Navigation Links
NOVAVAX Presents Final Results from H1N1 Influenza Vaccine Trial at World Health Organization Meeting
Date:2/18/2011

to 85% of subjects which indicates that the VLP vaccine will be important in addressing future influenza pandemics.  Novavax VLPs are unique as they are made in a non-egg-based, recombinant manufacturing system that produces particles resembling the influenza virus but which renders them more immunogenic than simple recombinant vaccines."

Methods

This Phase II randomized, double-blind, placebo-controlled trial was conducted at a single study center in Mexico to evaluate the safety, tolerability, and immunogenicity of 3 dose levels (5mcg, 15mcg, and 45mcg HA) of the novel (H1N1) influenza VLP vaccine as compared with a placebo in healthy adults aged 18 to 64 years.  The study was conducted in two parts: Part A was to evaluate the safety and immunogenicity of the H1N1 influenza VLP vaccine over a dose range and to select a dose for an expanded safety evaluation in Part B. In Part A, 1,013 subjects were enrolled (760 active and 253 placebo). Based on an interim safety and immunogenicity analysis, an additional 3,547 (2,535 active and 1,012 placebo) subjects were enrolled in Part B of the study, a safety only study, and received 15mcg of VLP vaccine or placebo as a single injection on Day 1 using a second lot of H1N1 VLP vaccine.

Safety

In Part A, adverse events (AEs) were similar for the placebo group and for the active vaccine groups, except that dose-related local injection site reactions were reported more frequently in the active vaccine groups.  In Part B of the study, the incidence of AEs was consistent with that of Part A and was comparable between the VLP and placebo groups.  The results for the 15mcg vaccine in Part A and Part B of the study demonstrated that the different vaccine lots exhibited comparable safety profiles.  Across all subjects in Part A and Part B, the majority of AEs were of mild or moderate severity and resolved without sequelae and all serious AEs were considered defin
'/>"/>

