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Effient® Added to Updated ACCF/AHA Clinical Guidelines for ACS-PCI Patients with Unstable Angina and Non-ST Segment Myocardial Infarction
Date:3/29/2011

co-developed Effient, an oral antiplatelet agent discovered by Daiichi Sankyo and its Japanese research partner, Ube Industries, Ltd. Effient helps keep blood platelets from clumping together and developing a blockage in an artery. Effient is approved by the U.S. Food and Drug Administration for the reduction of thrombotic cardiovascular events (including stent thrombosis) in patients with ACS who are managed with an artery-opening procedure known as PCI. PCI usually includes the placement of a stent to help keep the artery open.

About Acute Coronary Syndrome

ACS, which includes heart attack and a type of chest pain called unstable angina, affects more than one million people in the United States annually.(2) In 2010, an estimated 610,000 Americans had a new heart attack, and about 325,000 had a recurrent attack.(2) Each year, approximately 645,000 people with ACS are managed with PCI, which typically includes the implantation of a stent that restores blood flow to blocked arteries in the heart.(3) ACS results in significant illness and death, costing Americans more than $150 billion each year.(3) Nearly 60 percent of the U.S. healthcare costs of ACS are due to re-hospitalization.(3) Strategies to prevent recurrent heart attacks and re-hospitalization are important to improve patient outcomes and reduce the cost burden of ACS.(3)

Important Safety Information

What is the most important information patients should know about Effient?

Effient® (prasugrel) can cause bleeding. If patients have unexplained or excessive bleeding while on Effient, they should contact their doctor right away as some bleeding can be serious, and sometimes fatal. Patients should not take Effient if they currently have abnormal bleeding, such as stomach or intestinal bleeding, bleeding in their head, or have a history of stroke, or “mini-stroke” (transient ischemic attack or TIA). Patients should stop taking Effie
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SOURCE Daiichi Sankyo Company, Limited; Eli Lilly and Company
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