Navigation Links
2007 ASCO Annual Meeting: Clinical Results on Phase IIb-study with,AP 12009 in Anaplastic Astrocytoma selected for Poster Discussion

REGENSBURG, Germany, May 10th, 2007 - Antisense Pharma, a German biopharmaceutical company specialized in targeted therapies for malignant tumors, today announced, that data from the Phase IIb-study with AP 12009 in high-grade glioma will be presented at the 43rd Annual Meeting of the American Society of Clinical Oncology (ASCO), which will be held in Chicago, Illinois, U.S.A, from June 1st - 5th.

In the open-label, randomized dose-finding Phase IIb-trial adult patients with recurrent or refractory high-grade glioma were treated either with one of two doses of the TGF-beta2 inhibitor AP 12009 - applied by convection-enhanced delivery - or chemotherapy (temozolomide or PCV) as a control. Survival data in the subgroup of anaplastic astrocytoma patients suggest superiority of AP 12009 over chemotherapeutic treatment.

Median overall survival has not yet been reached in both AP 12009 dose groups in contrast to 91 weeks in the chemotherapy treatment group. Overall response rates demonstrate a benefit of AP 12009 over chemotherapy. The duration of long-term tumor responses until now exceeds the active treatment period by far.

“The significance of our clinical research findings is reflected by the fact, that the Scientific Program Committee has chosen the data for poster discussion among many high quality abstracts”, says the coordinating investigator of the study, Prof. Ulrich Bogdahn, MD, University of Regensburg, Germany. Data from the Phase IIb-study on efficacy and safety in anaplastic astrocytoma patients will be discussed by Albert J. Wong, MD on Sunday June 3rd 2007 in the session “Central Nervous System Tumors” from 11:15 a.m. to 11:30 a.m. in room S100a on Level 1 of McCormick Place South Building.

Prof. Bogdahn will be available for further discussion at the poster entitled “A Phase IIb actively controlled study with the TGF-beta2 inhibito
'"/>




Page: 1 2 3

Related medicine technology :

1. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
2. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
3. Generex Biotechnology to Make Presentations At 46th Annual Meeting of the European Society of Pediatric Endocrinology
4. Micromet, Inc. to Present at the 3rd Annual C.E. Unterberg, Towbin Emerging Growth Conference
5. Neurologix to Present at the Third Annual C.E. Unterberg Towbin Emerging Growth Conference
6. BioLife Solutions Presents Data on CryoStor at International Society for Cellular Therapy Annual Meeting
7. Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Associations Annual Meeting
8. MaxCyte and Medinet to Present at the 13th Annual Meeting of the International Society for Cellular Therapy (ISCT) in Sydney, Australia
9. ConjuChem Biotechnologies Reports PC-DAC:Exendin-4 Albumin Conjugate Data Presented at American Diabetes Association Annual Meeting
10. Ambrilia Highlights Encouraging Data for its HIV Integrase Inhibitor Program and Recent Developments at Annual Meeting
11. Neurogen Proprietary Insomnia Compound Data for Two Studies Presented at Associated Professional Sleep Societies Annual Meeting

