Navigation Links
ACE-011 Improves Multiple Myeloma Bone Disease in a Preclinical,Model

are for a phase 2 clinical trial in multiple myeloma later this year".

Acceleron is developing therapeutics that addresses the clinical consequences of cancer, such as bone loss and/or muscle loss, as well as treatments that directly target the underlying tumor. Given the improving therapeutic outcomes leading to more cancer patients living longer with their disease, the frequency of secondary consequences of cancer is increasing.

About ACE-011

ACE-011, a novel bone anabolic agent currently in a phase 1 clinical trial, is a protein therapeutic based on the activin receptor IIA. In numerous preclinical models of bone loss, ACE-011 has demonstrated beneficial effects on both trabecular and cortical bone. ACE-011 increased bone mineral density, improved bone architecture, increased the mineral apposition and bone formation rates and improved bone mechanical strength. These effects have been demonstrated in therapeutic models of bone loss in which ACE-011 has stimulated bone formation - a significant unmet medical need that is underserved by current treatments for bone loss.

About Multiple Myeloma

Multiple myeloma is a malignancy of plasma cells in the bone marrow that disrupts normal bone marrow function. Myeloma cells invade and destroy the bone surrounding the marrow cavity leading to rapid and widespread osteoporosis and osteolytic bone lesions, resulting in fractures, vertebral compressions and bone pain. Intravenous bisphosphonates are the current standard of care, but significant unmet medical need remains since most patients will still have serious bone complications despite treatment. According to the International Myeloma Foundation, there are an estimated 750,000 people worldwide multiple myeloma. In the US and EU, there are approximately 80,000 myeloma patients whose disease has affected their bones.

About Acceleron Pharma

Acceleron is a privately held biopharmaceutical company committed to discover, develop,
'"/>




Page: 1 2 3

Related medicine technology :

