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iBio Announces Important Expansion of its Intellectual Property Portfolio: Allowance of Patent for Anthrax Vaccines and Further Application of Modulator Platform
Date:6/18/2012

NEWARK, Del., June 18, 2012 /PRNewswire/ -- iBio, Inc. (NYSE AMEX: IBIO) today announced that the US Patent Office has allowed patent application 11/706,576 entitled "Bacillus anthracis Antigens, Vaccine Compositions, and Related Methods."  The claims cover compositions and methods for fusions of sequences of Bacillus anthracis antigens for protective antigen (PA), lethal factor (LF), and edema factor (EF), and combinations thereof to LicKM, which is part of the Company's iBioModulator™ platform.

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Upon issue, this patent will add to iBio's iBioModulator portfolio that includes recently issued US patent 8,173,408 giving broad coverage of the iBioModulator system, and US patent 8,124,103 covering influenza antigens fused to LicKM. The iBioModulator platform has been shown to be applicable to a range of vaccine proteins, and can significantly modify the immune response to a vaccine in two important ways. Animal efficacy studies have demonstrated that it can increase the strength of the initial immune response to a vaccine antigen (as measured by antibody titer) and also extend the duration of the immune response. Thus, the use of the iBioModulator platform may lower vaccine antigen requirements and enable fewer doses to establish prolonged protective immunity.

The ability to provide better immune response and longer-term protection with fewer or zero booster inoculations adds significant value to a vaccine by reducing the overall costs and logistical difficulties of its use. Such improvements in vaccine effectiveness are important for public health reasons and also for bio-defense purposes. For example, the only vaccine for anthrax currently approved for use in the U.S. requires an initial series of five doses t
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SOURCE iBio, Inc.
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