Post Your Comments:
(Date:11/6/2009)... Nov. 6 America,s Speci...ng group of mid-market and smaller innovator pharm...t H.R. 3962, the "Affordable Health Care for Ameri...ay. These smaller companies fear that the cumulat...ll hinder their efforts to bring new medicines to ...
(Date:11/6/2009)...Ky., Nov. 6 Virtual Heal...onfirmed today that the previously confirmed Lette... to Wound Management Technologies, Inc (WNDM) is s...s and shareholders of VHGI. ,, Shareholder A...ock dividend, royalty stream and cash realized fro...
(Date:11/6/2009)...IANGLE PARK, N.C., Nov. 6 Chimerix...ly-available antiviral therapeutics to address lif...evelopment of the company,s lead antiviral compoun...and the Global Health Security Initiative (GHSI). ...developed for the treatment of smallpox, as well a...
Breaking Medicine Technology:Statement of America's Specialty Medicines Companies On House Health Care Bill (H.R. 3962) 2OTCBB-VHGI Updates Shareholders on Status of Healthcare Asset Sale and Treasure Gulch Gold Mine Development Strategy 2OTCBB-VHGI Updates Shareholders on Status of Healthcare Asset Sale and Treasure Gulch Gold Mine Development Strategy 3OTCBB-VHGI Updates Shareholders on Status of Healthcare Asset Sale and Treasure Gulch Gold Mine Development Strategy 4Chimerix Updates the World Health Organization and the Global Health Security Initiative on Development of CMX001 as a Broad-Spectrum Therapeutic for Smallpox 2Chimerix Updates the World Health Organization and the Global Health Security Initiative on Development of CMX001 as a Broad-Spectrum Therapeutic for Smallpox 3Weeding out marijuana 3A Researchers close in on engineering recognizable drug free Cannabis plant 9933 1Weeding out marijuana 3A Researchers close in on engineering recognizable drug free Cannabis plant 9933 2Bausch 26 Lomb SofLens 28R 29 Daily Disposable Contact Lenses Partners with Shutterfly to Find the Most Eye Catching Photo of the Summer 57212 1Bausch 26 Lomb SofLens 28R 29 Daily Disposable Contact Lenses Partners with Shutterfly to Find the Most Eye Catching Photo of the Summer 57212 2Family Health Premiums Reach 2413 375 Annually in 2009 Up 5 Percent as Inflation Fell Nearly 1 Percent 57207 1Family Health Premiums Reach 2413 375 Annually in 2009 Up 5 Percent as Inflation Fell Nearly 1 Percent 57207 2Family Health Premiums Reach 2413 375 Annually in 2009 Up 5 Percent as Inflation Fell Nearly 1 Percent 57207 3Family Health Premiums Reach 2413 375 Annually in 2009 Up 5 Percent as Inflation Fell Nearly 1 Percent 57207 4Family Health Premiums Reach 2413 375 Annually in 2009 Up 5 Percent as Inflation Fell Nearly 1 Percent 57207 5Family Health Premiums Reach 2413 375 Annually in 2009 Up 5 Percent as Inflation Fell Nearly 1 Percent 57207 6
...l., July 17 The research team at the,Nemours Cent...established,division of Nemours Biomedical Researc...s discovered that the biomarker called prostate sp... in cancer cells of patients,with advanced prostat...on,of cancer to an aggressive disease. A biomarker...
...MC278, the third anti-HIV compound to be developed...folio -, YARDLEY, Pa., July 17 Tibotec Pharmaceu...II efficacy trials examining TMC278,its investigat...or (NNRTI),in treatment-naive adults with HIV-1, a... compare the efficacy, safety and tolerability of ...
Other Medicine Technology:Nemours Center for Childhood Cancer Research Team at the Alfred I. duPont Hospital for Children Identifies the Function of a Biomarker Present in Prostate Cancer Cells: New Insight into Therapeutic Benefit for Patients with Advanced Prostate Cancer 2Nemours Center for Childhood Cancer Research Team at the Alfred I. duPont Hospital for Children Identifies the Function of a Biomarker Present in Prostate Cancer Cells: New Insight into Therapeutic Benefit for Patients with Advanced Prostate Cancer 3Tibotec Conducts Two Pivotal Phase III Clinical Trials Studying TMC278 in Treatment-Naive Adults with HIV 2Tibotec Conducts Two Pivotal Phase III Clinical Trials Studying TMC278 in Treatment-Naive Adults with HIV 3
(Date:11/6/2009)..., VANCOUVER, Nov. 6 /PRNewswire-FirstCall/ - Cardi... announced that it will report financial results f...he morning of Monday, November 9, 2009. Cardiome w...am Eastern (6:00am Pacific) on that day to discuss...ease dial 416-695-7806 or 888-789-9572 and referen...
(Date:11/6/2009)... COLUMBUS, Ohio, Nov. 6 Authentidate Holding Corp... Health Information Exchange and workflow manageme...ws Inscrybe® Healthcare to be easily integrat...ormation systems, Definitive Homecare Solutions, C...the CPR+ Integrated Solutions Provider program, a ...
(Date:11/6/2009)... The Leukemia & Lymphoma Society (LLS) wi... Get program, which in its first two campaigns thi...llion to support LLS,s blood cancer research fundi...During the campaign, taking place from November 12... discount coupons participants can use (in-store...
(Date:11/6/2009)... Healthcare Trust of America, Inc. (the "REIT"), a...trust, announced the execution of a Purchase and S...al office building located in Englewood, Colorado ...ce Medical Center is located within the Englewood ...opment district. Hampden Place is located near the...
(Date:11/6/2009)...S. bishops sent an urgent message to the U.S. Hous...steeped themselves in debate over procedures relat... Moments before meeting to discuss proposed amendm...rocess" that would permit discussion of "an amendm...on funding and conscience protections." Some in th...
Breaking Medicine News(10 mins):Health News:Cardiome to Release Third Quarter Results 2Health News:Cardiome to Release Third Quarter Results 3Health News:Authentidate Introduces New Interface for Inscrybe Healthcare with Definitive Homecare Solutions' CPR+ 2Health News:Authentidate Introduces New Interface for Inscrybe Healthcare with Definitive Homecare Solutions' CPR+ 3Health News:Authentidate Introduces New Interface for Inscrybe Healthcare with Definitive Homecare Solutions' CPR+ 4Health News:Get a Jump on Your Holiday Shopping and Give Two Gifts This Season: One to Your Loved Ones and One to People Battling Blood Cancer 2Health News:Healthcare Trust of America, Inc. Executes Agreement to Acquire a 66,339 SF Medical Office Building Located in Englewood, Colorado 2Health News:Healthcare Trust of America, Inc. Executes Agreement to Acquire a 66,339 SF Medical Office Building Located in Englewood, Colorado 3Health News:Bishops to House: Keep Abortion Funding Out of Health Care Reform, Make Health Care Available to Vulnerable 2Health News:Bishops to House: Keep Abortion Funding Out of Health Care Reform, Make Health Care Available to Vulnerable 3Health News:Bishops to House: Keep Abortion Funding Out of Health Care Reform, Make Health Care Available to Vulnerable 4Health News:Bishops to House: Keep Abortion Funding Out of Health Care Reform, Make Health Care Available to Vulnerable 5
...sounds like the theme of a cartoon series but it i...esearch being conducted at the University of,Delaw...the cognitive,development of infants with special ...g -,have outfitted kid-size robots to provide mobi...
...ny,s,commitment to encourage healthier lifestyle c... today for the amendment to the Farm Bill that wou...hools proposed by Senate,Agriculture Committee Cha...mprove the nutrition environment in schools. The,C...
...ses in plan premiums,drug costs; urges beneficiari...ent period, WASHINGTON, Nov. 9 Halloween may be ...ring open enrollment could be,in for a nasty scare...al Security checks., "Anyone currently enrolled i...
..., non-profit organization offering free mental hea... ones, announces there are 750,providers nationwid...to its network 10 percent, or 40,000,people, of th...nd the taxpayer $4 million per week in mental heal...
...es, a burst abdominal aortic artery is quickly fat...w study -- the largest yet performed -- now confir... heart disease are also at high risk for an abdomi.... , The findings, reported in the Journal of Vasc...
...LSE: SHP, NASDAQ: SHPGY, TSX: SHQ), the global spe...ced results of a national survey where 60 percent ...ds once-daily Attention Deficit Hyperactivity Diso...ration of effectiveness of their childs once-daily...
Other Medicine News:Health News:Babies Driving Robots at University 2Health News:Babies Driving Robots at University 3Health News:Babies Driving Robots at University 4Health News:Babies Driving Robots at University 5Health News:Babies Driving Robots at University 6Health News:Mars US Supports Harkin/Murkowski Amendment to Update Nutrition Standards for Foods Sold in Schools 2Health News:Cha-Ching! Seniors Enrolled in Medicare Prescription Drug Plans Might Be in for Sticker Shock Next Year 2Health News:Cha-Ching! Seniors Enrolled in Medicare Prescription Drug Plans Might Be in for Sticker Shock Next Year 3Health News:Cha-Ching! Seniors Enrolled in Medicare Prescription Drug Plans Might Be in for Sticker Shock Next Year 4Health News:Non-Profit Calls on Mental Health Professionals to Honor Veterans Day by 'Giving an Hour' of Free Counseling to Returning Veterans 2Health News:Screening for abdominal aortic aneurysms in women may save lives 2Health News:Screening for abdominal aortic aneurysms in women may save lives 3Health News:Parents survey: Perceptions of the duration of their child's ADHD medication 2
Microforceps: End-gripping
Titanium Microforceps: Side-gripping
...D.O.R.C. Microdiathermy System features an advance...6 MHz. Research, as well as many years of clinical... optimum choice for the placement of discrete burn... produce the maximum effect at the target tissue w...
FC-2000 Flare Meter
Medicine Products: