Navigation Links
2007 ASCO Annual Meeting: Clinical Results on Phase IIb-study with,AP 12009 in Anaplastic Astrocytoma selected for Poster Discussion

REGENSBURG, Germany, May 10th, 2007 - Antisense Pharma, a German biopharmaceutical company specialized in targeted therapies for malignant tumors, today announced, that data from the Phase IIb-study with AP 12009 in high-grade glioma will be presented at the 43rd Annual Meeting of the American Society of Clinical Oncology (ASCO), which will be held in Chicago, Illinois, U.S.A, from June 1st - 5th.

In the open-label, randomized dose-finding Phase IIb-trial adult patients with recurrent or refractory high-grade glioma were treated either with one of two doses of the TGF-beta2 inhibitor AP 12009 - applied by convection-enhanced delivery - or chemotherapy (temozolomide or PCV) as a control. Survival data in the subgroup of anaplastic astrocytoma patients suggest superiority of AP 12009 over chemotherapeutic treatment.

Median overall survival has not yet been reached in both AP 12009 dose groups in contrast to 91 weeks in the chemotherapy treatment group. Overall response rates demonstrate a benefit of AP 12009 over chemotherapy. The duration of long-term tumor responses until now exceeds the active treatment period by far.

“The significance of our clinical research findings is reflected by the fact, that the Scientific Program Committee has chosen the data for poster discussion among many high quality abstracts”, says the coordinating investigator of the study, Prof. Ulrich Bogdahn, MD, University of Regensburg, Germany. Data from the Phase IIb-study on efficacy and safety in anaplastic astrocytoma patients will be discussed by Albert J. Wong, MD on Sunday June 3rd 2007 in the session “Central Nervous System Tumors” from 11:15 a.m. to 11:30 a.m. in room S100a on Level 1 of McCormick Place South Building.

Prof. Bogdahn will be available for further discussion at the poster entitled “A Phase IIb actively controlled study with the TGF-beta2 inhibito
'"/>




Page: 1 2 3

Related medicine technology :

1. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
2. Halozyme Therapeutics Enhanze Technology Large Protein Molecule Therapeutic Clinical Trial Results Presented at the 34th Annual Meeting of the Controlled Release Society
3. Generex Biotechnology to Make Presentations At 46th Annual Meeting of the European Society of Pediatric Endocrinology
4. Micromet, Inc. to Present at the 3rd Annual C.E. Unterberg, Towbin Emerging Growth Conference
5. Neurologix to Present at the Third Annual C.E. Unterberg Towbin Emerging Growth Conference
6. BioLife Solutions Presents Data on CryoStor at International Society for Cellular Therapy Annual Meeting
7. Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Associations Annual Meeting
8. MaxCyte and Medinet to Present at the 13th Annual Meeting of the International Society for Cellular Therapy (ISCT) in Sydney, Australia
9. ConjuChem Biotechnologies Reports PC-DAC:Exendin-4 Albumin Conjugate Data Presented at American Diabetes Association Annual Meeting
10. Ambrilia Highlights Encouraging Data for its HIV Integrase Inhibitor Program and Recent Developments at Annual Meeting
11. Neurogen Proprietary Insomnia Compound Data for Two Studies Presented at Associated Professional Sleep Societies Annual Meeting
Post Your Comments:
(Date:5/27/2015)... , May 27, 2015 ... has announced the addition of the  "2015 ... Market"  report to their offering.  ... comprehensive five-country report contains 500 pages, 120 ... suppliers and potential market entrants identify and ...
(Date:5/27/2015)... , May 27, 2015 Protein purification ... based on differences in their physical properties. The objective ... largest amount of functional protein with fewest contaminants. The ... grow at a CAGR of around 5% to 6% ... by increased research in the pharmaceutical and biotechnological fields, ...
(Date:5/27/2015)... DUBLIN , May 27, 2015 /PRNewswire/ ... ) has announced the addition of the  ... Trends And Forecasts (2014 - 2019)" ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , , ,Ultrasound is ... sound waves to look at body parts ...
Breaking Medicine Technology:European Hemostasis Diagnostic Testing Market Strategies 2015 2Protein Purification & Isolation Market by Technology by Product by Application & End User - Global Forecast to 2020 2Protein Purification & Isolation Market by Technology by Product by Application & End User - Global Forecast to 2020 3Asia Pacific Ultrasound Devices Market Report 2015 - Growth, Trends And Forecasts 2014 - 2019 2
... ANNAPOLIS, Md., April 13, 2011 PharmAthene, Inc. (NYSE ... has completed dosing in a U.S. Phase I clinical ... being developed for the prevention and treatment of inhalational ... clinical trial was designed to evaluate single escalating doses ...
... HONOLULU, April 13, 2011 Today, GE Healthcare announced ... the impact of DaTscan™ SPECT imaging on the clinical ... or symptoms of parkinsonian syndromes (PS). The results, presented ... an important step in documenting the value of DaTscan ...
Cached Medicine Technology:PharmAthene Completes Dosing in Valortim® Phase I Clinical Trial 2PharmAthene Completes Dosing in Valortim® Phase I Clinical Trial 3GE Healthcare Presents Interim Data on the Impact of DaTscan™ (Ioflupane I 123 Injection) SPECT Imaging on the Diagnosis and Clinical Management of Patients with Clinically Uncertain Parkinsonian Syndrome 2GE Healthcare Presents Interim Data on the Impact of DaTscan™ (Ioflupane I 123 Injection) SPECT Imaging on the Diagnosis and Clinical Management of Patients with Clinically Uncertain Parkinsonian Syndrome 3GE Healthcare Presents Interim Data on the Impact of DaTscan™ (Ioflupane I 123 Injection) SPECT Imaging on the Diagnosis and Clinical Management of Patients with Clinically Uncertain Parkinsonian Syndrome 4GE Healthcare Presents Interim Data on the Impact of DaTscan™ (Ioflupane I 123 Injection) SPECT Imaging on the Diagnosis and Clinical Management of Patients with Clinically Uncertain Parkinsonian Syndrome 5GE Healthcare Presents Interim Data on the Impact of DaTscan™ (Ioflupane I 123 Injection) SPECT Imaging on the Diagnosis and Clinical Management of Patients with Clinically Uncertain Parkinsonian Syndrome 6
(Date:5/27/2015)... 27, 2015 The BBB Code of ... practices that enhance customer trust and confidence in business. ... Trust, eight principles that summarize important elements of creating ... standards for business accreditation by BBB. Businesses based in ... and complete application procedures will be accredited by BBB. ...
(Date:5/27/2015)... May 27, 2015 With the launch ... more robust Network Management Module (NMM) tool, monitoring provider-network ... 21 issue of Atlantic Information Services, Inc.’s (AIS) Medicare ... NMM tool, as well as analysis from industry experts ... The changes coming to the NMM were announced at ...
(Date:5/27/2015)... Austin, TX (PRWEB) May 27, 2015 ... gas information. Topics include: Why investors should consider oil ... investors, how and why wells are drilled, industry news, ... , Carson Energy's 32 years of knowledge and experience ... and gas investment community to be able to access ...
(Date:5/27/2015)... May 27, 2015 The Case ... a partnership to provide CMSA's Career and Knowledge ... collaboration seeks to strengthen the case/care management workforce ... CKP program. The mutually beneficial agreement provides Medix, ... skills of talent in the healthcare, scientific and ...
(Date:5/27/2015)... (PRWEB) May 27, 2015 Coco Libre announced ... be able to reach for Organic Coconut Water to quench ... will be available at VIP areas, artist greenrooms, corporate skyboxes ... available at area hotels and on festival shuttle buses. ... this year,” said Noa Elan, Director of Strategic Partnerships for ...
Breaking Medicine News(10 mins):Health News:Carson Energy Receives A+ Accredited Rating For 19 Consecutive Years 2Health News:AIS Newsletter Offers Coverage, Analysis of New CMS Strategy on Monitoring MA Provider Access 2Health News:AIS Newsletter Offers Coverage, Analysis of New CMS Strategy on Monitoring MA Provider Access 3Health News:Carson Energy Launches Next Generation Investor Website 2Health News:Case Management Society of America Partners with Medix to Offer Career and Knowledge Pathways 2Health News:Case Management Society of America Partners with Medix to Offer Career and Knowledge Pathways 3Health News:Coco Libre Puts Organic Coconut Water on the Line-up at BottleRock Napa 2
... New Zealand Aids Foundation has welcomed a decision by Pharmac(the ... the same time, they say delays over the funding may ... medicines, to be subsidized from April 1, 2007 are Tenofovir ... to Pharmac’s medical director Dr Peter Moodie the investment would ...
... slower in children who wear a special kind of ... lenses// according to a new study published in Investigative ... found that among children with two myopic parents, myopia ... when compared to those wearing single-vision lenses (SVLs).Knowing parental ...
... by a specialist headache centre, it was observed that eight ... at work; 91 per cent blamed the ineffectiveness to headaches, ... published in the March issue of Cephalalgia. ,"Migraines ... when they are often at their most productive, so the ...
... suggests that genes responsible for generating matrix metalloproteinase 1 ... long term hip replacement surgery. ,The researchers ... of whom (162) had problems after hip replacement in ... with symptoms, 91 had early signs of 'aseptic loosening,' ...
... SAN DIEGO--(BUSINESS WIRE)--Ichor Medical Systems, whose advanced electroporation ... effectiveness// of DNA drug and vaccine delivery, has ... $900,000 by the United States Department of Defense ... Institute of Infectious Diseases (USAMRIID) in Fort Detrick, ...
... certainly be an indicator of one’s happiness. Researchers at the ... nation's overall happiness and its citizens' blood pressure problems. ... across the European countries. ,These people were asked how happy ... blood pressure) and so on. ,While Sweden, Denmark ...
Cached Medicine News:Health News:New Zealand’s Pharmac Subsidies Two More HIV Drug 2Health News:Work Absence Due to Headaches Has a Substantial Socio-economic Effect 2Health News:United States Department of Defense Selects Ichor Medical Systems to Develop Biodefense Vaccine 2
Midstream Catch Kits...
... a portable, noninvasive ultrasound instrument that measures ... use, and quickly provides accurate results. In ... the BladderScan® to obtain a precise reading ... supplies the information that caregivers need to ...
... The BladderScan® BVI 6100 is a handheld, ... It is easy to operate, so any ... accurately. To view ultrasound images from exams ... patient records and reimbursement, just log on ...
... BVM 6500 enables physicians ... determine UEBW (ultrasound estimated ... volume using 3-dimensional V-mode ... was designed to assist ...
Medicine Products: