CHAMPAIGN, Ill., April 11, 2011 /PRNewswire/ -- iCyt Mission Technology, Inc. (iCyt), a wholly-owned subsidiary of Sony Corporation of America, today announced the introduction of its new line of 405nm-excited fluorochrome conjugated antibodies for flow cytometry. These new Brilliant Violet™ 421 products are part of the first commercial release of a novel, polymer-based fluorophore technology.
"This exciting new class of fluorescent probes will make significant contributions to the future of flow cytometry, by bringing new power and utility to the violet (405nm) laser," said Gary Durack, CEO of iCyt. "The new Brilliant Violet fluors offer dramatic improvements in brightness and signal-to-noise ratio over the current choices for the violet laser."
In addition to being an order of magnitude brighter than traditional violet excited fluorochromes, this new dye offers greater sensitivity for resolving weakly expressed antigens, and requires less compensation for spectral overlap. Their compatibility with other popular fluorochromes and fluorescent protein combinations offers versatility that will further expand researchers' options for multi-color panels.
The initial iCyt portfolio of anti-mouse and anti-human conjugates have been optimized for use with iCyt's Eclipse™ analyzer and upcoming Synergy™ benchtop sorter, but are compatible with all major commercial flow cytometers equipped with a 405nm laser.
The new BV421 line will include an extensive antibody selection that combines consistent bright staining that is effective for surface and intracellular antigens, with simple, ready-to-use, low volume test size. The new probes are fixation stable and compatible with standard staining buffers.
iCyt intends to continually expand its new line of BV reagents, which complement its already broad portfolio of mouse and human monoclonal antibodies tailored for use in cell biology, immunology, cance
|SOURCE iCyt Mission Technology, Inc.|
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