1. Mayo Clinic News Release: Mayo Clinic-led Study Improves Breast Cancer Risk Prediction in Women with Atypia
2. Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal Women with Early Breast Cancer Receiving Treatment with Tamoxifen
3. Actemra (tocilizumab) Significantly Improves Symptoms of Rheumatoid Arthritis Compared to a Current Standard of Care
4. Data Presented at SLEEP 2007 Shows VEC-162 Improves Sleep Onset and Maintenance vs. Placebo
5. Ivivis PEMF Technology Significantly Improves Neuron Survival in Parkinsons Disease Model, Study Finds
6. Study Shows Velcade Plus Doxil Improves Survival in Previously Treated Patients With Multiple Myeloma
7. Adding Thalidomide to Standard Therapy Improves Survival in Newly Diagnosed Multiple Myeloma Patients Over Age 75
8. First-of-Its-Kind Study Shows Botox (Botulinum Toxin Type A) Significantly Improves Idiopathic Detrusor Overactivity (IDO) in Patients With Symptoms of Overactive Bladder
9. Newly Published Study Reveals Femara Improves Chances for Harder to Treat Early Breast Cancer Relapse in Postmenopausal Women
10. Once Daily, Extended-Release Ropinirole Improves Parkinsons Symptoms in Patients not Optimally Controlled With Levodopa
11. Keryx Biopharmaceuticals, Inc. Announces Positive Phase I and Phase II Data on KRX-0401 in Patients with Relapsed/Refractory Multiple Myeloma and Waldenstroms Macroglobulinemia
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: ACE Improves Multiple Myeloma Bone Disease Preclinical Model
(Date:5/1/2015)... , May 1, 2015 Hitachi Chemical Diagnostics, ... States launch of the ExoComplete™ 96-Well Plate ... easy system for exosome collection to mRNA purification.  The ... Vesicles ("ISEV") Annual Meeting, April 23 – 26, 2015, ... are intended for research use only of molecular biology ...
(Date:5/1/2015)... May 1, 2015 Following yesterday,s release of Center ... here are five things you need to know: ... structure is unique among government programs. ... is different than other parts of Medicare and other government ... submit bids to offer prescription drug benefits to enrollees. ...
(Date:5/1/2015)... CAMBRIDGE, Mass. , May 1, 2015  Portal ... innovative drug delivery systems, announced today that Robert ... Hunter , Ph.D., University of Auckland Distinguished Professor have ... are thrilled to welcome two esteemed biotechnology leaders, Professor ... , to our team," said Dr. Patrick Anquetil ...
Breaking Medicine Technology:New Products for Exosome Isolation to mRNA Purification 25 Things to Know About the CMS Part D Data Release 25 Things to Know About the CMS Part D Data Release 3Portal Instruments Adds Two Esteemed Biotechnology Leaders to its Scientific Advisory Board 2Portal Instruments Adds Two Esteemed Biotechnology Leaders to its Scientific Advisory Board 3Portal Instruments Adds Two Esteemed Biotechnology Leaders to its Scientific Advisory Board 4
(Date:5/2/2015)... 2015 On Tuesday April 7th, the ... gathered to celebrate improvements in patient care. In 2014 ... (RVHP), had zero acquired ventilator associated infections, zero central ... ELCH was also recently named a Top Performer by ... ELCH credited the teamwork of staff from all departments ...
(Date:5/1/2015)... IDLife LLC, a health and wellness ... the addition of its newest partner and fitness celebrity, ... athlete, growing up in gymnastics and competitive diving, but ... a personal trainer and helping others achieve their fitness ... TV shows highlighting her stunning physique and unique training ...
(Date:5/1/2015)... (PRWEB) May 01, 2015 The ... leading nonprofit authority on the use of health IT ... a key contributing resource to the United States Government ... of electronically readable cards in Medicare. The report, “ ... Providers ” was released to the public on Apr. ...
(Date:5/1/2015)... The fields of genetics and genomics, the ... genes with one another and the environment, is rapidly ... LabRoots, the premier producer of interactive virtual events for ... its annual conference spotlighting the recent advances in Genetics ... Genomics 2015 , a two-day event presented entirely online ...
(Date:5/1/2015)... May 01, 2015 The frozen yogurt ... the Hickory Crawdads (NC) and the Myrtle Beach Pellicans ... in-stadium concession locations and offer fans discounts at local ... the Hickory Community,” said Luke Shook, co-owner of the ... opportunity and we look forward to enjoying the games ...
Breaking Medicine News(10 mins):Health News:East Liverpool City Hospital Celebrates Patient Care Improvements 2Health News:IDLife LLC Announces New Partnership with Fitness Celebrity, Jen Widerstrom 2Health News:WEDI Contributes to Newly Released U.S. Government Accountability Office (GAO) Study on Potential Use of Electronically Readable Medicare Cards 2Health News:WEDI Contributes to Newly Released U.S. Government Accountability Office (GAO) Study on Potential Use of Electronically Readable Medicare Cards 3Health News:Recent Advances in Genetics and Genomics: A BioConference Live 2015 Virtual Event 2Health News:Recent Advances in Genetics and Genomics: A BioConference Live 2015 Virtual Event 3Health News:sweetFrog Announces Minor League Baseball Partnerships 2
... Insurance,Holdings, Inc. (Nasdaq: EIHI ) ("EIHI," the "Company") ... $0.05 per share quarterly cash,dividend on its issued and ... shareholders of record at the close of business on,December ... Eastern Life and Health Insurance Company,("Eastern Life and Health"), ...
... 2 Clinical Trials,Dow AgroSciences CEO Discusses Future Opportunities with ... BioSciences, Inc.,(Nasdaq: SGMO ) announced that the company ... preview objectives for 2008 during its,annual Investor and Analyst ... Peribere, President and CEO of Dow AgroSciences will discuss ...
... IDEV ) today announced the Company will be ... 13, 2007 at 12:30 PM,Eastern Time. The conference is ... web cast live and may be accessed by visiting ... ., About Indevus, Indevus Pharmaceuticals, Inc. is ...
... ROCKVILLE, Md., Dec. 5 An array of ... and others,reduce medical errors was released today by ... 17 toolkits, developed by AHRQ-funded experts who specialize ... can be adapted,to most health care settings. The ...
... a more complicated medical case, what makes different ... patients" Researchers at UC Davis have identified several ... length of a patients medical appointment, and ultimately ... , In a new study, "Primary Care ...
... markers play a role, and the condition can be inherited ... News) -- A U.S. team has spotted nine genetic markers ... also found evidence that the condition can be inherited in ... parents. , "If a person inherits identical copies of these ...
Cached Medicine News:Health News:Eastern Insurance Holdings, Inc. Announces Quarterly Dividend 2Health News:Eastern Insurance Holdings, Inc. Announces Quarterly Dividend 3Health News:Sangamo BioSciences Provides Update on Company's Accomplishments in 2007 and 2008 Objectives 2Health News:Sangamo BioSciences Provides Update on Company's Accomplishments in 2007 and 2008 Objectives 3Health News:Sangamo BioSciences Provides Update on Company's Accomplishments in 2007 and 2008 Objectives 4Health News:Sangamo BioSciences Provides Update on Company's Accomplishments in 2007 and 2008 Objectives 5Health News:Sangamo BioSciences Provides Update on Company's Accomplishments in 2007 and 2008 Objectives 6Health News:Sangamo BioSciences Provides Update on Company's Accomplishments in 2007 and 2008 Objectives 7Health News:Indevus Pharmaceuticals To Present at RBC Capital Markets Conference 2Health News:Indevus Pharmaceuticals To Present at RBC Capital Markets Conference 3Health News:AHRQ Releases Toolkits to Help Providers and Patients Implement Safer Health Care Practices 2Health News:New UC Davis study finds physician style and HMO affiliation impact lengths of patient visit 2Health News:Genes Yield More Clues to Schizophrenia 2
... monitoring for intermediate care., ,The S/5 FM ... Datex-Ohmeda S/5 product line., ,The S/5 FM ... power to grow. The new Patient Side Module ... up to 12-lead ECG, NIBP, motion-tolerant SpO ...
... ,The Datex-Ohmeda S/5 Light Monitor is a ... and critical care areas, in emergency or medium-care ... part of the Datex-Ohmeda S/5 family, the S/5 ... and design shared by all S/5 monitoring products ...
... ,The S/5 Anesthesia Monitor (AM) is a ... solution for routine to the most demanding anesthesia ... you can choose the set of parameters that ... your needs evolve, the modularity of the S/5 ...
... Golden Standard in Metabolic Monitoring, ,The ... in a compact, easy-to-use bedside unit. It's ... a canopy and is equally suited to ... of all ages., ,The individual nutritional ...
Medicine Products: