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-59,165-59,165Total revenue
75,041122,861210,142254,537Operating expenses:Research and development (1) (2)58,53244,568184,071131,394Selling, general and administrative (1)42,64225,924115,34977,293Contingent consideration
5,9455,62223,195101,107Lease termination exit costs
130-10,857-Total operating expenses
107,24976,114333,472309,794Income (loss) from operations
(32,208)46,747(123,330)(55,257)Investment income
4356281,7282,198Interest expense
(5,112)(4,943)(15,155)(14,467)Other income (expense) (3)
25(862)(3,776)(862)Income (loss) before provision (benefit) for income taxes
(36,860)41,570(140,533)(68,388)Provision (benefit) for income taxes
-7032(662)Net (loss) income
$(36,860)$41,500$ (140,565)$ (67,726)Net (loss) income per share:Basic
$
(0.58)$
.66$
(2.22)$
(1.08)Diluted (4)$
(0.58)$
.66$
(2.22)$
(1.08)Computation of diluted shares:Basic
63,55562,70763,32862,562Dilutive effect of options
-142--Diluted (4)63,55562,84963,32862,562(1)Includes employee stock-based compensation charges of:Research and development
$
,988$ 1,075$
4,808$
3,090Selling, general, and administrative
6,6854,79917,56513,502Total employee stock-based compensation
$
8,673$ 5,874$
22,373$ 16,592(2) Includes a $12.7 million non-cash expense related to the unamortized balance of funding provided to S*BIO which was recorded in the first quarter of 2011.
(3) Includes a $3.0 million impairment charge which reflects the reassessment of the fair value of Onyx's equity investment in S*BIO during the first quarter of 2011.
(4) Under the "if-converted" method, interest and issuance costs and potential common shares related to the Company's convertible senior notes were excluded in the computation of diluted per share amounts for the three and
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