Navigation Links
Halozyme and Intrexon Announce Collaboration to Develop First Subcutaneous Recombinant Alpha 1-Antitrypsin Replacement Therapy
Date:6/6/2011

as a result, treatment for deficiency is limited and expensive. Intrexon will fund all development and commercialization expenses for the program, which is currently in the scale-up phase of process development.

"We are pleased to collaborate with Intrexon on this exciting new endeavor for patients with A1AT deficiency," stated Gregory I. Frost, Ph.D., Halozyme's president and CEO. "The combination of Intrexon's synthetic DNA platform for high-level A1AT production with Halozyme's subcutaneous enzyme technology may enable the first recombinant human A1AT replacement therapy with a more patient-friendly administration profile."

"Halozyme's Enhanze technology is the perfect fit for our recombinant human alpha 1-antitrypsin program," stated Randal J. Kirk, CEO and chairman of the board of Intrexon and board member of Halozyme. Mr. Kirk's comment is seconded by Gerardo Zapata, Ph.D., president of Intrexon's Protein Production Division.  "This collaboration allows us to utilize Halozyme's proprietary protein delivery technology with a subcutaneous recombinant human version of the A1AT protein, an innovative potential therapy for genetic emphysema, COPD, and other diseases caused by A1AT deficiency, and will facilitate our ability to bring a promising novel synthetic biologic treatment alternative to the currently available plasma-derived intravenous products," stated Zapata.

About rHuPH20 Enzyme Technology

Halozyme's proprietary rHuPH20 enzyme facilitates the absorption and dispersion of drugs or fluids that are injected under the skin. When injected under the skin, rHuPH20 transiently generates channels in tissues underlying the outer layers of the skin to increase the absorption and spread of injected drugs. When combined with rHuPH20, molecules as large as 200 nanometers may pass freely through the extracellular matrix, which recovers its normal density within approximately 24 hours, leading to a drug delivery platform t
'/>"/>

