Navigation Links
deCODE Discovers Second Common Genetic Risk Factor for Atrial Fibrillation and Stroke
Date:7/13/2009

REYKJAVIK, Iceland, July 13 /PRNewswire-FirstCall/ -- Scientists at deCODE genetics (Nasdaq: DCGN) and colleagues from Europe and the United States today report the discovery of a common single-letter variant in the sequence of the human genome (SNP) conferring increased risk of atrial fibrillation (AF) and stroke. The findings will be integrated directly into the deCODE AF(TM) reference laboratory test for gauging individual risk of AF and stroke and helping to identify stroke patients who may benefit from enhanced monitoring for AF. The study is published online today in Nature Genetics at http://www.nature.com/ng.

The new SNP is in the ZFHX3 gene on chromosome 16q22, and the more than one third of people of European descent who carry one copy are at approximately 20% greater risk of AF and cardioembolic stroke than are individuals who carry none. AF is the most common type of cardiac arrhythmia, and is a major risk factor for stroke. Because AF is often intermittent and difficult to detect, gauging genetic susceptibility can help doctors to decide which of their stroke patients might benefit from longer-term monitoring for AF following a stroke. Those with stroke due to AF may be given different therapy than they would otherwise. This is the purpose of deCODE AF(TM), at the heart of which is the major AF and stroke variant discovered by deCODE on 4q25. Indeed today's findings are the result of deCODE's program to build on this work and to find new risk variants. After expanding their genome-wide association study in Iceland, the deCODE team took the top SNPs outside the 4q25 region and typed them in case-control cohorts from Iceland, Norway and the United States. This confirmed the ZFHX3 SNP as a risk variant for AF. Analysis in stroke cohorts from Iceland, Germany, Sw
'/>"/>

SOURCE DeCODE Genetics Inc
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. deCODE Launches Phase II Clinical Testing of DG051 for the Prevention of Heart Attack
2. deCODE Launches deCODE MI(TM) -- A Test for a Major Genetic Risk Factor for Early-onset Heart Attack
3. deCODE Launches a DNA-Based Test for Assessing Risk of Prostate Cancer on the Back of the Discovery of New Prostate Cancer Genes
4. deCODE Obesity Study Sheds Light on How Genetics Affects Risk and Onset of Common Diseases
5. deCODE Discovers Novel Genetic Links Between Pigmentation Traits and Risk of Skin Cancer
6. Marketing of Diagnostics and deCODEme(TM), Recent Progress in Drug Development to be Highlighted at deCODE R&D Event
7. deCODE and SGENE Consortium Discover Deletions in the Human Genome Linked to Risk of Schizophrenia
8. deCODE and Radboud University Discover Common Variants in the Human Genome Conferring Risk of Bladder Cancer
9. deCODE Files IND for DG071, a Novel PDE4 Modulator Being Developed for Alzheimers and Other Cognitive Disorders
10. Major deCODE-led Study Underscores Role of the Brain in Obesity
11. A Milestone in Cancer Genetics: deCODE Discovers First Common Genetic Variants Affecting the Risk of Many Types of Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... 19, 2014 The Parenteral Drug Association (PDA) ... post-approval changes protocols. The new initiative ... expressed by industry participants and regulatory authority representatives at ... in Washington, DC . Representatives of ... for the workshop. Attendees indicated openness to engaging regulators ...
(Date:9/19/2014)... , September 19, 2014 ... ) has announced the addition of the ... report to their offering.      ... have been broadly classified into wide categories ... used for the treatment of different gynecological ...
(Date:9/19/2014)... , Sept. 19, 2014  For Cloud Pharmaceuticals, ... design and development, partnering is an integral part ... to design new drugs and identify early stage, ... to further their development. The company also partners ... support this business model, Cloud Pharmaceuticals will be ...
Breaking Medicine Technology:PDA Launches Effort to Harmonize Global Post-Approval Changes Protocols 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 2Global Gynecological Devices Market 2014-2018: Key Vendors are Bayer, Boston Scientific, CooperSurgical, Ethicon, Hologic, Medtronic, Olympus and Stryker 3Cloud Pharmaceuticals Announces Partnering Sessions and Presentation Schedule 2
... 15, 2012  IntelligentMDx (IMDx) announced today that it has ... in vitro diagnostic test designed for the rapid ... use in screening pregnant women and those in labor ... responsible for life-threatening bacterial infections in newborns, including sepsis, ...
... YORK, May 15, 2012 ... market research report is available ...   ... Trends, Marketing Spend and Sales ...
Cached Medicine Technology:IntelligentMDx Announces CE-Marking of a new high-throughput test for Group B Streptococcus intended to improve women's health and prenatal care 2Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 2Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 3Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 4Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 5Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 6Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 7Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 8Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 9Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 10Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 11Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 12Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 13Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 14Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 15Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 16Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 17Global Pharmaceutical Survey 2012-2013: Market Trends, Marketing Spend and Sales Strategies in the Global Pharmaceutical Industry 18
(Date:9/19/2014)... AZ (PRWEB) September 19, 2014 Hastings and ... 30 years in the industry, announces a record number of ... handles a wide variety of serious injury cases as well ... along with dog bite related accident cases and others. Having ... and Hastings has stood the test of time when it ...
(Date:9/19/2014)... U.S. military troops deployed to sunny climates may have ... new study. Many returning troops reported getting ... military personnel developed blisters on their skin or noticed ... their moles since being deployed overseas. All of ... the study authors noted. "The past decade of ...
(Date:9/19/2014)... HealthDay Reporter THURSDAY, Sept. 18, ... and family conflicts before surgery may face a higher ... suggests. Investigators found that patients with a so-called ... greater risk for complications compared to those with a ... known that patient quality of life is a complex ...
(Date:9/19/2014)... (PRWEB) September 19, 2014 "I have ... getting wrinkles due to stretching the skin around my ... Ala. "This inspired me to design a more convenient ... CONTACT LENS SYSTEM provides a quicker, easier, more sanitary ... need to perform this task manually, saves time and ...
(Date:9/19/2014)... Jacksonville,s campus of Mayo Clinic have discovered a defect ... both overproduction of toxic protein in the brains of ... of communication between neurons both significant contributors to ... online issue of Neuron , offers ... "may rejuvenate or rescue this pathway," says the study,s ...
Breaking Medicine News(10 mins):Health News:Hastings And Hastings Announces a Record Number of Visitors to Its New Phoenix Personal Injury Website 2Health News:Some U.S. Troops May Face Greater Skin Cancer Risk 2Health News:Family Squabbles Can Derail Recovery From Cancer Surgery 2Health News:Family Squabbles Can Derail Recovery From Cancer Surgery 3Health News:Mayo researchers reveal pathway that contributes to Alzheimer's disease 2
... Swven staff at RMIT University in Melbourne, working just meters below ... with brain tumors. // ,Following the report of these ... building and plans to begin immediate health and safety testing. ... top two floors of the Bourke St building and have developed ...
... Parliament says that almost a thousand people end up in ... report, which was available in the parliament yesterday, showed that ... year." This was indeed a massive jump when compared with ... is growing at an alarming rate, so we need action ...
... According to a recent study conducted by the researchers at ... one in seven East Asian immigrants are carriers// of the ... liver cancer and cirrhosis. But it is surprising to know ... infected. Three-quarters of these people who are infected had no ...
... Health workers by the Ontario government, to beat a possible ... from critics // , who see this is politically motivated ... The opinion doing the rounds is that the kits ... ,According to health minister George Smitherman, 15,000 emergency kits will ...
... have developed ,the first knee replacement shaped to fit ... U.S. Food and Drug Administration, and will be distributed ... Aaron G. Rosenberg and Dr. Richard A. Berger, orthopedic ... sought to address shape-related differences of a woman’s knee. ...
... has lost a third of their value on Wednesday after ... treatment against the hepatitis C virus. // ... percent, to $4.83, in the heavy morning trade on the ... that the results came from the second stage of a ...
Cached Medicine News:Health News:RMIT Staff Diagnosed with Brain Tumors 2Health News:East Asian Immigrants Bring Hepatitis to New York 2Health News:Shapelier Knee Replacements for Women 2Health News:Shapelier Knee Replacements for Women 3Health News:Shapelier Knee Replacements for Women 4
... features including aspiration holes and additional ... procedures requiring precise dissection with decreased ... suction demands. ,Flexible design options ... nonretractable electrodes and multiple tip designs. ...
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
... Instruments incorporate a layered design unique in ... monitored to prevent stray electrosurgical burns along ... insulation failure or capacitive coupling; a well-documented ... into all AEM Instruments provides a neutral ...
Medicine Products: