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deCODE Discovers Four New Risk Factors for Prostate Cancer
Date:9/20/2009

it most from intensive screening. We are pleased to be incorporating these latest markers into our deCODE ProstateCancer(TM) test," said Kari Stefansson, CEO of deCODE.

Today's findings result from the analysis of several large datasets: deCODE's genome-wide SNP data from tens of thousands of patients and healthy controls from Iceland; sequencing data from regions in the genome where deCODE and others have already discovered prostate cancer risk factors; and publicly available data from other case-control cohorts from the US, France and Finland. Data from a combined total of more than 60,000 patients and healthy control subjects were included in the study.

The paper, 'Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility,' is published today in the online edition of Nature Genetics, at http://www.nature.com/ng.

Acknowledgements

deCODE wishes to thank the patients and control subjects from many countries whose participation made this work possible. This study was funded in part by the European Union's PROMARK and CancerGene grants to deCODE; by the US Department of Veterans Affairs, and by the Academy of Finland, Sigrid Juselius Foundation, Finnish Cancer Organizations, and Pirkanmaa Hospital.

About deCODE

deCODE is a global leader in analysing and understanding the human genome. The company has identified key variations in the sequence of the genome conferring increased risk of major public health challenges from cardiovascular disease to cancer, and employs its gene discovery engine to develop DNA-based tests to assess individual risk of common diseases; to license its tests and intellectual property to partners; and to provide comprehensive, leading- edge contract services to companies and research institutions around
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