SOURCE Halozyme Therapeutics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. Halozyme Therapeutics and ViroPharma Announce $83 Million Global Licensing Agreement to Develop Subcutaneous Cinryze® (C1 esterase inhibitor [human])
2. ViroPharma and Halozyme Announce Collaboration for Combination of Recombinant Human Hyaluronidase Enzyme (rHuPH20) Technology with C1 Esterase Inhibitor
3. Halozyme Therapeutics to Present at the Bank of America Merrill Lynch Health Care Conference on May 12
4. Halozyme Therapeutics to Host First Quarter 2011 Financial Results Conference Call on May 6
5. Halozyme Therapeutics Reports Fourth Quarter and Year End 2010 Financial Results
6. Halozyme Therapeutics to Host Fourth Quarter and 2010 Financial Results Conference Call on March 11
7. Halozyme Therapeutics to Present at J.P. Morgan Healthcare Conference on January 12
8. Halozyme Therapeutics Realigns Management
9. Halozymes rHuPH20 With Recombinant Human Insulin Demonstrates Glycemic Control Comparable to Lispro
10. Halozyme Therapeutics Announces Implementation of Development Focused Strategy
11. Halozyme Therapeutics to Host Analyst Meeting on October 14 in New York
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2013)... , May 20, 2013  Neuralstem, Inc. (NYSE ... , MD, PhD, principal investigator, presented updated Phase ... cell (NSI-566) trial in the treatment of amyotrophic lateral ... disease) at the neuro diabetes special medical symposium in ... a talk called "Recent Therapeutic Advances in Stem Cell ...
(Date:5/20/2013)... 2013  AbbVie (NYSE: ABBV ) ... clinical study called SONAR (Study Of Diabetic Nephropathy ... investigational compound atrasentan - when added to standard of ... with stage 2 to 4 chronic kidney disease ... large, multinational, double-blind, placebo-controlled clinical study that is ...
(Date:5/20/2013)... 20, 2013 With herbal medicines relied upon ... the U.S. Pharmacopeial Convention (USP) will provide freely available ... herbal ingredients used in these products. Today, USP proposes ... new Herbal Medicines Compendium ( HMC ) ... hmc.usp.org . HMC will provide ...
Breaking Medicine Technology:Neuralstem ALS Trial Principal Investigator, Dr. Eva Feldman, Presented Phase I Data At The Neuro Diabetes Medical Symposium In Romania 2Neuralstem ALS Trial Principal Investigator, Dr. Eva Feldman, Presented Phase I Data At The Neuro Diabetes Medical Symposium In Romania 3Neuralstem ALS Trial Principal Investigator, Dr. Eva Feldman, Presented Phase I Data At The Neuro Diabetes Medical Symposium In Romania 4AbbVie Initiates Phase 3 Study of Its Investigational Compound Atrasentan on Renal Outcomes in Patients with Diabetic Nephropathy 2AbbVie Initiates Phase 3 Study of Its Investigational Compound Atrasentan on Renal Outcomes in Patients with Diabetic Nephropathy 3AbbVie Initiates Phase 3 Study of Its Investigational Compound Atrasentan on Renal Outcomes in Patients with Diabetic Nephropathy 4AbbVie Initiates Phase 3 Study of Its Investigational Compound Atrasentan on Renal Outcomes in Patients with Diabetic Nephropathy 5AbbVie Initiates Phase 3 Study of Its Investigational Compound Atrasentan on Renal Outcomes in Patients with Diabetic Nephropathy 6New Compendium Offers Freely Available Testing Standards to Help Ensure the Quality of Herbal Ingredients Used in Traditional Medicines 2New Compendium Offers Freely Available Testing Standards to Help Ensure the Quality of Herbal Ingredients Used in Traditional Medicines 3
(Date:5/20/2013)... When people have lap ... become a celebrity. New Jersey governor Chris Christie, ... report (“Chris Christie Says Lap Band Surgery Is ... surgery was not done so that he could ... as a former lap band patient. Simply put, ...
(Date:5/20/2013)... Fountain Valley, CA (PRWEB) May 20, 2013 ... few dental professionals certified and trained to use the ... surgery designed to treat patients with gum disease. ... already lost teeth due to gum disease restore the ... disease begins with the buildup of plaque and tartar ...
(Date:5/20/2013)... 20, 2013 Mombo from Comfort ... conference of the US Lactation Consultant Association (USLCA) May ... nurses, doctors and other health professionals. , The ... helping lactation professionals discover and learn about the latest ... the most popular nursing pillows, which new mothers use ...
(Date:5/20/2013)... According to a May 6, 2013 CBS News article, ... tanning salons in the US may soon have to ... to see cancer warnings on indoor tanning beds ... for the use of indoor tanning and sun beds. The ... increasingly common over the last few decades (Go to goo.gl/TCT6m). ...
(Date:5/20/2013)... According to a June 2009 Bloomberg article, it ... to approximately $3.6 billion dollars per year (i). ... that there 15 million incidents of medical harm each ... who receives any form of medical treatment should be ... defines malpractice as “a dereliction of professional duty or ...
Breaking Medicine News(10 mins):Health News:The Lap Band Center: Dr. Atul Madan Applauds Chris Christie's Dedication to Family and Loss of 30 Pounds After Lap Band Surgery 2Health News:The Lap Band Center: Dr. Atul Madan Applauds Chris Christie's Dedication to Family and Loss of 30 Pounds After Lap Band Surgery 3Health News:Fountain Valley, Ca Gum Disease Patients with Missing Teeth Can Now Receive Laser Gum Surgery from Dr. Robert Mokbel for Success with Dental Implants 2Health News:Comfort & Harmony™ Exhibited mombo™ Nursing Pillow at USLCA’s First Inaugural Conference 2Health News:Tanning - FDA Wants Tanning Salons to Post Cancer Warning Signs 2Health News:Law Firm Releases New Informational Graphic on the Basics of Understanding Medical Malpractice Cases 2
... /PRNewswire-Asia/ -- China Medicine Corporation,(OTC Bulletin Board: ... developer,and leading distributor of prescription and over-the-counter ... devices, and medical formulations in the People,s ... its Annual Meeting of Shareholders (the,AMS,) on ...
... tastes, sexual stimuli may also key personality disorders , , ... brain that process pleasurable experiences such as sweet tastes ... whether an individual is a "people person," say European ... brains of 41 males who,d completed a questionnaire designed ...
... to do so, study finds , , WEDNESDAY, May 20 (HealthDay ... healthfully or boost physical activity can significantly improve health habits, ... e-mail program walked more, ate more fruits and vegetables and ... didn,t receive the e-mails, according to a report in the ...
... Distinction" to its Dispensing Safety CredentialsATLANTA, May ... today it has granted the first-ever GREENGUARD ... equipment to Parata(R) Systems. Parata RDS is ... to receive this important designation. (Logo: ...
... now has a relevant interest in more than 50 ... Inc. (Nasdaq: CEPH ) announced today that ... now has a relevant interest in 50.1 percent of ... Offer for the company free from all outstanding conditions. ...
... moderate COPD were randomized to receive "usual care" ... that offered an intensive lifestyle moderation phase of ... detail to perform two 15-minute intervals of pleasurable ... lifestyle changes such as nutrition and smoking cessation. ...
Cached Medicine News:Health News:China Medicine Corporation Holds Annual General Meeting of Shareholders 2Health News:Being a 'People Person' May Be All in Your Head 2Health News:E-Mailing Your Way to Healthier Habits 2Health News:E-Mailing Your Way to Healthier Habits 3Health News:Parata Earns Pharmacy Industry's First-Ever GREENGUARD Certification for Indoor Air Quality 2Health News:Parata Earns Pharmacy Industry's First-Ever GREENGUARD Certification for Indoor Air Quality 3Health News:Parata Earns Pharmacy Industry's First-Ever GREENGUARD Certification for Indoor Air Quality 4Health News:Cephalon Acquires Controlling Interest in Arana Therapeutics 2Health News:Cephalon Acquires Controlling Interest in Arana Therapeutics 3Health News:Cephalon Acquires Controlling Interest in Arana Therapeutics 4Health News:Lifestyle program for patients with COPD is health and cost effective 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: