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bioTheranostics' CancerTYPE ID® Linked With Improved Clinical Outcome and Longer Survival
Date:11/2/2011

SAN DIEGO, Nov. 2, 2011 /PRNewswire/ -- bioTheranostics, Inc., a bioMerieux company that develops innovative oncology diagnostic tests to drive personalized treatment, today announced clinical study findings that link CancerTYPE ID® molecular testing with improved patient outcome.  Patients in which CancerTYPE ID predicted a colorectal site of origin that subsequently received site-specific therapy had a median survival three times that of what has been reported in patients treated empirically for cancer of unknown primary (CUP). These results make CancerTYPE ID the only marketed molecular cancer classifier to demonstrate therapeutic response and patient benefit based on molecular tumor profiling.

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The study, led by John Hainsworth, MD, of the Sarah Canon Research Institute,  A Retrospective Study of Treatment Outcomes in Patients with Carcinoma of Unknown Primary Site and a Colorectal Cancer Molecular Profile, focused on the improved treatment response and survival in a group of patients in which CancerTYPE ID results were utilized in the selection of site-specific therapy.  According to the study findings, which will be published in the December issue of Clinical Colorectal Cancer and currently are available online, 75 percent of the patients showed negative colonoscopy results, and approximately half the patients had atypical immunohistochemistry for colorectal cancer. Significantly, CancerTYPE ID was used as part of the routine work-up and site-specific treatment was selected based on the molecular assay prediction.  

The study results demonstrated a 50 percent response rate in patients treated with first-line regimens for colorectal cancer versus only 17 percent in patients treated with current empiric therapies for CUP (P value = 0.0257).  Patients predicted
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SOURCE bioTheranostics, Inc.
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