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Study Shows Novartis Drug Afinitor® Plus Hormonal Therapy Delays Disease Progression in Advanced Metastatic Breast Cancer Patients
Date:12/9/2010

suppl 3):20-29.
  • American Cancer Society. Breast Cancer Detailed Guide. Available at: http://www.cancer.org/Cancer/BreastCancer/DetailedGuide/. Accessed November 2010.
  • US National Institutes of Health. Everolimus in Combination With Trastuzumab and Paclitaxel in the Treatment of HER2 Positive Locally Advanced or Metastatic Breast Cancer (BOLERO-1). http://www.clinicaltrials.gov/ct2/show/NCT00876395?term=BOLERO-1&rank=1. Accessed November 2010.
  • US National Institutes of Health. Everolimus in Combination With Exemestane in the Treatment of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Who Are Refractory to Letrozole or Anastrozole (BOLERO-2). http://www.clinicaltrials.gov/ct2/show/NCT00863655?term=BOLERO-2&rank=1. Accessed November 2010.
  • US National Institutes of Health. Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer (BOLERO-3). http://www.clinicaltrials.gov/ct2/show/NCT01007942?term=BOLERO-3&rank=1. Accessed November 2010.  
  • Afinitor® (everolimus) tablets EU summary of product characteristics. Basel, Switzerland: Novartis International AG; October 2010.
  • Meric-Bernstam et al. Targeting the mTOR Signaling Network for Cancer Therapy. Journal of Clinical Oncology. 2009; 27(13): 2278-2287.
  • World Health Organization. Breast cancer: prevention and control. Available at: http://www.who.int/cancer/detection/breastcancer/en/. Accessed November 2
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