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PLC Provides Update on Financing Efforts and RenalGuard(R) Program
Date:2/4/2010

ass="xn-location">Milan (CCM), has completed its original 120 patient enrollment and analysis of the full data is being finalized. The sponsors, who are international experts on CIN, have determined to expand the trial up to 200 patients to gain even stronger scientific proof of the efficacy of RenalGuard in preventing CIN in affected patients.

Meanwhile, the second clinical trial of RenalGuard is ongoing at the Clinica Mediterranea in Naples, Italy, under the sponsorship of Dr. Carlo Briguori, another world-renowned expert on CIN prevention. This trial is anticipated to be completed in late 2010.

About PLC Systems Inc.

PLC Systems Inc. is a medical technology company specializing in innovative technologies for the cardiac and vascular markets. Headquartered in Franklin, Massachusetts, PLC pioneered the CO2 Heart Laser System, which cardiac surgeons use to perform CO2 transmyocardial revascularization (TMR) to alleviate symptoms of severe angina. PLC's newest product, RenalGuard, is approved for sale in the EU as a general fluid balancing device. Additional company information can be found at www.plcmed.com.

This press release contains "forward-looking" statements. For this purpose, any statements contained in this press release that relate to prospective events or developments are deemed to be forward-looking statements. Words such as "believes," "anticipates," "plans," "expects," "will" and similar expressions are intended to identify forward-looking statements. Our statements of our objectives are also forward-looking statements. While we may elect to update forward-looking stateme
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