SOURCE Novavax, Inc.
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. NOVAVAX to Present H1N1 VLP Influenza Vaccine Clinical Data at 7th World Health Organization (WHO) Meeting on Evaluation of Pandemic Influenza Vaccines in Clinical Trials
2. NOVAVAX Receives FDA Clearance to Launch Phase I RSV Vaccine Clinical Trial
3. NOVAVAX to Present at Lazard 7th Annual Healthcare Conference
4. NOVAVAX Reports Third Quarter 2010 Financial Results
5. Novavax to Report Third Quarter 2010 Financial Results on November 5, 2010
6. NOVAVAX to Present at BIO Investor Forum
7. NOVAVAX to Present at Stifel Nicolaus Conference
8. NOVAVAX Endorses New U.S. Initiatives to Develop Medical Countermeasures
9. NOVAVAX Announces Issuance of Key U.S. Patent for Influenza Virus-Like Particle (VLP) Vaccines
10. Novavax CEO to Present at Phacilitate Vaccine Forum Barcelona 2010
11. Novavaxs Seasonal Influenza VLP Vaccine Candidate Shows Positive Results in a Phase II Clinical Trial in Older Adults
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... 2013  TeamHealth Medical Call Center (THMCC), a ... advice lines, announces its newly formed Clinical Advisory ... administrative leaders, provides clinical expertise to advance THMCC,s ... for hospital clients, physician clients and patients. ... it,s imperative to continuously advance our services and ...
(Date:5/23/2013)... ARBOR, Mich. , May 23, 2013  Every day, ... flow of air to his lungs. April and ... the dire predictions weren,t true. "Quite a few ... the hospital alive," says April Gionfriddo , ... were desperate. Anything that would work, we would take it ...
(Date:5/23/2013)... , May 23, 2013  Ameritox, the ... selected by Progressive Medical, Inc. to become part ... help clients manage pharmacy costs and improve the ... Medical, a leading pharmacy benefit manager in the ... overall medication compliance and pain management strategy for ...
Breaking Medicine Technology:TeamHealth Medical Call Center Forms Clinical Advisory Committee 2Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 2Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 3Baby's life saved with groundbreaking 3D printed device from U-M that restored his breathing 4Ameritox Joins with Progressive Medical in Urine Drug Monitoring Network to Help Improve Care of Injured Workers 2Ameritox Joins with Progressive Medical in Urine Drug Monitoring Network to Help Improve Care of Injured Workers 3
... Meets Primary Endpoint in,Rheumatoid Arthritis Patients Who ... -, NUTLEY, N.J., July 10, 2007 /PRNewswire/ ... Actemra Radiate (RheumAtoiD,ArthritIs Study in Anti-TNF FailurEs) ... with moderate to severe rheumatoid,arthritis (RA) who ...
... Humira Estimated to Increase the,Maximal Steady ... 100%,-, SAN DIEGO, July 09, 2007 ... biopharmaceutical company developing and,commercializing recombinant human ... the Enhanze(TM) Technology clinical trial,demonstrating improved ...
Cached Medicine Technology:Actemra (tocilizumab) Third Phase III Study Results Show,Significant Improvement in Symptoms of Patients with Rheumatoid,Arthritis 2Actemra (tocilizumab) Third Phase III Study Results Show,Significant Improvement in Symptoms of Patients with Rheumatoid,Arthritis 3Actemra (tocilizumab) Third Phase III Study Results Show,Significant Improvement in Symptoms of Patients with Rheumatoid,Arthritis 4Halozyme Therapeutics' Enhanze Technology Large Protein Molecule,Therapeutic Clinical Trial Results Presented at the 34th Annual,Meeting of the Controlled Release Society 2Halozyme Therapeutics' Enhanze Technology Large Protein Molecule,Therapeutic Clinical Trial Results Presented at the 34th Annual,Meeting of the Controlled Release Society 3Halozyme Therapeutics' Enhanze Technology Large Protein Molecule,Therapeutic Clinical Trial Results Presented at the 34th Annual,Meeting of the Controlled Release Society 4Halozyme Therapeutics' Enhanze Technology Large Protein Molecule,Therapeutic Clinical Trial Results Presented at the 34th Annual,Meeting of the Controlled Release Society 5
(Date:5/25/2013)... 2013 The current residents of Back2Basics - ... the B2B staff all came together Saturday, May 18th to ... of Indian Cuisine, the residents got up to thank Roy ... on their road to recovery, and giving them a second ... center in 2010 after realizing the need for a long-term ...
(Date:5/25/2013)... OH (PRWEB) May 25, 2013 The ... filed an Imprelis lawsuit on behalf of 23 ... no. N13C-04-280 EMD) was filed on April 25, 2013 and ... As with previously filed Wright & Schulte Imprelis lawsuits, this ... New Castle County. , This Imprelis lawsuit ...
(Date:5/24/2013)... A recent study by research group Harris Interactive found ... suit season. Almost 138 million people are fearful of pulling ... weight issues and a quarter admit they feel pressured to ... that those anxious about their size consider the over the ... overall effort to improve diet and exercise habits ahead of ...
(Date:5/24/2013)... May 25, 2013 myMEDholiday.com, a popular ... healthcare providers in five important medical travel destinations in ... Patient Guide to ensure a safe and successful ... This 15-step manual offers tips on cost-savings, how to ... your itinerary, and a wealth other essential advice. , ...
(Date:5/24/2013)... Range Kleen Mfg. strives to “TCOTC.” Our ... from the President's desk to the Shipping Dock.” We hold ... and having passion while creating excellence and quality being results ... to do the right thing and what better way to ... by devastation. , Throughout the year Range Kleen donates to ...
Breaking Medicine News(10 mins):Health News:Back2Basics Drug and Alcohol Rehabilitation Center Celebrates Their 3rd Anniversary 2Health News:Imprelis Lawsuit Filed on Behalf of Multiple Property Owners Nationwide Who Allege Imprelis Use Resulted In Extensive Tree Damage and Death, Reports Wright & Schulte 2Health News:Imprelis Lawsuit Filed on Behalf of Multiple Property Owners Nationwide Who Allege Imprelis Use Resulted In Extensive Tree Damage and Death, Reports Wright & Schulte 3Health News:Imprelis Lawsuit Filed on Behalf of Multiple Property Owners Nationwide Who Allege Imprelis Use Resulted In Extensive Tree Damage and Death, Reports Wright & Schulte 4Health News:PhenObestin 37.5 Can Help Make Bathing Suit Season Less Stressful 2Health News:PhenObestin 37.5 Can Help Make Bathing Suit Season Less Stressful 3Health News:myMEDholiday.com Introduces International Patient Guide to Assist People Planning Treatment Abroad 2Health News:Range Kleen Partners with Berndes in Red Cross Promotion: Taking Care of Oklahoma 2
... cell agency made the correct decision today when ... grants because of apparent conflict,of interest violations in ... Taxpayer and Consumer Rights (FTCR) said., The ... resolve the matter, the stem cell agency must ...
... Dec. 7 Legendary blues artists Bobby,Rush and James ... the inaugural Mississippi Blues Marathon and Half-Marathon on Saturday,January ... & Mal,s, located at 200,South Commerce Street, in downtown ... scheduled to go on stage at 8:00 p.m., and ...
... N.C. -- A test for four blood proteins may provide ... chest radiographs or computerized tomography (CT) scans, according to a ... , CT scans have a very high false positive rate ... M.D., a radiologist at Duke and lead investigator on the ...
... Dec. 7 BioHorizons Implant Systems,Inc. relocated ... a,state-of-the- art, 44,000 square foot facility. The ... all administrative services, a newly,formed manufacturing facility ... include machining, surface treatment and packaging services., ...
... As of December 7,2007, Coshocton County Memorial Hospital ... for a 3-year contract. As a result,bargaining unit RNs ... maintain a picket line starting at 7:00 a.m. on ... developed skills and extensive,education. Each and every day they ...
... Relief Survey are in, NEW YORK, Dec. 7 ... breakups anymore. The fast-paced world we live in has,given way ... young,women, face. This trend can be seen in girls all ... some of the factors that contribute,to this new wave of ...
Cached Medicine News:Health News:Stem Cell Institute Correct in Rejecting Applications Over Conflicts of Interest; Institutions, Board Members Involved Must Be Identified, Consumer Advocates Say 2Health News:Stem Cell Institute Correct in Rejecting Applications Over Conflicts of Interest; Institutions, Board Members Involved Must Be Identified, Consumer Advocates Say 3Health News:Study points to possibility of blood test to detect lung cancer 2Health News:BioHorizons Expands to New 44,000 Square Foot Facility 2Health News:Coshocton County Memorial Hospital RNs to Strike Despite Hospital's Claim of Financial Hardship 2Health News:Coshocton County Memorial Hospital RNs to Strike Despite Hospital's Claim of Financial Hardship 3Health News:What Stresses Teens Out 2Health News:What Stresses Teens Out 3
Phaco chopper, a combination of a modified microfinger and a pointed "quick chop" tip. For use in the left hand....
The titanium sleeve is coated with hydroxyapatite (HA) which allows vascular ingrowth, firmly secures the peg in the sphere, and enhances biocompatibility. To hold prosthetic eye. For improved occula...
... Brown nucleus cracker with straight shaft ... viscoelastic, thereby, maintains anterior chamber depth ... Accomplished with a design that keeps ... blocking outflow of viscoelastic. Available with ...
Epilation forceps straight ends size 3.5"....
Medicine Products: