Rising Tuition Costs 4Health News:Career in Eye Care Practical Compared to Rising Tuition Costs 5Health News:The UK's Biggest Card Retailer Takes Choice and Value Personally 2Health News:The UK's Biggest Card Retailer Takes Choice and Value Personally 3Health News:The UK's Biggest Card Retailer Takes Choice and Value Personally 4Health News:New Online Beauty Store Suggests Stem Cells for the Woman Who Has Everything 2Health News:Give the Gift of Service This Holiday Season with Delegate Source 2Health News:Give the Gift of Service This Holiday Season with Delegate Source 3
... may be able to control how much a husband indulge ... However the reverse may not always be true., ,Researchers ... marriage for 20-somethings, husbands were more likely to start or ... were more likely to stop smoking marijuana if their spouses ...
... multivitamin supplement in the belief that they are// doing ... a recent survey suggests that too much vitamin A ... women do not consider the vitamin's presence in most ... The survey conducted by Oxfordshire brand of the UK's ...
... Immunodeficiency Virus caused by the virus Human Immunodeficiency Virus has ... more than 5 million adults and children are living with ... is estimated that world wide 39.4 million people will be ... team from the University of Kumamoto has found a new ...
... conducted recently links dark chocolate consumption to improved insulin ... ounces of dark chocolate a day for several weeks ... and improves insulin sensitivity in patients with hypertension., ... women, each were assigned 3.5 ounces of dark chocolate ...
... of microRNAs may be responsible for birth defects, cancer ... Genetics Institute have used genetically modified mice to see ... of animals. When the mice were grown without the ... nonfunctional limbs., ,MicroRNA (miRNA) are small RNA molecules ...
... practice of yoga can reduce the bulging girth of the abdomen ... Hutchinson Cancer Research Center who have conducted a study showed that ... for four or more years can lead to arrest of weight ... looked into the data collected from 15,500 men and women in ...
Other Medicine News:Health News:Wife May Determine Husband’s Marijuana Use 2Health News:New Drug To Fight AIDS 2
The ExcaliburPlus PC is the most powerful isolated ESU with 10,000 V PTP in spray coag....
Designed to use all advantages of bipolar technique. C-2600 MP recommended to all specialties that uses the benefits of the bipolar techniques....
Finesse electrosurgical generator (100-120 VAC) utilizes a patented design that integrates the electrosurgical generator and smoke evacuation system into a single compact unit....
The Aaron 800-EU is designed and engineered to be the most reliable and durable desiccator available today....
Medicine Products: