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scPharmaceuticals LLC Announces Strategic Partnership with Sensile Medical to Develop Novel Heart Failure Treatment Aimed to Reduce Readmission Rates
Date:4/7/2013

BOSTON, April 8, 2013 /PRNewswire/ -- scPharmaceuticals LLC today announced that it has entered into a strategic partnership and product development agreement with Sensile Medical Holding AG of Zug, Switzerland to develop an innovative new therapeutic option for patients with heart failure.  The terms of the agreement were not disclosed.

The drug-device combination uses the Sensile SenseCore technology in a wearable minipump that delivers the pharmaceutical drug product under the skin using a very small needle.  The pharmaceutical product is a proprietary reformulation of a proven diuretic that already forms the cornerstone of heart failure therapy.  Diuretics remove excess fluid retained by the body by increasing urinary output.  The diuretic that will be used with the minipump is a novel formulation of the diuretic furosemide, which has been in clinical use for nearly 50 years.  Furosemide is currently used in tablet form or in solution for intravenous administration.  Furosemide required a proprietary reformulation to render it suitable for subcutaneous administration.

Under the product development agreement, Sensile and scPharmaceuticals will collaborate to develop and manufacture minipump devices for use by scPharmaceuticals for its furosemide drug product for subcutaneous administration.  scPharmaceuticals expects to submit its New Drug Application for the furosemide drug device combination no later than Q1 of 2015.

"Hospitalization for heart failure is expected to be one of the most important reasons for the projected increase in health care costs over the next decade as our population ages and the epidemic of obesity and diabetes continues unabated," said Dr. Bertram Pitt , Professor of Medicine Emeritus at the University of Michigan School of Medicine and one of the co-founders of scPharmaceuticals.  "This
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SOURCE scPharmaceuticals LLC
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